CDIO (Cardio Diagnostics Holdings) EV-to-EBITDA: 0.31 (As of Jul. 30, 2026)

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CDIO Cardio Diagnostics Holdings Inc CDIO
49 GF Score
Price $1.56
GF Value $2.77
Valuation Possible Value Trap
! 3 Warning Signs
View Full Analysis

What is Cardio Diagnostics Holdings EV-to-EBITDA?

Cardio Diagnostics Holdings CDIO -0.49% 49 EV-to-EBITDA is 0.31 as of Jul. 30, 2026. GuruFocus rates CDIO with a GF Score™ of 49/100 and a GF Value™ of $2.77 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 410 Biotechnology companies, Cardio Diagnostics Holdings ranks better than 89.27% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Cardio Diagnostics Holdings's enterprise value is $-1.93 Mil. Cardio Diagnostics Holdings's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-6.27 Mil. Therefore, Cardio Diagnostics Holdings's EV-to-EBITDA for today is 0.31.

The historical rank and industry rank for Cardio Diagnostics Holdings's EV-to-EBITDA or its related term are showing as below:

CDIO' s EV-to-EBITDA Range Over the Past 10 Years
Min: -85.07   Med: -1.21   Max: 0.51
Current: 0.31

During the past 6 years, the highest EV-to-EBITDA of Cardio Diagnostics Holdings was 0.51. The lowest was -85.07. And the median was -1.21.

CDIO's EV-to-EBITDA is ranked better than
89.27% of 410 companies
in the Biotechnology industry
Industry Median: 11.46 vs CDIO: 0.31

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-07-30), Cardio Diagnostics Holdings's stock price is $1.56. Cardio Diagnostics Holdings's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-3.380. Therefore, Cardio Diagnostics Holdings's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Cardio Diagnostics Holdings  (NAS:CDIO) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Cardio Diagnostics Holdings's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=1.56/-3.380
=At Loss

Cardio Diagnostics Holdings's share price for today is $1.56.
Cardio Diagnostics Holdings's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-3.380.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Cardio Diagnostics Holdings EV-to-EBITDA Related Terms


Cardio Diagnostics Holdings EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Cardio Diagnostics Holdings's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cardio Diagnostics Holdings EV-to-EBITDA Chart

Cardio Diagnostics Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial 0.00 -1.47 -33.43 -4.36 -0.09

Cardio Diagnostics Holdings Quarterly Data
Mar21 Jun21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.52 0.18 -0.20 -0.09 0.12

CDIO vs ERNA, LABT, JAGX: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Cardio Diagnostics Holdings's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cardio Diagnostics Holdings EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cardio Diagnostics Holdings's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Cardio Diagnostics Holdings's EV-to-EBITDA falls into.


CDIO
49GF Score
Cardio Diagnostics Holdings Inc CDIO
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Cardio Diagnostics Holdings EV-to-EBITDA Calculation

Cardio Diagnostics Holdings's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=-1.929/-6.27
=0.31

Cardio Diagnostics Holdings's current Enterprise Value is $-1.93 Mil.
Cardio Diagnostics Holdings's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-6.27 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of 0.31 mean?
Cardio Diagnostics Holdings (CDIO) has a EV-to-EBITDA of 0.31 as of Jul. 30, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Cardio Diagnostics Holdings. According to the industry distribution chart, Cardio Diagnostics Holdings ranks #44 out of 410 companies in the Biotechnology industry, placing it in the top 10.7%.
Is Cardio Diagnostics Holdings' EV-to-EBITDA too high?
Cardio Diagnostics Holdings' current EV-to-EBITDA is 0.31. The Biotechnology industry median EV-to-EBITDA is 11.46. Cardio Diagnostics Holdings' value of 0.31 is 97.3% below this industry median. Based on the distribution chart, Cardio Diagnostics Holdings ranks #44 out of 410 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Cardio Diagnostics Holdings has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Cardio Diagnostics Holdings' EV-to-EBITDA compare to ERNA and LABT?
According to the Biotechnology industry distribution chart, Cardio Diagnostics Holdings ranks #44 out of 410 companies for EV-to-EBITDA. This places Cardio Diagnostics Holdings in the top 11% of its industry — outperforming the majority of peers. The industry median EV-to-EBITDA is 11.46. Cardio Diagnostics Holdings' value of 0.31 is 97.3% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 11.46, based on 410 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Cardio Diagnostics Holdings's current EV-to-EBITDA of 0.31 is 97.3% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Cardio Diagnostics Holdings. For the Biotechnology industry, the median EV-to-EBITDA is 11.46 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Cardio Diagnostics Holdings's current EV-to-EBITDA is 0.31. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cardio Diagnostics Holdings stock overvalued right now?
Based on GuruFocus' analysis, Cardio Diagnostics Holdings (CDIO) is currently considered Possible Value Trap. The stock's GF Value™ is $2.77, compared to a current price of $1.56 — trading 43.7% below its estimated fair value. The current EV-to-EBITDA is 0.31 and 97.3% below the Biotechnology industry median of 11.46. Cardio Diagnostics Holdings' overall GF Score™ is 49/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Cardio Diagnostics Holdings (CDIO), the current EV-to-EBITDA is 0.31 as of Jul. 30, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cardio Diagnostics Holdings (CDIO) Overvalued in 2026?

Based on GuruFocus' analysis, Cardio Diagnostics Holdings stock appears to be undervalued. The current stock price of $1.56 is trading 43.7% below its estimated GF Value™ of $2.77. GuruFocus considers Cardio Diagnostics Holdings to be Possible Value Trap.

Key valuation signals for CDIO:

  • EV-to-EBITDA: 0.31
  • GF Value™: $2.77 vs. price of $1.56 (43.7% below fair value)
  • GF Score™: 49/100 with 3 warning signs
  • Industry Position: 97.3% below the Biotechnology median (#44 of 410)

No single metric tells the full story. See the CDIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cardio Diagnostics Holdings Business Description

Address 311 West Superior Street, Suite 444, Chicago, IL, USA, 60654
Cardio Diagnostics Holdings Inc is a medical technology company focused on developing and commercializing epigenetics-based clinical tests for cardiovascular diseases and associated comorbidities by leveraging its Artificial Intelligence (AI)-driven Multi-Omics Engine. The company has developed two clinical products: Epi+Gen CHD and PrecisionCHD, epigenetics-based clinical blood tests capable of assessing risk for a coronary heart disease (CHD) event, including heart attacks. Additionally, its portfolio includes HeartRisk, a cardiovascular disease risk intelligence platform, and CardioInnovate360, a research-use-only solution launched to support the discovery, development, and validation of novel biopharmaceuticals for the assessment and management of cardiovascular diseases.
49GF Score

Get the complete analysis for CDIO

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.56
Price
$2.77
GF Value