APRE (Aprea Therapeutics) EV-to-EBIT: 3.00 (As of Jul. 19, 2026)

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APRE Aprea Therapeutics Inc APRE
30 GF Score
Price $0.71
! 1 Warning Sign
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What is Aprea Therapeutics EV-to-EBIT?

Aprea Therapeutics APRE +2.86% 30 EV-to-EBIT is 3.00 as of Jul. 19, 2026. GuruFocus rates APRE with a GF Score™ of 30/100. The stock has 1 warning sign investors should review. Among 372 Biotechnology companies, Aprea Therapeutics ranks better than 69.35% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Aprea Therapeutics's Enterprise Value is $-37.68 Mil. Aprea Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-12.58 Mil. Therefore, Aprea Therapeutics's EV-to-EBIT for today is 3.00.

The historical rank and industry rank for Aprea Therapeutics's EV-to-EBIT or its related term are showing as below:

APRE' s EV-to-EBIT Range Over the Past 10 Years
Min: 0   Med: 0   Max: 3
Current: 3

During the past 9 years, the highest EV-to-EBIT of Aprea Therapeutics was 3.00. The lowest was 0.00. And the median was 0.00.

APRE's EV-to-EBIT is ranked better than
69.35% of 372 companies
in the Biotechnology industry
Industry Median: 13.255 vs APRE: 3.00

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Aprea Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $-37.32 Mil. Aprea Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-12.58 Mil. Aprea Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was 33.70%.


Aprea Therapeutics  (NAS:APRE) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Aprea Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-12.578/-37.3241693
=33.70 %

Aprea Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $-37.32 Mil.
Aprea Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-12.58 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Aprea Therapeutics EV-to-EBIT Related Terms


Aprea Therapeutics EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Aprea Therapeutics's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Aprea Therapeutics EV-to-EBIT Chart

Aprea Therapeutics Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only -0.26 0.30 0.26 0.34 0.58

Aprea Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.53 0.46 0.35 0.58 2.97

APRE vs JSPR, CVKD, BRTX: EV-to-EBIT Comparison

For the Biotechnology subindustry, Aprea Therapeutics's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Aprea Therapeutics EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Aprea Therapeutics's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Aprea Therapeutics's EV-to-EBIT falls into.


APRE
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Aprea Therapeutics Inc APRE
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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Aprea Therapeutics EV-to-EBIT Calculation

Aprea Therapeutics's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=-37.681/-12.578
=3.00

Aprea Therapeutics's current Enterprise Value is $-37.68 Mil.
Aprea Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-12.58 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of 3.00 mean?
Aprea Therapeutics (APRE) has a EV-to-EBIT of 3.00 as of Jul. 19, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Aprea Therapeutics and its competitors. According to the industry distribution chart, Aprea Therapeutics ranks #114 out of 372 companies in the Biotechnology industry, placing it in the top 30.6%.
Is Aprea Therapeutics' EV-to-EBIT too high?
Aprea Therapeutics' current EV-to-EBIT is 3.00. The Biotechnology industry median EV-to-EBIT is 13.26. Aprea Therapeutics' value of 3.00 is 77.4% below this industry median. Based on the distribution chart, Aprea Therapeutics ranks #114 out of 372 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Aprea Therapeutics has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Aprea Therapeutics' EV-to-EBIT compare to JSPR and CVKD?
According to the Biotechnology industry distribution chart, Aprea Therapeutics ranks #114 out of 372 companies for EV-to-EBIT. This puts Aprea Therapeutics in the upper half of its industry. The industry median EV-to-EBIT is 13.26. Aprea Therapeutics' value of 3.00 is 77.4% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 13.26, based on 372 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Aprea Therapeutics's current EV-to-EBIT of 3.00 is 77.4% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Aprea Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 13.26 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Aprea Therapeutics's current EV-to-EBIT is 3.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Aprea Therapeutics stock overvalued right now?
Aprea Therapeutics (APRE) has a current EV-to-EBIT of 3.00. The current EV-to-EBIT is 3.00 and 77.4% below the Biotechnology industry median of 13.26. Aprea Therapeutics' overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Aprea Therapeutics (APRE), the current EV-to-EBIT is 3.00 as of Jul. 19, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Aprea Therapeutics Business Description

Address 3805 Old Easton Road, Doylestown, PA, USA, 18902
Aprea Therapeutics Inc is a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers. It develops small molecule inhibitors designed to exploit genetic mutations in cancer to widen the therapeutic window and is intended to make treatments more effective at destroying cancer cells while sparing healthy tissue. The company's pipeline of clinical and preclinical programs includes APR-1051, a WEE1 inhibitor; ATRN-119 (Mosipasertib), an oral small molecule inhibitor of ataxia telangiectasia and Rad3-related, or ATR; and an early-stage program, APR-1602. These candidates are being developed for broad applications in cancer treatment.
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