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X4 PharmaceuticalsXFOR -1.79%24 3-Year Share Buyback Ratio is -181.90 as of Mar. 2026. GuruFocus rates XFOR with a GF Score™ of 24/100. The stock has 5 warning signs investors should review. Among 1,196 Biotechnology companies, X4 Pharmaceuticals ranks worse than 94.57% on this metric.
Shares Outstanding (EOP) are shares that have been authorized, issued, and purchased by investors and are held by them.
3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. A positive ratio may indicate share buybacks over the period, while a zero or negative ratio may reflect no repurchases or potential share issuance. X4 Pharmaceuticals's current 3-Year Share Buyback Ratio was -181.90%.
The historical rank and industry rank for X4 Pharmaceuticals's 3-Year Share Buyback Ratio or its related term are showing as below:
XFOR'
s 3-Year Share Buyback Ratio Range Over the Past 10 Years
Min: -181.9 Med: -101.95 Max: -10.5
Current: -181.9
During the past 11 years, X4 Pharmaceuticals's highest 3-Year Share Buyback Ratio was -10.50%. The lowest was -181.90%. And the median was -101.95%.
XFOR's 3-Year Share Buyback Ratio is ranked worse than 94.57% of 1196
companies
in the Biotechnology industry
Industry Median: -11.8
vs XFOR: -181.90
X4 Pharmaceuticals (NAS:XFOR) 3-Year Share Buyback Ratio Explanation
A negative number means the company might be issuing new shares. A positive number indicates that the company is buying back shares.
Be Aware
Investors usually like share buybacks. But as pointed by Warren Buffett, only if a company buys back shares at the prices below the stock's intrinsic value, it rewards remaining shareholders. If a company buys its overvalued stocks back, it destroys shareholder value.
X4 Pharmaceuticals 3-Year Share Buyback Ratio Related Terms
XFOR vs CMPX, LRMR, PROK: 3-Year Share Buyback Ratio Comparison
For the Biotechnology subindustry, X4 Pharmaceuticals's 3-Year Share Buyback Ratio, along with its competitors' market caps and 3-Year Share Buyback Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
X4 Pharmaceuticals 3-Year Share Buyback Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, X4 Pharmaceuticals's 3-Year Share Buyback Ratio distribution charts can be found below:
* The bar in red indicates where X4 Pharmaceuticals's 3-Year Share Buyback Ratio falls into.
X4 Pharmaceuticals 3-Year Share Buyback Ratio Calculation
This is the annualized percentage change in shares outstanding from three years ago to the current year. The annualized percentage change is calculated with expontential compound based on the latest four years of annual data on Shares Outstanding (EOP).
Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average dividends per share growth rate.
What does a 3-Year Share Buyback Ratio of -181.90 mean?
X4 Pharmaceuticals (XFOR) has a 3-Year Share Buyback Ratio of -181.90 as of Mar. 2026. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for X4 Pharmaceuticals and its competitors. According to the industry distribution chart, X4 Pharmaceuticals ranks #1131 out of 1196 companies in the Biotechnology industry, placing it in the top 94.6%.
Is X4 Pharmaceuticals' 3-Year Share Buyback Ratio too high?
X4 Pharmaceuticals' current 3-Year Share Buyback Ratio is -181.90. Based on the distribution chart, X4 Pharmaceuticals ranks #1131 out of 1196 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, X4 Pharmaceuticals has a GF Score™ of 24/100, reflecting its overall financial health beyond just this single metric.
How does X4 Pharmaceuticals' 3-Year Share Buyback Ratio compare to CMPX and LRMR?
According to the Biotechnology industry distribution chart, X4 Pharmaceuticals ranks #1131 out of 1196 companies for 3-Year Share Buyback Ratio. This places X4 Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year Share Buyback Ratio for a Biotechnology company?
A good 3-Year Share Buyback Ratio depends on the Biotechnology industry context. However, 3-Year Share Buyback Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year Share Buyback Ratio mean?
A high 3-Year Share Buyback Ratio can signal that a stock is expensive relative to its fundamentals. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for X4 Pharmaceuticals and its competitors. X4 Pharmaceuticals's current 3-Year Share Buyback Ratio is -181.90. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is X4 Pharmaceuticals stock overvalued right now?
X4 Pharmaceuticals (XFOR) has a current 3-Year Share Buyback Ratio of -181.90. The current 3-Year Share Buyback Ratio is -181.90. X4 Pharmaceuticals' overall GF Score™ is 24/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year Share Buyback Ratio calculated?
3-Year Share Buyback Ratio is calculated from a company's financial statements. For X4 Pharmaceuticals (XFOR), the current 3-Year Share Buyback Ratio is -181.90 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
X4 Pharmaceuticals Inc is a biopharmaceutical company developing and commercializing novel therapeutics for the treatment of rare hematology diseases. The Company's clinical candidate is mavorixafor, a small molecule antagonist of the chemokine receptor CXCR4 that is being developed as an oral, once-daily therapy. It can increase the mobilization of mature, functional white blood cells from the bone marrow into the bloodstream. It also has two pre-clinical candidates X4P-003 and X4P-002 which are CXCR4 antagonists with different properties.
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