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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, InSilico Medicine Cayman TopCo's enterprise value is $2,918.41 Mil.
InSilico Medicine Cayman TopCo's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was $-347.27 Mil. Therefore, InSilico Medicine Cayman TopCo's EV-to-EBITDA for today is -8.40.
The historical rank and industry rank for InSilico Medicine Cayman TopCo's EV-to-EBITDA or its related term are showing as below:
ISLMF'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -8.83 Med: -0.27 Max: 0.29
Current: -8.4
During the past 4 years, the highest EV-to-EBITDA of InSilico Medicine Cayman TopCo was 0.29. The lowest was -8.83. And the median was -0.27.
ISLMF's EV-to-EBITDA is ranked worse than 100% of 1969
companies
in the Software industry
Industry Median: 10.35
vs ISLMF: -8.40
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
InSilico Medicine Cayman TopCo (OTCPK:ISLMF) EV-to-EBITDA Explanation
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
InSilico Medicine Cayman TopCo's PE Ratio (TTM) for today is calculated as:
InSilico Medicine Cayman TopCo's share price for today is $6.11.
InSilico Medicine Cayman TopCo's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $0.000.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Software - Infrastructure subindustry, InSilico Medicine Cayman TopCo's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
InSilico Medicine Cayman TopCo EV-to-EBITDA vs Software Industry
For the Software industry and Technology sector, InSilico Medicine Cayman TopCo's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where InSilico Medicine Cayman TopCo's EV-to-EBITDA falls into.
InSilico Medicine Cayman TopCo's current Enterprise Value is $2,918.41 Mil.
InSilico Medicine Cayman TopCo's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-347.27 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
InSilico Medicine Cayman TopCo (ISLMF) has a EV-to-EBITDA of -8.40 as of Aug. 27, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on InSilico Medicine Cayman TopCo. According to the industry distribution chart, InSilico Medicine Cayman TopCo ranks #999999 out of 1969 companies in the Software industry.
Is InSilico Medicine Cayman TopCo's EV-to-EBITDA too high?
InSilico Medicine Cayman TopCo's current EV-to-EBITDA is -8.40. Based on the distribution chart, InSilico Medicine Cayman TopCo ranks #999999 out of 1969 companies in the Software industry, which is in the bottom quartile relative to peers. Overall, InSilico Medicine Cayman TopCo has a GF Score™ of 13/100, reflecting its overall financial health beyond just this single metric.
How does InSilico Medicine Cayman TopCo's EV-to-EBITDA compare to ?
According to the Software industry distribution chart, InSilico Medicine Cayman TopCo ranks #999999 out of 1969 companies for EV-to-EBITDA. This places InSilico Medicine Cayman TopCo in the lower half of its industry. The industry median EV-to-EBITDA is 10.35. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Software company?
The median EV-to-EBITDA among Software companies is 10.35, based on 1,969 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on InSilico Medicine Cayman TopCo. For the Software industry, the median EV-to-EBITDA is 10.35 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. InSilico Medicine Cayman TopCo's current EV-to-EBITDA is -8.40. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is InSilico Medicine Cayman TopCo stock overvalued right now?
InSilico Medicine Cayman TopCo (ISLMF) has a current EV-to-EBITDA of -8.40. The current EV-to-EBITDA is -8.40. InSilico Medicine Cayman TopCo's overall GF Score™ is 13/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For InSilico Medicine Cayman TopCo (ISLMF), the current EV-to-EBITDA is -8.40 as of Aug. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
InSilico Medicine Cayman TopCo is engaged in applying artificial intelligence (AI) solutions to drug discovery and development by leveraging its proprietary platforms. It has generated multiple clinical-stage or IND-enabling assets using Pharma.AI, an AI-enabled platform that supports drug discovery and development activities. The company operates under a project-based business model, deriving revenue from out-licensing and collaboration arrangements. Geographically, the company generates revenue from multiple countries, with the majority of the revenue coming from United States.
13GF Score
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