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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Starpharma Holdings's enterprise value is A$289.25 Mil.
Starpharma Holdings's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was A$-3.95 Mil. Therefore, Starpharma Holdings's EV-to-EBITDA for today is -73.17.
The historical rank and industry rank for Starpharma Holdings's EV-to-EBITDA or its related term are showing as below:
ASX:SPL'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -73.17 Med: -15.26 Max: -0.61
Current: -73.17
During the past 13 years, the highest EV-to-EBITDA of Starpharma Holdings was -0.61. The lowest was -73.17. And the median was -15.26.
ASX:SPL's EV-to-EBITDA is ranked worse than 100% of 398
companies
in the Biotechnology industry
Industry Median: 12.205
vs ASX:SPL: -73.17
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Starpharma Holdings's PE Ratio (TTM) for today is calculated as:
Starpharma Holdings's share price for today is A$0.71.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Starpharma Holdings's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was A$-0.008.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Starpharma Holdings's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ASX:SPL vs VRTX, REGN, ALNY: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Starpharma Holdings's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Starpharma Holdings EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Starpharma Holdings's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Starpharma Holdings's EV-to-EBITDA falls into.
Starpharma Holdings's current Enterprise Value is A$289.25 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Starpharma Holdings's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was A$-3.95 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Starpharma Holdings (ASX:SPL) has a EV-to-EBITDA of -73.17 as of Jul. 20, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Starpharma Holdings. According to the industry distribution chart, Starpharma Holdings ranks #999999 out of 398 companies in the Biotechnology industry.
Is Starpharma Holdings' EV-to-EBITDA too high?
Starpharma Holdings' current EV-to-EBITDA is -73.17. Based on the distribution chart, Starpharma Holdings ranks #999999 out of 398 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Starpharma Holdings has a GF Score™ of 48/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Starpharma Holdings' EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Starpharma Holdings ranks #999999 out of 398 companies for EV-to-EBITDA. This places Starpharma Holdings in the lower half of its industry. The industry median EV-to-EBITDA is 12.21. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.21, based on 398 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Starpharma Holdings. For the Biotechnology industry, the median EV-to-EBITDA is 12.21 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Starpharma Holdings's current EV-to-EBITDA is -73.17. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Starpharma Holdings stock overvalued right now?
Based on GuruFocus' analysis, Starpharma Holdings (ASX:SPL) is currently considered Significantly Overvalued. The stock's GF Value™ is A$0.48, compared to a current price of A$0.71 — trading 47.9% above its estimated fair value. The current EV-to-EBITDA is -73.17. Starpharma Holdings' overall GF Score™ is 48/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Starpharma Holdings (ASX:SPL), the current EV-to-EBITDA is -73.17 as of Jul. 20, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Starpharma Holdings (ASX:SPL) Overvalued in 2026?
Based on GuruFocus' analysis, Starpharma Holdings stock appears to be overvalued.
The current stock price of A$0.71 is trading 47.9% above its estimated GF Value™ of A$0.48.
GuruFocus considers Starpharma Holdings to be Significantly Overvalued.
Key valuation signals for ASX:SPL:
EV-to-EBITDA: -73.17
GF Value™: A$0.48 vs. price of A$0.71 (47.9% above fair value)
No single metric tells the full story. See the ASX:SPL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Starpharma Holdings Ltd is an Australia-based company engaged in the research, development, and commercialization of dendrimer products for pharmaceutical, life science, and other applications. It focuses on the development of VivaGel for the management and prevention of bacterial vaginosis and as a condom coating, and VIRALEZE, an antiviral nasal spray.
48GF Score
Get the complete analysis for ASX:SPL
EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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