Japan Tissue Engineering Co (TSE:7774) EV-to-EBITDA: -363.38 (As of Aug. 29, 2026)

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TSE:7774 Japan Tissue Engineering Co Ltd TSE:7774
56 GF Score
Price 円874.00
GF Value 円505.36
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is Japan Tissue Engineering Co EV-to-EBITDA?

Japan Tissue Engineering Co TSE:7774 +3.07% 56 EV-to-EBITDA is -363.38 as of Aug. 29, 2026. GuruFocus rates TSE:7774 with a GF Score™ of 56/100 and a GF Value™ of 円505.36 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 414 Biotechnology companies, Japan Tissue Engineering Co ranks worse than 241545.65% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Japan Tissue Engineering Co's enterprise value is 円32,146 Mil. Japan Tissue Engineering Co's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was 円-88 Mil. Therefore, Japan Tissue Engineering Co's EV-to-EBITDA for today is -363.38.

The historical rank and industry rank for Japan Tissue Engineering Co's EV-to-EBITDA or its related term are showing as below:

TSE:7774' s EV-to-EBITDA Range Over the Past 10 Years
Min: -392.9   Med: -51.32   Max: 638.56
Current: -363.38

During the past 13 years, the highest EV-to-EBITDA of Japan Tissue Engineering Co was 638.56. The lowest was -392.90. And the median was -51.32.

TSE:7774's EV-to-EBITDA is ranked worse than
100% of 414 companies
in the Biotechnology industry
Industry Median: 13.55 vs TSE:7774: -363.38

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-08-29), Japan Tissue Engineering Co's stock price is 円874.00. Japan Tissue Engineering Co's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was 円-10.830. Therefore, Japan Tissue Engineering Co's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Japan Tissue Engineering Co  (TSE:7774) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Japan Tissue Engineering Co's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=874.00/-10.830
=At Loss

Japan Tissue Engineering Co's share price for today is 円874.00.
Japan Tissue Engineering Co's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-10.830.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Japan Tissue Engineering Co EV-to-EBITDA Related Terms


Japan Tissue Engineering Co EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Japan Tissue Engineering Co's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Japan Tissue Engineering Co EV-to-EBITDA Chart

Japan Tissue Engineering Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
EV-to-EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only -42.61 -28.53 82.21 -183.79 -53.44

Japan Tissue Engineering Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -112.85 -56.07 -38.93 -53.44 0.00

TSE:7774 vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Japan Tissue Engineering Co's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Japan Tissue Engineering Co EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Japan Tissue Engineering Co's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Japan Tissue Engineering Co's EV-to-EBITDA falls into.


TSE:7774
56GF Score
Japan Tissue Engineering Co Ltd TSE:7774
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Japan Tissue Engineering Co EV-to-EBITDA Calculation

Japan Tissue Engineering Co's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=32145.830/-88.463
=-363.38

Japan Tissue Engineering Co's current Enterprise Value is 円32,146 Mil.
Japan Tissue Engineering Co's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-88 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -363.38 mean?
Japan Tissue Engineering Co (TSE:7774) has a EV-to-EBITDA of -363.38 as of Aug. 29, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Japan Tissue Engineering Co. According to the industry distribution chart, Japan Tissue Engineering Co ranks #999999 out of 414 companies in the Biotechnology industry.
Is Japan Tissue Engineering Co's EV-to-EBITDA too high?
Japan Tissue Engineering Co's current EV-to-EBITDA is -363.38. Based on the distribution chart, Japan Tissue Engineering Co ranks #999999 out of 414 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Japan Tissue Engineering Co has a GF Score™ of 56/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Japan Tissue Engineering Co's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Japan Tissue Engineering Co ranks #999999 out of 414 companies for EV-to-EBITDA. This places Japan Tissue Engineering Co in the lower half of its industry. The industry median EV-to-EBITDA is 13.55. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.55, based on 414 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Japan Tissue Engineering Co. For the Biotechnology industry, the median EV-to-EBITDA is 13.55 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Japan Tissue Engineering Co's current EV-to-EBITDA is -363.38. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Japan Tissue Engineering Co stock overvalued right now?
Based on GuruFocus' analysis, Japan Tissue Engineering Co (TSE:7774) is currently considered Significantly Overvalued. The stock's GF Value™ is 円505.36, compared to a current price of 円874.00 — trading 72.9% above its estimated fair value. The current EV-to-EBITDA is -363.38. Japan Tissue Engineering Co's overall GF Score™ is 56/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Japan Tissue Engineering Co (TSE:7774), the current EV-to-EBITDA is -363.38 as of Aug. 29, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Japan Tissue Engineering Co (TSE:7774) Overvalued in 2026?

Based on GuruFocus' analysis, Japan Tissue Engineering Co stock appears to be overvalued. The current stock price of 円874.00 is trading 72.9% above its estimated GF Value™ of 円505.36. GuruFocus considers Japan Tissue Engineering Co to be Significantly Overvalued.

Key valuation signals for TSE:7774:

  • EV-to-EBITDA: -363.38
  • GF Value™: 円505.36 vs. price of 円874.00 (72.9% above fair value)
  • GF Score™: 56/100 with 4 warning signs

No single metric tells the full story. See the TSE:7774 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Japan Tissue Engineering Co Business Description

Address 6-209-1 Miyakitadori, Gamagori, Aichi, JPN, 443-0022
Japan Tissue Engineering Co Ltd is a bio-venture enterprise. It is engaged in the development, manufacture, and sale of tissue-engineered medical products and related products. It operates through the Regenerative Medicine, and Research and Development support business segments. The main business goal is to use autologous culturing techniques to develop tissue-engineered medical products and then to manufacture and sell these same tissue-engineered products to medical institutions for medical treatment. The company's tissue-engineered medical products are used in autologous transplant cases, where living cells are taken from the actual patient himself, cultured and then transplanted back to that same patient.
56GF Score

Get the complete analysis for TSE:7774

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円874.00
Price
円505.36
GF Value