Roche Holding AG (XSWX:ROP) E10: CHF14.35 (As of Dec. 2025)


XSWX:ROP Roche Holding AG XSWX:ROP
79 GF Score
Price CHF332.00
GF Value CHF264.69
Valuation Modestly Overvalued
! 3 Warning Signs
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What is Roche Holding AG E10?

Roche Holding AG XSWX:ROP +2.09% 79 E10 is CHF14.35 as of Dec. 2025. GuruFocus rates XSWX:ROP with a GF Score™ of 79/100 and a GF Value™ of CHF264.69 (Modestly Overvalued). The stock has 3 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Roche Holding AG's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was CHF16.040. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is CHF14.35 for the trailing ten years ended in Dec. 2025.

During the past 12 months, Roche Holding AG's average E10 Growth Rate was 3.60% per year. During the past 3 years, the average E10 Growth Rate was 1.90% per year. During the past 5 years, the average E10 Growth Rate was 3.20% per year. During the past 10 years, the average E10 Growth Rate was 3.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Roche Holding AG was 13.10% per year. The lowest was 1.20% per year. And the median was 3.95% per year.

As of today (2026-06-25), Roche Holding AG's current stock price is CHF 332.00. Roche Holding AG's E10 for the fiscal year that ended in Dec. 2025 was CHF14.35. Roche Holding AG's Shiller PE Ratio of today is 23.14.

During the past 13 years, the highest Shiller PE Ratio of Roche Holding AG was 31.26. The lowest was 15.66. And the median was 23.20.


Roche Holding AG  (XSWX:ROP) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Roche Holding AG's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=332.00/14.35
=23.14

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Roche Holding AG was 31.26. The lowest was 15.66. And the median was 23.20.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Roche Holding AG E10 Related Terms


Roche Holding AG E10 Historical Data

* Premium members only.

The historical data trend for Roche Holding AG's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Roche Holding AG E10 Chart

Roche Holding AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 12.82 13.58 13.88 13.85 14.35

Roche Holding AG Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 13.88 0.00 13.85 0.00 14.35

XSWX:ROP vs LLY, JNJ, ABBV: E10 Comparison

For the Drug Manufacturers - General subindustry, Roche Holding AG's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Roche Holding AG Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Roche Holding AG's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Roche Holding AG's Shiller PE Ratio falls into.


XSWX:ROP
79GF Score
Roche Holding AG XSWX:ROP
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Roche Holding AG E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Roche Holding AG's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was:

Adj_EPS=Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=16.04/107.1957*107.1957
=16.040

Current CPI (Dec. 2025) = 107.1957.

Roche Holding AG Annual Data

per_share_eps CPI Adj_EPS
201612 11.130 99.380 12.005
201712 10.040 100.213 10.740
201812 12.210 100.906 12.971
201912 15.620 101.063 16.568
202012 16.520 100.241 17.666
202112 16.200 101.776 17.063
202212 15.370 104.666 15.741
202312 14.310 106.461 14.409
202412 10.310 107.128 10.317
202512 16.040 107.196 16.040

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of CHF14.35 mean?
Roche Holding AG (XSWX:ROP) has a E10 of CHF14.35 as of Dec. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Roche Holding AG and its competitors.
Is Roche Holding AG's E10 too high?
Roche Holding AG's current E10 is CHF14.35. Overall, Roche Holding AG has a GF Score™ of 79/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Roche Holding AG's E10 compare to LLY and JNJ?
Roche Holding AG's E10 of CHF14.35 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Roche Holding AG and its competitors. Roche Holding AG's current E10 is CHF14.35. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Roche Holding AG stock overvalued right now?
Based on GuruFocus' analysis, Roche Holding AG (XSWX:ROP) is currently considered Modestly Overvalued. The stock's GF Value™ is CHF264.69, compared to a current price of CHF332.00 — trading 25.4% above its estimated fair value. The current E10 is CHF14.35. Roche Holding AG's overall GF Score™ is 79/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Roche Holding AG (XSWX:ROP), the current E10 is CHF14.35 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Roche Holding AG (XSWX:ROP) Overvalued in 2026?

Based on GuruFocus' analysis, Roche Holding AG stock appears to be overvalued. The current stock price of CHF332.00 is trading 25.4% above its estimated GF Value™ of CHF264.69. GuruFocus considers Roche Holding AG to be Modestly Overvalued.

Key valuation signals for XSWX:ROP:

  • E10: CHF14.35
  • GF Value™: CHF264.69 vs. price of CHF332.00 (25.4% above fair value)
  • GF Score™: 79/100 with 3 warning signs

No single metric tells the full story. See the XSWX:ROP stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Roche Holding AG Business Description

Address Grenzacherstrasse 124, Basel, CHE, 4070
Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 40% of pharmaceutical sales, and centralized and point-of-care diagnostics for two-thirds of diagnostic-related sales.
79GF Score

Get the complete analysis for XSWX:ROP

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

CHF332.00
Price
CHF264.69
GF Value