XFOR (X4 Pharmaceuticals) EV-to-EBIT: -2.42 (As of Jul. 07, 2026)


XFOR X4 Pharmaceuticals Inc XFOR
24 GF Score
Price $3.99
! 6 Warning Signs
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What is X4 Pharmaceuticals EV-to-EBIT?

X4 Pharmaceuticals XFOR -1.12% 24 EV-to-EBIT is -2.42 as of Jul. 07, 2026. GuruFocus rates XFOR with a GF Score™ of 24/100. The stock has 6 warning signs investors should review. Among 365 Biotechnology companies, X4 Pharmaceuticals ranks worse than 273972.33% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, X4 Pharmaceuticals's Enterprise Value is $219.87 Mil. X4 Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-90.91 Mil. Therefore, X4 Pharmaceuticals's EV-to-EBIT for today is -2.42.

The historical rank and industry rank for X4 Pharmaceuticals's EV-to-EBIT or its related term are showing as below:

XFOR' s EV-to-EBIT Range Over the Past 10 Years
Min: -12.58   Med: -0.39   Max: 3.26
Current: -2.42

During the past 11 years, the highest EV-to-EBIT of X4 Pharmaceuticals was 3.26. The lowest was -12.58. And the median was -0.39.

XFOR's EV-to-EBIT is ranked worse than
100% of 365 companies
in the Biotechnology industry
Industry Median: 14.69 vs XFOR: -2.42

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. X4 Pharmaceuticals's Enterprise Value for the quarter that ended in Mar. 2026 was $233.07 Mil. X4 Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-90.91 Mil. X4 Pharmaceuticals's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -39.00%.


X4 Pharmaceuticals  (NAS:XFOR) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

X4 Pharmaceuticals's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-90.906/233.0746
=-39.00 %

X4 Pharmaceuticals's Enterprise Value for the quarter that ended in Mar. 2026 was $233.07 Mil.
X4 Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-90.91 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


X4 Pharmaceuticals EV-to-EBIT Related Terms


X4 Pharmaceuticals EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for X4 Pharmaceuticals's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

X4 Pharmaceuticals EV-to-EBIT Chart

X4 Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -0.26 -0.42 -0.89 -3.57 -2.67

X4 Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.34 -0.33 -0.48 -2.67 -2.56

XFOR vs CMPX, LRMR, PROK: EV-to-EBIT Comparison

For the Biotechnology subindustry, X4 Pharmaceuticals's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


X4 Pharmaceuticals EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, X4 Pharmaceuticals's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where X4 Pharmaceuticals's EV-to-EBIT falls into.


XFOR
24GF Score
X4 Pharmaceuticals Inc XFOR
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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X4 Pharmaceuticals EV-to-EBIT Calculation

X4 Pharmaceuticals's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=219.869/-90.906
=-2.42

X4 Pharmaceuticals's current Enterprise Value is $219.87 Mil.
X4 Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-90.91 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -2.42 mean?
X4 Pharmaceuticals (XFOR) has a EV-to-EBIT of -2.42 as of Jul. 07, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on X4 Pharmaceuticals and its competitors. According to the industry distribution chart, X4 Pharmaceuticals ranks #999999 out of 365 companies in the Biotechnology industry.
Is X4 Pharmaceuticals' EV-to-EBIT too high?
X4 Pharmaceuticals' current EV-to-EBIT is -2.42. Based on the distribution chart, X4 Pharmaceuticals ranks #999999 out of 365 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, X4 Pharmaceuticals has a GF Score™ of 24/100, reflecting its overall financial health beyond just this single metric.
How does X4 Pharmaceuticals' EV-to-EBIT compare to CMPX and LRMR?
According to the Biotechnology industry distribution chart, X4 Pharmaceuticals ranks #999999 out of 365 companies for EV-to-EBIT. This places X4 Pharmaceuticals in the lower half of its industry. The industry median EV-to-EBIT is 14.69. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 14.69, based on 365 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on X4 Pharmaceuticals and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 14.69 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. X4 Pharmaceuticals's current EV-to-EBIT is -2.42. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is X4 Pharmaceuticals stock overvalued right now?
X4 Pharmaceuticals (XFOR) has a current EV-to-EBIT of -2.42. The current EV-to-EBIT is -2.42. X4 Pharmaceuticals' overall GF Score™ is 24/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For X4 Pharmaceuticals (XFOR), the current EV-to-EBIT is -2.42 as of Jul. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

X4 Pharmaceuticals Business Description

Address 61 North Beacon Street, 4th Floor, Boston, MA, USA, 02134
X4 Pharmaceuticals Inc is a biopharmaceutical company developing and commercializing novel therapeutics for the treatment of rare hematology diseases. The Company's clinical candidate is mavorixafor, a small molecule antagonist of the chemokine receptor CXCR4 that is being developed as an oral, once-daily therapy. It can increase the mobilization of mature, functional white blood cells from the bone marrow into the bloodstream. It also has two pre-clinical candidates X4P-003 and X4P-002 which are CXCR4 antagonists with different properties.
24GF Score

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EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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