SKYE (Skye Bioscience) E10: $-20.57 (As of Mar. 2026)


SKYE Skye Bioscience Inc SKYE
30 GF Score
Price $0.71
! 1 Warning Sign
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What is Skye Bioscience E10?

Skye Bioscience SKYE -0.28% 30 E10 is $-20.57 as of Mar. 2026. GuruFocus rates SKYE with a GF Score™ of 30/100. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Skye Bioscience's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.320. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-20.57 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average E10 Growth Rate was 12.90% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Skye Bioscience was 12.90% per year. The lowest was 12.90% per year. And the median was 12.90% per year.

As of today (2026-07-08), Skye Bioscience's current stock price is $0.706. Skye Bioscience's E10 for the quarter that ended in Mar. 2026 was $-20.57. Skye Bioscience's Shiller PE Ratio of today is .


Skye Bioscience  (NAS:SKYE) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Skye Bioscience E10 Related Terms


Skye Bioscience E10 Historical Data

* Premium members only.

The historical data trend for Skye Bioscience's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Skye Bioscience E10 Chart

Skye Bioscience Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -34.73 -36.47 -32.42 -22.94

Skye Bioscience Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -30.79 -26.60 -24.37 -22.94 -20.57

SKYE vs PLRZ, NEUP, LGVN: E10 Comparison

For the Biotechnology subindustry, Skye Bioscience's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Skye Bioscience Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Skye Bioscience's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Skye Bioscience's Shiller PE Ratio falls into.


SKYE
30GF Score
Skye Bioscience Inc SKYE
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Skye Bioscience E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Skye Bioscience's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.32/330.2130*330.2130
=-0.320

Current CPI (Mar. 2026) = 330.2130.

Skye Bioscience Quarterly Data

per share eps CPI Adj_EPS
201606 7.500 241.018 10.276
201609 -12.500 241.428 -17.097
201612 -17.500 241.432 -23.935
201703 -22.500 243.801 -30.475
201706 -5.000 244.955 -6.740
201709 -5.000 246.819 -6.689
201712 2.500 246.524 3.349
201803 -22.500 249.554 -29.772
201806 -5.000 251.989 -6.552
201809 -5.000 252.439 -6.540
201812 -12.500 251.233 -16.430
201903 -27.500 254.202 -35.723
201906 20.000 256.143 25.783
201909 -10.000 256.759 -12.861
201912 -5.000 256.974 -6.425
202003 -2.500 258.115 -3.198
202006 -2.500 257.797 -3.202
202009 -2.500 260.280 -3.172
202012 -2.500 260.474 -3.169
202103 -2.500 264.877 -3.117
202106 -2.500 271.696 -3.038
202109 -1.103 274.310 -1.328
202112 0.000 278.802 0.000
202203 -2.500 287.504 -2.871
202206 -2.500 296.311 -2.786
202209 -1.580 296.808 -1.758
202212 -3.940 296.797 -4.384
202303 -1.370 301.836 -1.499
202306 -0.800 305.109 -0.866
202309 -3.170 307.789 -3.401
202312 -0.358 306.746 -0.385
202403 -0.180 312.332 -0.190
202406 -0.200 314.175 -0.210
202409 -0.100 315.301 -0.105
202412 -0.240 315.605 -0.251
202503 -0.280 319.799 -0.289
202506 -0.440 322.561 -0.450
202509 -0.320 324.800 -0.325
202512 -0.360 324.054 -0.367
202603 -0.320 330.213 -0.320

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-20.57 mean?
Skye Bioscience (SKYE) has a E10 of $-20.57 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Skye Bioscience and its competitors.
Is Skye Bioscience's E10 too high?
Skye Bioscience's current E10 is $-20.57. Overall, Skye Bioscience has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Skye Bioscience's E10 compare to PLRZ and NEUP?
Skye Bioscience's E10 of $-20.57 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Skye Bioscience and its competitors. Skye Bioscience's current E10 is $-20.57. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Skye Bioscience stock overvalued right now?
Skye Bioscience (SKYE) has a current E10 of $-20.57. The current E10 is $-20.57. Skye Bioscience's overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Skye Bioscience (SKYE), the current E10 is $-20.57 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Skye Bioscience Business Description

Other Exchanges 09R:Germany
Address 11250 El Camino Real, Suite 100, San Diego, CA, USA, 92130
Skye Bioscience Inc is a pre-clinical pharmaceutical company located in San Diego, California. The company's clinical assets focus on the modulation of cannabinoid receptor 1 ("CB1") to provide novel treatments and alternatives for diseases caused by metabolic disorders, inflammation, fibrosis, and neurodegeneration, such as obesity and glaucoma. The company's Phase 2 clinical candidates include nimacimab, a negative allosteric modulating antibody that inhibits peripheral CB1 receptors, currently being developed for the treatment of obesity and SBI-100 Ophthalmic Emulsion ("SBI-100 OE"), a CB1 agonist (activator), currently being developed for the treatment of glaucoma and ocular hypertension.
30GF Score

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