ATXI (Avenue Therapeutics) Earnings Yield (Joel Greenblatt) %: 303.03% (As of Jun. 2026) — 94% Above Median

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ATXI Avenue Therapeutics Inc ATXI
32 GF Score
Price $0.26
! 1 Warning Sign
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What is Avenue Therapeutics Earnings Yield (Joel Greenblatt) %?

Avenue Therapeutics ATXI -8.21% 32 Earnings Yield (Joel Greenblatt) % is 303.03% as of Jun. 2026, which is 94% above its 10-year median of 156.05. GuruFocus rates ATXI with a GF Score™ of 32/100. The stock has 1 warning sign investors should review. Among 1,343 Biotechnology companies, Avenue Therapeutics ranks worse than 74460.09% on this metric.

Avenue Therapeutics's Enterprise Value for the quarter that ended in Jun. 2026 was $-1.02 Mil. Avenue Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was $-3.10 Mil. Avenue Therapeutics's Earnings Yield (Joel Greenblatt) for the quarter that ended in Jun. 2026 was 303.03%.

The historical rank and industry rank for Avenue Therapeutics's Earnings Yield (Joel Greenblatt) % or its related term are showing as below:

ATXI' s Earnings Yield (Joel Greenblatt) % Range Over the Past 10 Years
Min: 129.1   Med: 156.05   Max: 862.69
Current: 285.71

During the past 11 years, the highest Earnings Yield (Joel Greenblatt) of Avenue Therapeutics was 862.69%. The lowest was 129.10%. And the median was 156.05%.

ATXI's Earnings Yield (Joel Greenblatt) % is not ranked
in the Biotechnology industry.
Industry Median: -9.92 vs ATXI: 285.71

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

A better indicator of the attractiveness of an investment which takes growth into account is the Forward Rate of Return (Yacktman) %. Avenue Therapeutics's Forward Rate of Return (Yacktman) % for the quarter that ended in Jun. 2026 was 0.00%. The Forward Rate of Return uses the normalized Free Cash Flow of the past five years, and considers growth. The forward rate of return can be thought of as the return that investors buying the stock today can expect from it in the future.


Avenue Therapeutics  (OTCPK:ATXI) Earnings Yield (Joel Greenblatt) % Explanation

Joel Greenblatt defines the earnings yield using the above equation because it more accurately reflects the company's profitability relative to its stock price. Items like interest payment and tax etc. are not directly related to the company's operational profitability.

Enterprise Value instead of market cap (share price) is used in the calculation because it is the real price stock and bond investors together pay for the company.


Be Aware

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

Forward Rate of Return (Yacktman) % based on Don Yacktman's definition is a better measure of the expected rate of return for a stock.


Avenue Therapeutics Earnings Yield (Joel Greenblatt) % Related Terms


Avenue Therapeutics Earnings Yield (Joel Greenblatt) % Historical Data

* Premium members only.

The historical data trend for Avenue Therapeutics's Earnings Yield (Joel Greenblatt) % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Avenue Therapeutics Earnings Yield (Joel Greenblatt) % Chart

Avenue Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Earnings Yield (Joel Greenblatt) %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -23.87 136.99 -714.29 -1,666.67 476.19

Avenue Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Earnings Yield (Joel Greenblatt) % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 161.29 158.73 476.19 142.86 303.03

ATXI vs LYRA, ZVSA, VBIO: Earnings Yield (Joel Greenblatt) % Comparison

For the Biotechnology subindustry, Avenue Therapeutics's Earnings Yield (Joel Greenblatt) %, along with its competitors' market caps and Earnings Yield (Joel Greenblatt) % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Avenue Therapeutics Earnings Yield (Joel Greenblatt) % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Avenue Therapeutics's Earnings Yield (Joel Greenblatt) % distribution charts can be found below:

* The bar in red indicates where Avenue Therapeutics's Earnings Yield (Joel Greenblatt) % falls into.


