OKUR (OnKure Therapeutics) EV-to-EBIT: 0.31 (As of Aug. 24, 2026)

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OKUR OnKure Therapeutics Inc OKUR
14 GF Score
Price $3.81
! 2 Warning Signs
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What is OnKure Therapeutics EV-to-EBIT?

OnKure Therapeutics OKUR -3.30% 14 EV-to-EBIT is 0.31 as of Aug. 24, 2026. GuruFocus rates OKUR with a GF Score™ of 14/100. The stock has 2 warning signs investors should review. Among 377 Biotechnology companies, OnKure Therapeutics ranks better than 91.78% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, OnKure Therapeutics's Enterprise Value is $-18.55 Mil. OnKure Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was $-60.71 Mil. Therefore, OnKure Therapeutics's EV-to-EBIT for today is 0.31.

The historical rank and industry rank for OnKure Therapeutics's EV-to-EBIT or its related term are showing as below:

OKUR' s EV-to-EBIT Range Over the Past 10 Years
Min: 0   Med: 0   Max: 0.37
Current: 0.31

During the past 4 years, the highest EV-to-EBIT of OnKure Therapeutics was 0.37. The lowest was 0.00. And the median was 0.00.

OKUR's EV-to-EBIT is ranked better than
91.78% of 377 companies
in the Biotechnology industry
Industry Median: 16.02 vs OKUR: 0.31

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. OnKure Therapeutics's Enterprise Value for the quarter that ended in Jun. 2026 was $9.20 Mil. OnKure Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was $-60.71 Mil. OnKure Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 was -659.74%.


OnKure Therapeutics  (NAS:OKUR) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

OnKure Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Jun. 2026 ) =EBIT / Enterprise Value (Q: Jun. 2026 )
=-60.708/9.20176
=-659.74 %

OnKure Therapeutics's Enterprise Value for the quarter that ended in Jun. 2026 was $9.20 Mil.
OnKure Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-60.71 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


OnKure Therapeutics EV-to-EBIT Related Terms


OnKure Therapeutics EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for OnKure Therapeutics's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OnKure Therapeutics EV-to-EBIT Chart

OnKure Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
0.00 0.00 -0.10 0.32

OnKure Therapeutics Quarterly Data
Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.81 0.50 0.32 0.41 -0.15

OKUR vs CRBP, HUMA, ARMP: EV-to-EBIT Comparison

For the Biotechnology subindustry, OnKure Therapeutics's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OnKure Therapeutics EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OnKure Therapeutics's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where OnKure Therapeutics's EV-to-EBIT falls into.


OKUR
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OnKure Therapeutics Inc OKUR
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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OnKure Therapeutics EV-to-EBIT Calculation

OnKure Therapeutics's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=-18.553/-60.708
=0.31

OnKure Therapeutics's current Enterprise Value is $-18.55 Mil.
OnKure Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-60.71 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of 0.31 mean?
OnKure Therapeutics (OKUR) has a EV-to-EBIT of 0.31 as of Aug. 24, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on OnKure Therapeutics and its competitors. According to the industry distribution chart, OnKure Therapeutics ranks #31 out of 377 companies in the Biotechnology industry, placing it in the top 8.2%.
Is OnKure Therapeutics' EV-to-EBIT too high?
OnKure Therapeutics' current EV-to-EBIT is 0.31. The Biotechnology industry median EV-to-EBIT is 16.02. OnKure Therapeutics' value of 0.31 is 98.1% below this industry median. Based on the distribution chart, OnKure Therapeutics ranks #31 out of 377 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, OnKure Therapeutics has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does OnKure Therapeutics' EV-to-EBIT compare to CRBP and HUMA?
According to the Biotechnology industry distribution chart, OnKure Therapeutics ranks #31 out of 377 companies for EV-to-EBIT. This places OnKure Therapeutics in the top 8% of its industry — outperforming the majority of peers. The industry median EV-to-EBIT is 16.02. OnKure Therapeutics' value of 0.31 is 98.1% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 16.02, based on 377 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. OnKure Therapeutics's current EV-to-EBIT of 0.31 is 98.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on OnKure Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 16.02 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OnKure Therapeutics's current EV-to-EBIT is 0.31. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OnKure Therapeutics stock overvalued right now?
OnKure Therapeutics (OKUR) has a current EV-to-EBIT of 0.31. The current EV-to-EBIT is 0.31 and 98.1% below the Biotechnology industry median of 16.02. OnKure Therapeutics' overall GF Score™ is 14/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For OnKure Therapeutics (OKUR), the current EV-to-EBIT is 0.31 as of Aug. 24, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

OnKure Therapeutics Business Description

Address 6707 Winchester Circle, Suite 400, Boulder, CO, USA, 80301
OnKure Therapeutics Inc is a clinical-stage biopharmaceutical company focused on discovering and developing precision medicines that target biologically validated drivers of cancers underserved by available therapies. The company uses a structure-based drug design platform to develop a pipeline of drug candidates aimed at optimizing efficacy and tolerability. The company has multiple programs focused on targeting oncogenic PI3K?. Its flagship program is OKI-219. The company operates in one operating segment: clinical research.
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