ISLMF (InSilico Medicine Cayman TopCo) EBITDA per Share: $-4.23 (TTM As of Dec. 2025)

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ISLMF InSilico Medicine Cayman TopCo ISLMF
13 GF Score
Price $6.11
! 3 Warning Signs
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What is InSilico Medicine Cayman TopCo EBITDA per Share?

InSilico Medicine Cayman TopCo ISLMF -1.77% 13 EBITDA per Share is $-4.23 as of Dec. 2025. GuruFocus rates ISLMF with a GF Score™ of 13/100. The stock has 3 warning signs investors should review. Among 2,071 Software companies, InSilico Medicine Cayman TopCo ranks worse than 98.74% on this metric.

InSilico Medicine Cayman TopCo's EBITDA per Share for the three months ended in Dec. 2025 was $-4.20. Its EBITDA per Share for the trailing twelve months (TTM) ended in Dec. 2025 was $-4.23.

During the past 3 years, the average EBITDA per Share Growth Rate was -123.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA per Share growth rate using EBITDA per Share data.

The historical rank and industry rank for InSilico Medicine Cayman TopCo's EBITDA per Share or its related term are showing as below:

ISLMF' s 3-Year EBITDA Growth Rate Range Over the Past 10 Years
Min: -123.6   Med: -123.6   Max: -123.6
Current: -123.6

During the past 4 years, the highest 3-Year average EBITDA per Share Growth Rate of InSilico Medicine Cayman TopCo was -123.60% per year. The lowest was -123.60% per year. And the median was -123.60% per year.

ISLMF's 3-Year EBITDA Growth Rate is ranked worse than
98.74% of 2071 companies
in the Software industry
Industry Median: 12.2 vs ISLMF: -123.60

InSilico Medicine Cayman TopCo's EBITDA for the three months ended in Dec. 2025 was $-330.47 Mil.

During the past 3 years, the average EBITDA Growth Rate was -16.40% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA Growth Rate using EBITDA data.

During the past 4 years, the highest 3-Year average EBITDA Growth Rate of InSilico Medicine Cayman TopCo was -16.40% per year. The lowest was -16.40% per year. And the median was -16.40% per year.


InSilico Medicine Cayman TopCo  (OTCPK:ISLMF) EBITDA per Share Explanation

EBITDA is a cash flow measure that ignores changes in working capital. EBITDA minus Depreciation, and Amortization (DA) equals EBIT. EBIT is profit before interest and taxes. Of course, Interest and taxes need to be paid.

While depreciation and amortization expenses do not need to be paid in cash, assets - especially tangible assets - do need to be replaced over time. EBITDA is not a measure of profit in any sense. EBITDA is a measure of cash generation by a business where the uses of that cash may be more or less discretionary depending on the nature of the business.

The EBITDA of a TV station is largely discretionary. Owners may use much of the EBITDA generated by a TV station as they see fit. The EBITDA of a railroad is largely non-discretionary. Owners must use much of the EBITDA generated by a railroad to replace the physical assets of the railroad or the business will literally fall apart over time.

EBITDA can be thought of as the cash a business generates that is available to:

Add more inventory
Add more receivables
Replace property, plant, and equipment
Add more property, plant, and equipment
Pay interest
Pay taxes
And finally: pay owners

EBITDA is widely used in financial analysis because Depreciation and Amortization are not present day cash expenses. Depreciation and amortization are the spreading out of the costs of assets over the time in which those assets provide benefits. Today's depreciation and amortization expenses relate to assets bought in the past. The assets being expensed may or may not need to be replaced in the future. And the cost to replace the assets may be more or less than it was in the past. For this reason, the depreciation and amortization expenses a company records in the present year may have no relationship to the actual cash costs needed to maintain its assets in future years.

A company's depreciation expense depends on both its expectations about the assets it owns and its choice of accounting methods. Two companies owning identical assets may have different depreciation expenses because they have different expectations about the useful lives of those assets and because they make different accounting choices.

Analysts use EBITDA to remove this element of personal choice from a company's accounting statements. The use of EBITDA is an attempt to make the results of different companies more comparable and uniform.


Be Aware

Although depreciation is not a cash cost, it is a real business cost because the company has to pay for the fixed assets when they purchase them. Both Warren Buffett and Charlie Munger hate the idea of EBITDA because in this calculation, depreciation is not counted as an expense.

EBITDA over Revenue is a good metric for comparing the operating efficiencies between companies because EBITDA is less vulnerable to companies' accounting choices. For this reason, EBITDA is used in ranking the Predictability of Companies.


InSilico Medicine Cayman TopCo EBITDA per Share Related Terms


InSilico Medicine Cayman TopCo EBITDA per Share Historical Data

* Premium members only.

