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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Guardant HealthGH +0.57%65 EV-to-EBITDA is -51.34 as of Aug. 05, 2026. GuruFocus rates GH with a GF Score™ of 65/100 and a GF Value™ of $65.16 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 119 Medical Diagnostics & Research companies, Guardant Health ranks worse than 840335.29% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Guardant Health's enterprise value is $22,087 Mil.
Guardant Health's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $-430 Mil. Therefore, Guardant Health's EV-to-EBITDA for today is -51.34.
The historical rank and industry rank for Guardant Health's EV-to-EBITDA or its related term are showing as below:
GH'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -138.6 Med: -27.53 Max: -4.42
Current: -51.34
During the past 10 years, the highest EV-to-EBITDA of Guardant Health was -4.42. The lowest was -138.60. And the median was -27.53.
GH's EV-to-EBITDA is ranked worse than 100% of 119
companies
in the Medical Diagnostics & Research industry
Industry Median: 15.33
vs GH: -51.34
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Guardant Health's PE Ratio (TTM) for today is calculated as:
Guardant Health's share price for today is $159.84.
Guardant Health's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-3.490.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Guardant Health's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Diagnostics & Research subindustry, Guardant Health's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Guardant Health EV-to-EBITDA vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Guardant Health's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Guardant Health's EV-to-EBITDA falls into.
Guardant Health's current Enterprise Value is $22,087 Mil.
Guardant Health's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-430 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Guardant Health (GH) has a EV-to-EBITDA of -51.34 as of Aug. 05, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Guardant Health. According to the industry distribution chart, Guardant Health ranks #999999 out of 119 companies in the Medical Diagnostics & Research industry.
Is Guardant Health's EV-to-EBITDA too high?
Guardant Health's current EV-to-EBITDA is -51.34. Based on the distribution chart, Guardant Health ranks #999999 out of 119 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Guardant Health has a GF Score™ of 65/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Guardant Health's EV-to-EBITDA compare to MEDP and LH?
According to the Medical Diagnostics & Research industry distribution chart, Guardant Health ranks #999999 out of 119 companies for EV-to-EBITDA. This places Guardant Health in the lower half of its industry. The industry median EV-to-EBITDA is 15.33. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Medical Diagnostics & Research company?
The median EV-to-EBITDA among Medical Diagnostics & Research companies is 15.33, based on 119 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Guardant Health. For the Medical Diagnostics & Research industry, the median EV-to-EBITDA is 15.33 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Guardant Health's current EV-to-EBITDA is -51.34. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Guardant Health stock overvalued right now?
Based on GuruFocus' analysis, Guardant Health (GH) is currently considered Significantly Overvalued. The stock's GF Value™ is $65.16, compared to a current price of $159.84 — trading 145.3% above its estimated fair value. The current EV-to-EBITDA is -51.34. Guardant Health's overall GF Score™ is 65/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Guardant Health (GH), the current EV-to-EBITDA is -51.34 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Guardant Health (GH) Overvalued in 2026?
Based on GuruFocus' analysis, Guardant Health stock appears to be overvalued.
The current stock price of $159.84 is trading 145.3% above its estimated GF Value™ of $65.16.
GuruFocus considers Guardant Health to be Significantly Overvalued.
Key valuation signals for GH:
EV-to-EBITDA: -51.34
GF Value™: $65.16 vs. price of $159.84 (145.3% above fair value)
No single metric tells the full story. See the GH stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Guardant Health, based in Redwood City, California, is a leader in liquid-based cancer tests for clinical and research use. The company's main franchises are Guardant360 for genomic profiling of tumors, Reveal for molecular residual disease testing, and Shield for colorectal cancer screening. Additionally, Guardant offers research development services such as regulatory approval consultancy and clinical trial referrals.
65GF Score
Get the complete analysis for GH
EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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