Oculis Holding AG (OISE:OCS) EV-to-EBITDA: -3.58 (As of Aug. 01, 2026)

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OISE:OCS Oculis Holding AG OISE:OCS
26 GF Score
Price kr1,370.00
! 1 Warning Sign
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What is Oculis Holding AG EV-to-EBITDA?

Oculis Holding AG OISE:OCS +1.48% 26 EV-to-EBITDA is -3.58 as of Aug. 01, 2026. GuruFocus rates OISE:OCS with a GF Score™ of 26/100. The stock has 1 warning sign investors should review. Among 411 Biotechnology companies, Oculis Holding AG ranks worse than 243308.76% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Oculis Holding AG's enterprise value is kr51,728.64 Mil. Oculis Holding AG's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was kr-14,434.65 Mil. Therefore, Oculis Holding AG's EV-to-EBITDA for today is -3.58.

The historical rank and industry rank for Oculis Holding AG's EV-to-EBITDA or its related term are showing as below:

OISE:OCS' s EV-to-EBITDA Range Over the Past 10 Years
Min: -3.5   Med: 0   Max: 0
Current: -3.5

OISE:OCS's EV-to-EBITDA is ranked worse than
100% of 411 companies
in the Biotechnology industry
Industry Median: 12.05 vs OISE:OCS: -3.50

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-08-01), Oculis Holding AG's stock price is kr1370.00. Oculis Holding AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was kr-267.174. Therefore, Oculis Holding AG's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Oculis Holding AG  (OISE:OCS) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Oculis Holding AG's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=1370.00/-267.174
=At Loss

Oculis Holding AG's share price for today is kr1370.00.
Oculis Holding AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was kr-267.174.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Oculis Holding AG EV-to-EBITDA Related Terms


Oculis Holding AG EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Oculis Holding AG's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oculis Holding AG EV-to-EBITDA Chart

Oculis Holding AG Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial 0.00 0.00 -3.04 -6.65 -7.28

Oculis Holding AG Quarterly Data
Dec20 Sep21 Dec21 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -6.80 -6.65 -6.14 -7.28 -11.32

OISE:OCS vs RIGL, GYRE, SGP: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Oculis Holding AG's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oculis Holding AG EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oculis Holding AG's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Oculis Holding AG's EV-to-EBITDA falls into.


OISE:OCS
26GF Score
Oculis Holding AG OISE:OCS
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
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Oculis Holding AG EV-to-EBITDA Calculation

Oculis Holding AG's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=51728.644/-14434.647
=-3.58

Oculis Holding AG's current Enterprise Value is kr51,728.64 Mil.
Oculis Holding AG's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was kr-14,434.65 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -3.58 mean?
Oculis Holding AG (OISE:OCS) has a EV-to-EBITDA of -3.58 as of Aug. 01, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Oculis Holding AG. According to the industry distribution chart, Oculis Holding AG ranks #999999 out of 411 companies in the Biotechnology industry.
Is Oculis Holding AG's EV-to-EBITDA too high?
Oculis Holding AG's current EV-to-EBITDA is -3.58. Based on the distribution chart, Oculis Holding AG ranks #999999 out of 411 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Oculis Holding AG has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.
How does Oculis Holding AG's EV-to-EBITDA compare to RIGL and GYRE?
According to the Biotechnology industry distribution chart, Oculis Holding AG ranks #999999 out of 411 companies for EV-to-EBITDA. This places Oculis Holding AG in the lower half of its industry. The industry median EV-to-EBITDA is 12.05. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.05, based on 411 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Oculis Holding AG. For the Biotechnology industry, the median EV-to-EBITDA is 12.05 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Oculis Holding AG's current EV-to-EBITDA is -3.58. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oculis Holding AG stock overvalued right now?
Oculis Holding AG (OISE:OCS) has a current EV-to-EBITDA of -3.58. The current EV-to-EBITDA is -3.58. Oculis Holding AG's overall GF Score™ is 26/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Oculis Holding AG (OISE:OCS), the current EV-to-EBITDA is -3.58 as of Aug. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Oculis Holding AG Business Description

Other Exchanges OCS:USACR5:Germany
Address Bahnhofstrasse 20, Zug, CHE, CH-6300
Oculis Holding AG is a biopharmaceutical company purposefully driven to save sight and improve eye care. It includes OCS-01, a topical retinal candidate for diabetic macular edema (DME); OCS-02, a topical biologic candidate for dry eye disease (DED); and OCS-05, a disease modifying candidate for acute optic neuritis (AON) and other neuro-ophtha disorders such as glaucoma, diabetic retinopathy, geographic atrophy, and neurotrophic keratitis. The Company has locations in five countries: Switzerland, Iceland, France, U.S. and Hong Kong.
26GF Score

Get the complete analysis for OISE:OCS

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

kr1,370.00
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