NCNA (NuCana) E10: $0.00 (As of Mar. 2026)


NCNA NuCana PLC NCNA
25 GF Score
Price $1.51
! 2 Warning Signs
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What is NuCana E10?

NuCana NCNA -4.91% 25 E10 is $0.00 as of Mar. 2026. GuruFocus rates NCNA with a GF Score™ of 25/100. The stock has 2 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

NuCana's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was $0.000. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $0.00 for the trailing ten years ended in Dec. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-06-28), NuCana's current stock price is $ 1.5114. NuCana's E10 for the fiscal year that ended in Dec. 2025 was $0.00. NuCana's Shiller PE Ratio of today is .


NuCana  (NAS:NCNA) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


NuCana E10 Related Terms


NuCana E10 Historical Data

* Premium members only.

The historical data trend for NuCana's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

NuCana E10 Chart

NuCana Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -4,180.15 0.00

NuCana Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

NCNA vs PBM, LABT, CURX: E10 Comparison

For the Biotechnology subindustry, NuCana's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


NuCana Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, NuCana's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where NuCana's Shiller PE Ratio falls into.


NCNA
25GF Score
NuCana PLC NCNA
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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NuCana E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, NuCana's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was:

Adj_EPS=Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=0/139.9000*139.9000
=0.000

Current CPI (Dec. 2025) = 139.9000.

NuCana Annual Data

per_share_eps CPI Adj_EPS
201612 -1,222.702 102.200 -1,673.738
201712 -5,965.147 105.000 -7,947.848
201812 -2,721.519 107.100 -3,555.000
201912 -4,325.033 108.500 -5,576.702
202012 -5,443.548 109.400 -6,961.173
202112 -5,186.170 114.700 -6,325.590
202212 -3,714.982 125.300 -4,147.853
202312 -3,354.430 130.500 -3,596.052
202412 -1,643.489 135.100 -1,701.881
202512 0.000 139.900 0.000

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $0.00 mean?
NuCana (NCNA) has a E10 of $0.00 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on NuCana and its competitors.
Is NuCana's E10 too high?
NuCana's current E10 is $0.00. Overall, NuCana has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does NuCana's E10 compare to PBM and LABT?
NuCana's E10 of $0.00 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on NuCana and its competitors. NuCana's current E10 is $0.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is NuCana stock overvalued right now?
NuCana (NCNA) has a current E10 of $0.00. The current E10 is $0.00. NuCana's overall GF Score™ is 25/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For NuCana (NCNA), the current E10 is $0.00 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

NuCana Business Description

Address 3 Lochside Way, Edinburgh, GBR, EH12 9DT
NuCana PLC is a biopharmaceutical company focused on improving treatment outcomes for cancer patients by ProTide technology. Utilizing proprietary ProTide technology, the firm is developing new medicines designed to overcome key cancer resistance mechanisms and generate much higher concentrations of anti-cancer metabolites in cancer cells. The company's ProTide pipeline products are NUC-3373, NUC-7738, Acelarin. Geographically operates through the region of the United States and the United Kingdom.
25GF Score

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