Shionogi (TSE:4507) E10: 円180.15 (As of Jun. 2026)

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Vera Yuan
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Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
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Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TSE:4507 Shionogi & Co Ltd TSE:4507
83 GF Score
Price 円2,909.00
GF Value 円3,298.38
Valuation Modestly Undervalued
! 3 Warning Signs
View Full Analysis

What is Shionogi E10?

Shionogi TSE:4507 -2.77% 83 E10 is 円180.15 as of Jun. 2026. GuruFocus rates TSE:4507 with a GF Score™ of 83/100 and a GF Value™ of 円3,298.38 (Modestly Undervalued). The stock has 3 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Shionogi's adjusted earnings per share data for the three months ended in Jun. 2026 was 円114.780. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円180.15 for the trailing ten years ended in Jun. 2026.

During the past 12 months, Shionogi's average E10 Growth Rate was 16.60% per year. During the past 3 years, the average E10 Growth Rate was 14.30% per year. During the past 5 years, the average E10 Growth Rate was 15.00% per year. During the past 10 years, the average E10 Growth Rate was 15.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Shionogi was 17.60% per year. The lowest was 13.30% per year. And the median was 15.55% per year.

As of today (2026-09-06), Shionogi's current stock price is 円2909.00. Shionogi's E10 for the quarter that ended in Jun. 2026 was 円180.15. Shionogi's Shiller PE Ratio of today is 16.15.

During the past 13 years, the highest Shiller PE Ratio of Shionogi was 45.41. The lowest was 14.37. And the median was 23.44.


Shionogi  (TSE:4507) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Shionogi's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=2909.00/180.15
=16.15

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Shionogi was 45.41. The lowest was 14.37. And the median was 23.44.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Shionogi E10 Related Terms


Shionogi E10 Historical Data

* Premium members only.

The historical data trend for Shionogi's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Shionogi E10 Chart

Shionogi Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 96.32 113.06 130.18 150.19 168.79

Shionogi Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 154.52 158.78 166.62 168.79 180.15

TSE:4507 vs ZTS: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Shionogi's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Shionogi Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Shionogi's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Shionogi's Shiller PE Ratio falls into.


TSE:4507
83GF Score
Shionogi & Co Ltd TSE:4507
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Shionogi E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Shionogi's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=114.78/113.6000*113.6000
=114.780

Current CPI (Jun. 2026) = 113.6000.

Shionogi Quarterly Data

per share eps CPI Adj_EPS
201609 18.813 98.000 21.808
201612 36.950 98.400 42.658
201703 16.890 98.100 19.559
201706 16.477 98.500 19.003
201709 35.330 98.800 40.622
201712 30.293 99.400 34.621
201803 30.377 99.200 34.787
201806 33.317 99.200 38.153
201809 27.230 99.900 30.964
201812 38.713 99.700 44.110
201903 45.643 99.700 52.006
201906 29.007 99.800 33.018
201909 29.137 100.100 33.067
201912 43.093 100.500 48.710
202003 30.623 100.300 34.684
202006 26.860 99.900 30.544
202009 29.907 99.900 34.008
202012 39.637 99.300 45.345
202103 25.160 99.900 28.610
202106 35.637 99.500 40.687
202109 23.090 100.100 26.204
202112 19.750 100.100 22.414
202203 47.733 101.100 53.635
202206 38.377 101.800 42.825
202209 24.987 103.100 27.532
202212 113.327 104.100 123.669
202303 31.157 104.400 33.903
202306 48.190 105.200 52.038
202309 54.673 106.200 58.483
202312 42.297 106.800 44.990
202403 40.863 107.200 43.303
202406 36.010 108.200 37.807
202409 61.690 108.900 64.352
202412 59.550 110.700 61.110
202503 43.040 111.100 44.008
202506 46.250 111.700 47.037
202509 51.910 112.000 52.652
202512 87.750 113.000 88.216
202603 55.130 112.700 55.570
202606 114.780 113.600 114.780

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円180.15 mean?
Shionogi (TSE:4507) has a E10 of 円180.15 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Shionogi and its competitors.
Is Shionogi's E10 too high?
Shionogi's current E10 is 円180.15. Overall, Shionogi has a GF Score™ of 83/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Shionogi's E10 compare to ZTS?
Shionogi's E10 of 円180.15 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Shionogi and its competitors. Shionogi's current E10 is 円180.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shionogi stock overvalued right now?
Based on GuruFocus' analysis, Shionogi (TSE:4507) is currently considered Modestly Undervalued. The stock's GF Value™ is 円3,298.38, compared to a current price of 円2,909.00 — trading 11.8% below its estimated fair value. The current E10 is 円180.15. Shionogi's overall GF Score™ is 83/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Shionogi (TSE:4507), the current E10 is 円180.15 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Shionogi (TSE:4507) Overvalued in 2026?

Based on GuruFocus' analysis, Shionogi stock appears to be undervalued. The current stock price of 円2,909.00 is trading 11.8% below its estimated GF Value™ of 円3,298.38. GuruFocus considers Shionogi to be Modestly Undervalued.

Key valuation signals for TSE:4507:

  • E10: 円180.15
  • GF Value™: 円3,298.38 vs. price of 円2,909.00 (11.8% below fair value)
  • GF Score™: 83/100 with 3 warning signs

No single metric tells the full story. See the TSE:4507 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Shionogi Business Description

Address 3-1-8 Doshomachi, Chuo-ku, Osaka, JPN, 541-0045
Shionogi & Co Ltd is a specialty and generic drug manufacturing company. The company focuses on the manufacturing and distribution of pharmaceuticals, diagnostic reagents, and medical devices. The company engages in manufacturing, formulation, packaging, and analysis as part of its commercialization research that spans late-stage drug discovery through commercial production. It provides products and services in Japan, Europe, North America, and other regions.
83GF Score

Get the complete analysis for TSE:4507

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,909.00
Price
円3,298.38
GF Value