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Apogee TherapeuticsAPGE +0.10%12 EV-to-EBITDA is -29.96 as of Jul. 23, 2026. GuruFocus rates APGE with a GF Score™ of 12/100. The stock has 3 warning signs investors should review. Among 400 Biotechnology companies, Apogee Therapeutics ranks worse than 249999.75% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Apogee Therapeutics's enterprise value is $9,098.42 Mil.
Apogee Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-303.65 Mil. Therefore, Apogee Therapeutics's EV-to-EBITDA for today is -29.96.
The historical rank and industry rank for Apogee Therapeutics's EV-to-EBITDA or its related term are showing as below:
APGE'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -29.99 Med: 0 Max: 0
Current: -29.96
APGE's EV-to-EBITDA is ranked worse than 100% of 400
companies
in the Biotechnology industry
Industry Median: 12.15
vs APGE: -29.96
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Apogee Therapeutics's PE Ratio (TTM) for today is calculated as:
Apogee Therapeutics's share price for today is $134.215.
Apogee Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-4.330.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Apogee Therapeutics's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Apogee Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Apogee Therapeutics EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Apogee Therapeutics's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Apogee Therapeutics's EV-to-EBITDA falls into.
Apogee Therapeutics's current Enterprise Value is $9,098.42 Mil.
Apogee Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-303.65 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Apogee Therapeutics (APGE) has a EV-to-EBITDA of -29.96 as of Jul. 23, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Apogee Therapeutics. According to the industry distribution chart, Apogee Therapeutics ranks #999999 out of 400 companies in the Biotechnology industry.
Is Apogee Therapeutics' EV-to-EBITDA too high?
Apogee Therapeutics' current EV-to-EBITDA is -29.96. Based on the distribution chart, Apogee Therapeutics ranks #999999 out of 400 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Apogee Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Apogee Therapeutics' EV-to-EBITDA compare to NUVL and CORT?
According to the Biotechnology industry distribution chart, Apogee Therapeutics ranks #999999 out of 400 companies for EV-to-EBITDA. This places Apogee Therapeutics in the lower half of its industry. The industry median EV-to-EBITDA is 12.15. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.15, based on 400 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Apogee Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 12.15 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Apogee Therapeutics's current EV-to-EBITDA is -29.96. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Apogee Therapeutics stock overvalued right now?
Apogee Therapeutics (APGE) has a current EV-to-EBITDA of -29.96. The current EV-to-EBITDA is -29.96. Apogee Therapeutics' overall GF Score™ is 12/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Apogee Therapeutics (APGE), the current EV-to-EBITDA is -29.96 as of Jul. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Apogee Therapeutics Inc is a clinical-stage biotechnology company engaged in advancing optimized, novel biologics with the potential for differentiated efficacy and dosing in the inflammatory and immunology (I&I) markets, including for the treatment of atopic dermatitis (AD), asthma, eosinophilic esophagitis (EoE), chronic obstructive pulmonary disease (COPD), and other I&I indications. . Its antibody programs are designed to overcome the limitations of existing therapies by targeting well-established mechanisms of action and incorporating antibody engineering to optimize half-life and other properties.
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