Roche Holding AG (XSWX:ROP) ROE % Adjusted to Book Value: 4.53% (As of Dec. 2025)


XSWX:ROP Roche Holding AG XSWX:ROP
77 GF Score
Price CHF336.00
GF Value CHF264.69
Valuation Modestly Overvalued
! 7 Warning Signs
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What is Roche Holding AG ROE % Adjusted to Book Value?

Roche Holding AG XSWX:ROP +0.21% 77 ROE % Adjusted to Book Value is 4.53% as of Dec. 2025. GuruFocus rates XSWX:ROP with a GF Score™ of 77/100 and a GF Value™ of CHF264.69 (Modestly Overvalued). The stock has 7 warning signs investors should review.

Roche Holding AG's ROE % for the quarter that ended in Dec. 2025 was 35.02%. Roche Holding AG's PB Ratio for the quarter that ended in Dec. 2025 was 7.73. Roche Holding AG's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was 4.53%.

Roche Holding AG ROE % Adjusted to Book Value Related Terms

Roche Holding AG ROE % Adjusted to Book Value Historical Data

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The historical data trend for Roche Holding AG's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Roche Holding AG ROE % Adjusted to Book Value Chart

Roche Holding AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.70 5.71 6.03 4.23 5.08

Roche Holding AG Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 4.70 6.25 2.08 6.83 4.53

XSWX:ROP vs LLY, JNJ, ABBV: ROE % Adjusted to Book Value Comparison

For the Drug Manufacturers - General subindustry, Roche Holding AG's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Roche Holding AG ROE % Adjusted to Book Value vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Roche Holding AG's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Roche Holding AG's ROE % Adjusted to Book Value falls into.


XSWX:ROP
77GF Score
Roche Holding AG XSWX:ROP
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Roche Holding AG ROE % Adjusted to Book Value Calculation

Roche Holding AG's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=39.29% / 7.73
=5.08%

Roche Holding AG's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=35.02% / 7.73
=4.53%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 4.53% mean?
Roche Holding AG (XSWX:ROP) has a ROE % Adjusted to Book Value of 4.53% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Roche Holding AG and its competitors.
Is Roche Holding AG's ROE % Adjusted to Book Value too high?
Roche Holding AG's current ROE % Adjusted to Book Value is 4.53%. Overall, Roche Holding AG has a GF Score™ of 77/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Roche Holding AG's ROE % Adjusted to Book Value compare to LLY and JNJ?
Roche Holding AG's ROE % Adjusted to Book Value of 4.53% can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Drug Manufacturers company?
A good ROE % Adjusted to Book Value depends on the Drug Manufacturers industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Roche Holding AG and its competitors. Roche Holding AG's current ROE % Adjusted to Book Value is 4.53%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Roche Holding AG stock overvalued right now?
Based on GuruFocus' analysis, Roche Holding AG (XSWX:ROP) is currently considered Modestly Overvalued. The stock's GF Value™ is CHF264.69, compared to a current price of CHF336.00 — trading 26.9% above its estimated fair value. The current ROE % Adjusted to Book Value is 4.53%. Roche Holding AG's overall GF Score™ is 77/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Roche Holding AG (XSWX:ROP), the current ROE % Adjusted to Book Value is 4.53% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Roche Holding AG (XSWX:ROP) Overvalued in 2026?

Based on GuruFocus' analysis, Roche Holding AG stock appears to be overvalued. The current stock price of CHF336.00 is trading 26.9% above its estimated GF Value™ of CHF264.69. GuruFocus considers Roche Holding AG to be Modestly Overvalued.

Key valuation signals for XSWX:ROP:

  • ROE % Adjusted to Book Value: 4.53%
  • GF Value™: CHF264.69 vs. price of CHF336.00 (26.9% above fair value)
  • GF Score™: 77/100 with 7 warning signs

No single metric tells the full story. See the XSWX:ROP stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Roche Holding AG Business Description

Address Grenzacherstrasse 124, Basel, CHE, 4070
Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 40% of pharmaceutical sales, and centralized and point-of-care diagnostics for two-thirds of diagnostic-related sales.
77GF Score

Get the complete analysis for XSWX:ROP

ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

CHF336.00
Price
CHF264.69
GF Value