ENSC (Ensysce Biosciences) EV-to-EBIT: -0.29 (As of Jul. 14, 2026)

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ENSC Ensysce Biosciences Inc ENSC
23 GF Score
Price $0.27
! 2 Warning Signs
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What is Ensysce Biosciences EV-to-EBIT?

Ensysce Biosciences ENSC +2.44% 23 EV-to-EBIT is -0.29 as of Jul. 14, 2026. GuruFocus rates ENSC with a GF Score™ of 23/100. The stock has 2 warning signs investors should review. Among 371 Biotechnology companies, Ensysce Biosciences ranks worse than 269541.51% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Ensysce Biosciences's Enterprise Value is $3.36 Mil. Ensysce Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-11.77 Mil. Therefore, Ensysce Biosciences's EV-to-EBIT for today is -0.29.

The historical rank and industry rank for Ensysce Biosciences's EV-to-EBIT or its related term are showing as below:

ENSC' s EV-to-EBIT Range Over the Past 10 Years
Min: -0.29   Med: 0   Max: 0
Current: -0.29

ENSC's EV-to-EBIT is ranked worse than
100% of 371 companies
in the Biotechnology industry
Industry Median: 13.76 vs ENSC: -0.29

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Ensysce Biosciences's Enterprise Value for the quarter that ended in Mar. 2026 was $4.17 Mil. Ensysce Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-11.77 Mil. Ensysce Biosciences's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -282.33%.


Ensysce Biosciences  (NAS:ENSC) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Ensysce Biosciences's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-11.768/4.168203
=-282.33 %

Ensysce Biosciences's Enterprise Value for the quarter that ended in Mar. 2026 was $4.17 Mil.
Ensysce Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-11.77 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Ensysce Biosciences EV-to-EBIT Related Terms


Ensysce Biosciences EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Ensysce Biosciences's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ensysce Biosciences EV-to-EBIT Chart

Ensysce Biosciences Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial -4.42 -0.24 -0.27 -1.12 0.01

Ensysce Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.16 -0.49 -0.54 0.01 -0.35

ENSC vs RNAZ, ALZN, CELZ: EV-to-EBIT Comparison

For the Biotechnology subindustry, Ensysce Biosciences's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ensysce Biosciences EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ensysce Biosciences's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Ensysce Biosciences's EV-to-EBIT falls into.


ENSC
23GF Score
Ensysce Biosciences Inc ENSC
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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Ensysce Biosciences EV-to-EBIT Calculation

Ensysce Biosciences's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=3.363/-11.768
=-0.29

Ensysce Biosciences's current Enterprise Value is $3.36 Mil.
Ensysce Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-11.77 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -0.29 mean?
Ensysce Biosciences (ENSC) has a EV-to-EBIT of -0.29 as of Jul. 14, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Ensysce Biosciences and its competitors. According to the industry distribution chart, Ensysce Biosciences ranks #999999 out of 371 companies in the Biotechnology industry.
Is Ensysce Biosciences' EV-to-EBIT too high?
Ensysce Biosciences' current EV-to-EBIT is -0.29. Based on the distribution chart, Ensysce Biosciences ranks #999999 out of 371 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Ensysce Biosciences has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Ensysce Biosciences' EV-to-EBIT compare to RNAZ and ALZN?
According to the Biotechnology industry distribution chart, Ensysce Biosciences ranks #999999 out of 371 companies for EV-to-EBIT. This places Ensysce Biosciences in the lower half of its industry. The industry median EV-to-EBIT is 13.76. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 13.76, based on 371 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Ensysce Biosciences and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 13.76 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Ensysce Biosciences's current EV-to-EBIT is -0.29. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ensysce Biosciences stock overvalued right now?
Ensysce Biosciences (ENSC) has a current EV-to-EBIT of -0.29. The current EV-to-EBIT is -0.29. Ensysce Biosciences' overall GF Score™ is 23/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Ensysce Biosciences (ENSC), the current EV-to-EBIT is -0.29 as of Jul. 14, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Ensysce Biosciences Business Description

Address 7946 Ivanhoe Avenue, Suite 201, La Jolla, CA, USA, 92037
Ensysce Biosciences Inc is a clinical-stage biotech company using its proprietary technology platforms to develop safer prescription drugs. The company is developing a new class of powerful, opioids that prevent both drug abuse and overdoses. Its products are anticipated to provide safer options to treat severe pain and assist in preventing deaths caused by opioid abuse, reducing human and economic costs. The company's current development pipeline includes two new drug platforms: an abuse-resistant opioid prodrug technology, theTrypsin Activated Abuse Protection, or the TAAP platform, and an over-dose protection opioid prodrug technology, the Multi-Pill Abuse Resistant, or the MPAR platform. The Company currently operates in one business segment, which is pharmaceuticals.
23GF Score

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EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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