ALNY (Alnylam Pharmaceuticals) EBIT: $870 Mil (TTM As of Mar. 2026)


ALNY Alnylam Pharmaceuticals Inc ALNY
74 GF Score
Price $291.76
GF Value $513.74
Valuation Significantly Undervalued
! 3 Warning Signs
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What is Alnylam Pharmaceuticals EBIT?

Alnylam Pharmaceuticals ALNY -0.78% 74 EBIT is $870 Mil as of Mar. 2026. GuruFocus rates ALNY with a GF Score™ of 74/100 and a GF Value™ of $513.74 (Significantly Undervalued). The stock has 3 warning signs investors should review.

Alnylam Pharmaceuticals's earnings before interest and taxes (EBIT) for the three months ended in Mar. 2026 was $291 Mil. Its earnings before interest and taxes (EBIT) for the trailing twelve months (TTM) ended in Mar. 2026 was $870 Mil.

EBIT or Operating Income is linked to Return on Capital for both regular definition and Joel Greenblatt's definition. Alnylam Pharmaceuticals's annualized ROC % for the quarter that ended in Mar. 2026 was 75.94%. Alnylam Pharmaceuticals's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was 164.42%.

EBIT is also linked to Joel Greenblatt's definition of earnings yield. Alnylam Pharmaceuticals's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was 2.34%.


Alnylam Pharmaceuticals  (NAS:ALNY) EBIT Explanation

1. EBIT or Operating Income is linked to Return on Capital for both regular definition and Joel Greenblatt's definition.

Alnylam Pharmaceuticals's annualized ROC % for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=1074.544 * ( 1 - 7.07% )/( (1443.297 + 1186.601)/ 2 )
=998.5737392/1314.949
=75.94 %

where

Invested Capital(Q: Dec. 2025 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=4966.331 - 938.721 - ( 2908.484 - max(0, 1466.349 - 4050.662+2908.484))
=1443.297

Invested Capital(Q: Mar. 2026 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=5129.547 - 1073.113 - ( 3009.223 - max(0, 1349.475 - 4219.308+3009.223))
=1186.601

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data.

2. Joel Greenblatt's definition of Return on Capital:

Alnylam Pharmaceuticals's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

ROC (Joel Greenblatt) %(Q: Mar. 2026 )
=EBIT/Average of (Net fixed Assets + Net Working Capital)
=EBIT/Average of (Property, Plant and Equipment+Net Working Capital)
     Q: Dec. 2025  Q: Mar. 2026
=EBIT/( ( (Property, Plant and Equipment + Net Working Capital) + (Property, Plant and Equipment + Net Working Capital) )/ count )
=1163.756/( ( (708.063 + max(-278.653, 0)) + (707.556 + max(-93.729, 0)) )/ 2 )
=1163.756/( ( 708.063 + 707.556 )/ 2 )
=1163.756/707.8095
=164.42 %

where Working Capital is:

Working Capital(Q: Dec. 2025 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(777.567 + 82.719 + 281.892) - (938.721 + 4.845 + 477.265)
=-278.653

Working Capital(Q: Mar. 2026 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(883.957 + 84.025 + 242.103) - (1073.113 + 3.213 + 227.488)
=-93.729

When net working capital is negative, 0 is used.

Note: The EBIT data used here is four times the quarterly (Mar. 2026) EBIT data.

3. It is also linked to Joel Greenblatt's definition of Earnings Yield:

Alnylam Pharmaceuticals's Earnings Yield (Joel Greenblatt) % for today is calculated as:

Earnings Yield (Joel Greenblatt) %=EBIT (TTM)/Enterprise Value (Q: Mar. 2026 )
=869.668/37217.466
=2.34 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Alnylam Pharmaceuticals EBIT Related Terms


Alnylam Pharmaceuticals EBIT Historical Data

* Premium members only.

The historical data trend for Alnylam Pharmaceuticals's EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alnylam Pharmaceuticals EBIT Chart

Alnylam Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -709.12 -971.03 -312.30 -235.52 575.78

Alnylam Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 55.94 4.89 283.37 290.47 290.94

ALNY vs RVMD, ONC, RPRX: EBIT Comparison

For the Biotechnology subindustry, Alnylam Pharmaceuticals's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alnylam Pharmaceuticals EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alnylam Pharmaceuticals's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Alnylam Pharmaceuticals's EV-to-EBIT falls into.


ALNY
74GF Score
Alnylam Pharmaceuticals Inc ALNY
EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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Alnylam Pharmaceuticals EBIT Calculation

EBIT, sometimes also called Earnings Before Interest and Taxes, is a measure of a firm's profit that includes all expenses except interest and income tax expenses. It is the difference between operating revenues and operating expenses. When a firm does not have non-operating income, then Operating Income is sometimes used as a synonym for EBIT and operating profit.

EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $870 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBIT →
What does a EBIT of $870 Mil mean?
Alnylam Pharmaceuticals (ALNY) has a EBIT of $870 Mil as of Mar. 2026. Earnings before interest and taxes is the difference between operating revenue and operating expenses. View historical data on Alnylam Pharmaceuticals.
Is Alnylam Pharmaceuticals' EBIT too high?
Alnylam Pharmaceuticals' current EBIT is $870 Mil. Overall, Alnylam Pharmaceuticals has a GF Score™ of 74/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Alnylam Pharmaceuticals' EBIT compare to RVMD and ONC?
Alnylam Pharmaceuticals' EBIT of $870 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBIT for a Biotechnology company?
A good EBIT depends on the Biotechnology industry context. However, EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBIT mean?
A high EBIT can signal that a stock is expensive relative to its fundamentals. Earnings before interest and taxes is the difference between operating revenue and operating expenses. View historical data on Alnylam Pharmaceuticals. Alnylam Pharmaceuticals's current EBIT is $870 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alnylam Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Alnylam Pharmaceuticals (ALNY) is currently considered Significantly Undervalued. The stock's GF Value™ is $513.74, compared to a current price of $291.76 — trading 43.2% below its estimated fair value. The current EBIT is $870 Mil. Alnylam Pharmaceuticals' overall GF Score™ is 74/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBIT calculated?
EBIT is calculated from a company's financial statements. For Alnylam Pharmaceuticals (ALNY), the current EBIT is $870 Mil as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alnylam Pharmaceuticals (ALNY) Overvalued in 2026?

Based on GuruFocus' analysis, Alnylam Pharmaceuticals stock appears to be undervalued. The current stock price of $291.76 is trading 43.2% below its estimated GF Value™ of $513.74. GuruFocus considers Alnylam Pharmaceuticals to be Significantly Undervalued.

Key valuation signals for ALNY:

  • EBIT: $870 Mil
  • GF Value™: $513.74 vs. price of $291.76 (43.2% below fair value)
  • GF Score™: 74/100 with 3 warning signs

No single metric tells the full story. See the ALNY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alnylam Pharmaceuticals Business Description

Address 675 West Kendall Street, Henri A. Termeer Square, Cambridge, MA, USA, 02142
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
74GF Score

Get the complete analysis for ALNY

EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$291.76
Price
$513.74
GF Value