ATXI
32GF Score
Avenue Therapeutics Inc ATXI
Earnings Yield (Joel Greenblatt) % is just one metric. See GF Score™, valuation, warning signs, and more.
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Avenue Therapeutics Earnings Yield (Joel Greenblatt) % Calculation

In his book, The Little That Beat the Market, hedge fund manager Joel Greenblatt defines Earnings Yield as operating income divided by enterprise value.

Avenue Therapeuticss Earnings Yield (Joel Greenblatt) for the fiscal year that ended in Dec. 2025 is calculated as

Earnings Yield (Joel Greenblatt)=EBIT/Enterprise Value
=-3.286/-0.6892432
=476.75 %

Avenue Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-3.10 Mil.


What does a Earnings Yield (Joel Greenblatt) % of 303.03% mean?
Avenue Therapeutics (ATXI) has a Earnings Yield (Joel Greenblatt) % of 303.03% as of Jun. 2026. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Avenue Therapeutics and its competitors. This is 94% above median its historical median of 156.05. Over the past decade, Avenue Therapeutics' Earnings Yield (Joel Greenblatt) % has ranged from 129.10 to 862.69. According to the industry distribution chart, Avenue Therapeutics ranks #999999 out of 1343 companies in the Biotechnology industry.
Is Avenue Therapeutics' Earnings Yield (Joel Greenblatt) % too high?
Avenue Therapeutics' current Earnings Yield (Joel Greenblatt) % of 303.03% is 94% above median its 10-year median of 156.05. Over the past 10 years, this metric has ranged from a low of 129.10 to a high of 862.69. Based on the distribution chart, Avenue Therapeutics ranks #999999 out of 1343 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Avenue Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Avenue Therapeutics' Earnings Yield (Joel Greenblatt) % compare to LYRA and ZVSA?
According to the Biotechnology industry distribution chart, Avenue Therapeutics ranks #999999 out of 1343 companies for Earnings Yield (Joel Greenblatt) %. This places Avenue Therapeutics in the lower half of its industry. Historically, Avenue Therapeutics' own Earnings Yield (Joel Greenblatt) % has ranged from 129.10 to 862.69 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings Yield (Joel Greenblatt) % for a Biotechnology company?
A good Earnings Yield (Joel Greenblatt) % depends on the Biotechnology industry context. However, Earnings Yield (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings Yield (Joel Greenblatt) % mean?
A high Earnings Yield (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Avenue Therapeutics and its competitors. Avenue Therapeutics's current Earnings Yield (Joel Greenblatt) % is 303.03%, which is 94% above median its own 10-year median of 156.05. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Avenue Therapeutics stock overvalued right now?
Avenue Therapeutics (ATXI) has a current Earnings Yield (Joel Greenblatt) % of 303.03%. The current Earnings Yield (Joel Greenblatt) % is 303.03%, which is 94% above median its 10-year median of 156.05. Avenue Therapeutics' overall GF Score™ is 32/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings Yield (Joel Greenblatt) % calculated?
Earnings Yield (Joel Greenblatt) % is calculated from a company's financial statements. For Avenue Therapeutics (ATXI), the current Earnings Yield (Joel Greenblatt) % is 303.03% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Avenue Therapeutics Business Description

Address 1111 Kane Concourse, Suite 301, Bay Harbor Islands, FL, USA, 33154
Avenue Therapeutics Inc is a specialty pharmaceutical company focused on the development and commercialization of therapies for the treatment of rare and neurologic diseases. It is focused on advancing impactful therapies with the potential to overcome limitations of existing treatment options and ultimately transform patient outcomes. Current product candidates include ATX-04, a selective beta adrenergic agonist for Pompe disease, intravenous tramadol (IV tramadol), a Schedule IV opioid for the treatment of post-operative acute pain, and BAER-101 for the treatment of epilepsy and panic disorders. The company operates in one reportable segment, the development and commercialization of therapies for the treatment of neurologic diseases.
32GF Score

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