Avacta GroupLSE:AVCT +0.28%28 EBITDA Margin % is -27,321.05% as of Dec. 2025. GuruFocus rates LSE:AVCT with a GF Score™ of 28/100 and a GF Value™ of £0.49 (Significantly Overvalued). The stock has 8 warning signs investors should review. Among 945 Biotechnology companies, Avacta Group ranks worse than 96.08% on this metric.
EBITDA Margin % is calculated as EBITDA divided by its Revenue. Avacta Group's EBITDA for the
six
months ended in Dec. 2025 was £-15.57 Mil. Avacta Group's Revenue for the
six
months ended in Dec. 2025 was £0.06 Mil. Therefore, Avacta Group's EBITDA margin for the quarter that ended in Dec. 2025 was -27,321.05%.
Avacta Group (LSE:AVCT) EBITDA Margin % Explanation
EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.
Avacta Group EBITDA Margin % Related Terms
Avacta Group EBITDA Margin % Historical Data
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The historical data trend for Avacta Group's EBITDA Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
LSE:AVCT vs VRTX, REGN, ALNY: EBITDA Margin % Comparison
For the Biotechnology subindustry, Avacta Group's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Avacta Group EBITDA Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Avacta Group's EBITDA Margin % distribution charts can be found below:
* The bar in red indicates where Avacta Group's EBITDA Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Avacta Group (LSE:AVCT) has a EBITDA Margin % of -27,321.05% as of Dec. 2025. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Avacta Group and its competitors. According to the industry distribution chart, Avacta Group ranks #908 out of 945 companies in the Biotechnology industry, placing it in the top 96.1%.
Is Avacta Group's EBITDA Margin % too high?
Avacta Group's current EBITDA Margin % is -27,321.05%. Based on the distribution chart, Avacta Group ranks #908 out of 945 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Avacta Group has a GF Score™ of 28/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Avacta Group's EBITDA Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Avacta Group ranks #908 out of 945 companies for EBITDA Margin %. This places Avacta Group in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Avacta Group and its competitors. Avacta Group's current EBITDA Margin % is -27,321.05%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Avacta Group stock overvalued right now?
Based on GuruFocus' analysis, Avacta Group (LSE:AVCT) is currently considered Significantly Overvalued. The stock's GF Value™ is £0.49, compared to a current price of £0.72 — trading 47.3% above its estimated fair value. The current EBITDA Margin % is -27,321.05%. Avacta Group's overall GF Score™ is 28/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Avacta Group (LSE:AVCT), the current EBITDA Margin % is -27,321.05% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Avacta Group (LSE:AVCT) Overvalued in 2026?
Based on GuruFocus' analysis, Avacta Group stock appears to be overvalued.
The current stock price of £0.72 is trading 47.3% above its estimated GF Value™ of £0.49.
GuruFocus considers Avacta Group to be Significantly Overvalued.
Key valuation signals for LSE:AVCT:
EBITDA Margin %: -27,321.05%
GF Value™: £0.49 vs. price of £0.72 (47.3% above fair value)
No single metric tells the full story. See the LSE:AVCT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Avacta Group PLC is a clinical-stage life sciences company expanding the reach of potent cancer therapies with the pre-CISION platform. pre-CISION is a proprietary warhead delivery system based on a tumor-specific protease (fibroblast activation protein or FAP) that is designed to concentrate potent warheads in the tumor microenvironment while sparing normal tissues. The company's pipeline consists of pre-CISION peptide drug conjugates (PDC) or Affimer drug conjugates (AffDC) that leverage the tumor-specific release mechanism, providing benefits over traditional antibody drug conjugates. The firm has one reportable segment, Therapeutics, which is engaged in the development of novel cancer therapies harnessing its proprietary technology. Geographically, it derives revenue from South Korea.
28GF Score
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