Avacta Group (LSE:AVCT) ROA %: -142.42% (As of Dec. 2025)


LSE:AVCT Avacta Group PLC LSE:AVCT
28 GF Score
Price £0.72
GF Value £0.49
Valuation Significantly Overvalued
! 8 Warning Signs
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What is Avacta Group ROA %?

Avacta Group LSE:AVCT +0.28% 28 ROA % is -142.42% as of Dec. 2025. GuruFocus rates LSE:AVCT with a GF Score™ of 28/100 and a GF Value™ of £0.49 (Significantly Overvalued). The stock has 8 warning signs investors should review. Among 1,423 Biotechnology companies, Avacta Group ranks worse than 84.4% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Avacta Group's annualized Net Income for the quarter that ended in Dec. 2025 was £-41.77 Mil. Avacta Group's average Total Assets over the quarter that ended in Dec. 2025 was £29.33 Mil. Therefore, Avacta Group's annualized ROA % for the quarter that ended in Dec. 2025 was -142.42%.

The historical rank and industry rank for Avacta Group's ROA % or its related term are showing as below:

LSE:AVCT' s ROA % Range Over the Past 10 Years
Min: -108.33   Med: -40.8   Max: -15.76
Current: -108.33

During the past 13 years, Avacta Group's highest ROA % was -15.76%. The lowest was -108.33%. And the median was -40.80%.

LSE:AVCT's ROA % is ranked worse than
84.4% of 1423 companies
in the Biotechnology industry
Industry Median: -33.07 vs LSE:AVCT: -108.33

Avacta Group  (LSE:AVCT) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=-41.768/29.327
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-41.768 / 0.114)*(0.114 / 29.327)
=Net Margin %*Asset Turnover
=-36638.6 %*0.0039
=-142.42 %

Note: The Net Income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Avacta Group ROA % Related Terms


Avacta Group ROA % Historical Data

* Premium members only.

The historical data trend for Avacta Group's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Avacta Group ROA % Chart

Avacta Group Annual Data
Trend Jul15 Jul16 Jul17 Jul18 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -45.98 -52.36 -40.04 -87.01 -99.40

Avacta Group Semi-Annual Data
Jul15 Jan16 Jul16 Jan17 Jul17 Jan18 Jul18 Jan19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -53.99 -19.61 -130.49 -91.49 -142.42

LSE:AVCT vs VRTX, REGN, ALNY: ROA % Comparison

For the Biotechnology subindustry, Avacta Group's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Avacta Group ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Avacta Group's ROA % distribution charts can be found below:

* The bar in red indicates where Avacta Group's ROA % falls into.


LSE:AVCT
28GF Score
Avacta Group PLC LSE:AVCT
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Avacta Group ROA % Calculation

Avacta Group's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-38.612/( (48.27+29.417)/ 2 )
=-38.612/38.8435
=-99.40 %

Avacta Group's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=-41.768/( (29.237+29.417)/ 2 )
=-41.768/29.327
=-142.42 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is two times the semi-annual (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -142.42% mean?
Avacta Group (LSE:AVCT) has a ROA % of -142.42% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Avacta Group and its competitors. According to the industry distribution chart, Avacta Group ranks #1201 out of 1423 companies in the Biotechnology industry, placing it in the top 84.4%.
Is Avacta Group's ROA % too high?
Avacta Group's current ROA % is -142.42%. Based on the distribution chart, Avacta Group ranks #1201 out of 1423 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Avacta Group has a GF Score™ of 28/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Avacta Group's ROA % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Avacta Group ranks #1201 out of 1423 companies for ROA %. This places Avacta Group in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Avacta Group and its competitors. Avacta Group's current ROA % is -142.42%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Avacta Group stock overvalued right now?
Based on GuruFocus' analysis, Avacta Group (LSE:AVCT) is currently considered Significantly Overvalued. The stock's GF Value™ is £0.49, compared to a current price of £0.72 — trading 47.3% above its estimated fair value. The current ROA % is -142.42%. Avacta Group's overall GF Score™ is 28/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Avacta Group (LSE:AVCT), the current ROA % is -142.42% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Avacta Group (LSE:AVCT) Overvalued in 2026?

Based on GuruFocus' analysis, Avacta Group stock appears to be overvalued. The current stock price of £0.72 is trading 47.3% above its estimated GF Value™ of £0.49. GuruFocus considers Avacta Group to be Significantly Overvalued.

Key valuation signals for LSE:AVCT:

  • ROA %: -142.42%
  • GF Value™: £0.49 vs. price of £0.72 (47.3% above fair value)
  • GF Score™: 28/100 with 8 warning signs

No single metric tells the full story. See the LSE:AVCT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Avacta Group Business Description

Other Exchanges AVCTF:USARTQ1:Germany
Address 58 Wood Lane, White City Imperial College Campus, Scale Space, London, GBR, W12 7RZ
Avacta Group PLC is a clinical-stage life sciences company expanding the reach of potent cancer therapies with the pre-CISION platform. pre-CISION is a proprietary warhead delivery system based on a tumor-specific protease (fibroblast activation protein or FAP) that is designed to concentrate potent warheads in the tumor microenvironment while sparing normal tissues. The company's pipeline consists of pre-CISION peptide drug conjugates (PDC) or Affimer drug conjugates (AffDC) that leverage the tumor-specific release mechanism, providing benefits over traditional antibody drug conjugates. The firm has one reportable segment, Therapeutics, which is engaged in the development of novel cancer therapies harnessing its proprietary technology. Geographically, it derives revenue from South Korea.
28GF Score

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ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£0.72
Price
£0.49
GF Value