CDIO (Cardio Diagnostics Holdings) ROA %: -82.56% (As of Mar. 2026)

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CDIO Cardio Diagnostics Holdings Inc CDIO
49 GF Score
Price $1.57
GF Value $2.77
Valuation Possible Value Trap
! 3 Warning Signs
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What is Cardio Diagnostics Holdings ROA %?

Cardio Diagnostics Holdings CDIO +0.15% 49 ROA % is -82.56% as of Mar. 2026. GuruFocus rates CDIO with a GF Score™ of 49/100 and a GF Value™ of $2.77 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 1,415 Biotechnology companies, Cardio Diagnostics Holdings ranks worse than 73.57% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Cardio Diagnostics Holdings's annualized Net Income for the quarter that ended in Mar. 2026 was $-7.15 Mil. Cardio Diagnostics Holdings's average Total Assets over the quarter that ended in Mar. 2026 was $8.66 Mil. Therefore, Cardio Diagnostics Holdings's annualized ROA % for the quarter that ended in Mar. 2026 was -82.56%.

The historical rank and industry rank for Cardio Diagnostics Holdings's ROA % or its related term are showing as below:

CDIO' s ROA % Range Over the Past 10 Years
Min: -156.42   Med: -119.01   Max: -68.16
Current: -68.16

During the past 6 years, Cardio Diagnostics Holdings's highest ROA % was -68.16%. The lowest was -156.42%. And the median was -119.01%.

CDIO's ROA % is ranked worse than
73.57% of 1415 companies
in the Biotechnology industry
Industry Median: -32.84 vs CDIO: -68.16

Cardio Diagnostics Holdings  (NAS:CDIO) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-7.152/8.6625
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-7.152 / 0.012)*(0.012 / 8.6625)
=Net Margin %*Asset Turnover
=-59600 %*0.0014
=-82.56 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Cardio Diagnostics Holdings ROA % Related Terms


Cardio Diagnostics Holdings ROA % Historical Data

* Premium members only.

The historical data trend for Cardio Diagnostics Holdings's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cardio Diagnostics Holdings ROA % Chart

Cardio Diagnostics Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial -80.10 -126.81 -156.42 -111.20 -70.70

Cardio Diagnostics Holdings Quarterly Data
Mar21 Jun21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -57.13 -59.37 -71.51 -70.79 -82.56

CDIO vs ERNA, LABT, JAGX: ROA % Comparison

For the Biotechnology subindustry, Cardio Diagnostics Holdings's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cardio Diagnostics Holdings ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cardio Diagnostics Holdings's ROA % distribution charts can be found below:

* The bar in red indicates where Cardio Diagnostics Holdings's ROA % falls into.


CDIO
49GF Score
Cardio Diagnostics Holdings Inc CDIO
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Cardio Diagnostics Holdings ROA % Calculation

Cardio Diagnostics Holdings's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-6.498/( (10.615+7.766)/ 2 )
=-6.498/9.1905
=-70.70 %

Cardio Diagnostics Holdings's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-7.152/( (7.766+9.559)/ 2 )
=-7.152/8.6625
=-82.56 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -82.56% mean?
Cardio Diagnostics Holdings (CDIO) has a ROA % of -82.56% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Cardio Diagnostics Holdings and its competitors. According to the industry distribution chart, Cardio Diagnostics Holdings ranks #1041 out of 1415 companies in the Biotechnology industry, placing it in the top 73.6%.
Is Cardio Diagnostics Holdings' ROA % too high?
Cardio Diagnostics Holdings' current ROA % is -82.56%. Based on the distribution chart, Cardio Diagnostics Holdings ranks #1041 out of 1415 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Cardio Diagnostics Holdings has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Cardio Diagnostics Holdings' ROA % compare to ERNA and LABT?
According to the Biotechnology industry distribution chart, Cardio Diagnostics Holdings ranks #1041 out of 1415 companies for ROA %. This places Cardio Diagnostics Holdings in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Cardio Diagnostics Holdings and its competitors. Cardio Diagnostics Holdings's current ROA % is -82.56%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cardio Diagnostics Holdings stock overvalued right now?
Based on GuruFocus' analysis, Cardio Diagnostics Holdings (CDIO) is currently considered Possible Value Trap. The stock's GF Value™ is $2.77, compared to a current price of $1.57 — trading 43.3% below its estimated fair value. The current ROA % is -82.56%. Cardio Diagnostics Holdings' overall GF Score™ is 49/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Cardio Diagnostics Holdings (CDIO), the current ROA % is -82.56% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cardio Diagnostics Holdings (CDIO) Overvalued in 2026?

Based on GuruFocus' analysis, Cardio Diagnostics Holdings stock appears to be undervalued. The current stock price of $1.57 is trading 43.3% below its estimated GF Value™ of $2.77. GuruFocus considers Cardio Diagnostics Holdings to be Possible Value Trap.

Key valuation signals for CDIO:

  • ROA %: -82.56%
  • GF Value™: $2.77 vs. price of $1.57 (43.3% below fair value)
  • GF Score™: 49/100 with 3 warning signs

No single metric tells the full story. See the CDIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cardio Diagnostics Holdings Business Description

Address 311 West Superior Street, Suite 444, Chicago, IL, USA, 60654
Cardio Diagnostics Holdings Inc is a medical technology company focused on developing and commercializing epigenetics-based clinical tests for cardiovascular diseases and associated comorbidities by leveraging its Artificial Intelligence (AI)-driven Multi-Omics Engine. The company has developed two clinical products: Epi+Gen CHD and PrecisionCHD, epigenetics-based clinical blood tests capable of assessing risk for a coronary heart disease (CHD) event, including heart attacks. Additionally, its portfolio includes HeartRisk, a cardiovascular disease risk intelligence platform, and CardioInnovate360, a research-use-only solution launched to support the discovery, development, and validation of novel biopharmaceuticals for the assessment and management of cardiovascular diseases.
49GF Score

Get the complete analysis for CDIO

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.57
Price
$2.77
GF Value