The historical data trend for InSilico Medicine Cayman TopCo's EBITDA per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

InSilico Medicine Cayman TopCo EBITDA per Share Chart

InSilico Medicine Cayman TopCo Annual Data
Trend Dec22 Dec23 Dec24 Dec25
EBITDA per Share
-0.40 -0.37 -0.02 -4.41

InSilico Medicine Cayman TopCo Quarterly Data
Dec22 Dec23 Jun24 Dec24 Jun25 Dec25
EBITDA per Share Get a 7-Day Free Trial 0.00 0.02 -0.04 -0.03 -4.20
ISLMF
13GF Score
InSilico Medicine Cayman TopCo ISLMF
EBITDA per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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InSilico Medicine Cayman TopCo EBITDA per Share Calculation

EBITDA per Share is the amount of Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) per outstanding share of the company's stock.

Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) is what the company earns before it expenses interest, taxes, depreciation and amortization.

InSilico Medicine Cayman TopCo's EBITDA per Share for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA per Share(A: Dec. 2025 )
=EBITDA/Shares Outstanding (Diluted Average)
=-347.273/78.705
=-4.41

InSilico Medicine Cayman TopCo's EBITDA per Share for the quarter that ended in Dec. 2025 is calculated as

EBITDA per Share(Q: Dec. 2025 )
=EBITDA/Shares Outstanding (Diluted Average)
=-330.47/78.705
=-4.20

EBITDA per Share for the trailing twelve months (TTM) ended in Dec. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-4.23

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA per Share →
What does a EBITDA per Share of $-4.23 mean?
InSilico Medicine Cayman TopCo (ISLMF) has a EBITDA per Share of $-4.23 as of Dec. 2025. EBITDA per share is the per-share amount of earnings before interest, taxes, depreciation and amortization. View historical data on InSilico Medicine Cayman TopCo and its competitors. According to the industry distribution chart, InSilico Medicine Cayman TopCo ranks #2045 out of 2071 companies in the Software industry, placing it in the top 98.7%.
Is InSilico Medicine Cayman TopCo's EBITDA per Share too high?
InSilico Medicine Cayman TopCo's current EBITDA per Share is $-4.23. Based on the distribution chart, InSilico Medicine Cayman TopCo ranks #2045 out of 2071 companies in the Software industry, which is in the bottom quartile relative to peers. Overall, InSilico Medicine Cayman TopCo has a GF Score™ of 13/100, reflecting its overall financial health beyond just this single metric.
How does InSilico Medicine Cayman TopCo's EBITDA per Share compare to ?
According to the Software industry distribution chart, InSilico Medicine Cayman TopCo ranks #2045 out of 2071 companies for EBITDA per Share. This places InSilico Medicine Cayman TopCo in the lower half of its industry. The industry median EBITDA per Share is 12.20. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA per Share for a Software company?
The median EBITDA per Share among Software companies is 12.20, based on 2,071 companies in the industry. Companies in the top quartile (top 25%) have a EBITDA per Share significantly above this median, while those in the bottom quartile fall well below. However, EBITDA per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA per Share mean?
A high EBITDA per Share can signal that a stock is expensive relative to its fundamentals. EBITDA per share is the per-share amount of earnings before interest, taxes, depreciation and amortization. View historical data on InSilico Medicine Cayman TopCo and its competitors. For the Software industry, the median EBITDA per Share is 12.20 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. InSilico Medicine Cayman TopCo's current EBITDA per Share is $-4.23. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is InSilico Medicine Cayman TopCo stock overvalued right now?
InSilico Medicine Cayman TopCo (ISLMF) has a current EBITDA per Share of $-4.23. The current EBITDA per Share is $-4.23. InSilico Medicine Cayman TopCo's overall GF Score™ is 13/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA per Share calculated?
EBITDA per Share is calculated from a company's financial statements. For InSilico Medicine Cayman TopCo (ISLMF), the current EBITDA per Share is $-4.23 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

InSilico Medicine Cayman TopCo Business Description

Comparable Companies
Other Exchanges 03696:Hong KongO15:Germany
Address Hong Kong Science Park, Unit 310, 3rd Floor, Building 8W, Phase 2, Pak Shek Kok, New Territories, Hong Kong, HKG
InSilico Medicine Cayman TopCo is engaged in applying artificial intelligence (AI) solutions to drug discovery and development by leveraging its proprietary platforms. It has generated multiple clinical-stage or IND-enabling assets using Pharma.AI, an AI-enabled platform that supports drug discovery and development activities. The company operates under a project-based business model, deriving revenue from out-licensing and collaboration arrangements. Geographically, the company generates revenue from multiple countries, with the majority of the revenue coming from United States.
13GF Score

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EBITDA per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$6.11
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