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Zentalis PharmaceuticalsZNTL +4.81%30 EV-to-EBITDA is -0.82 as of Aug. 17, 2026. GuruFocus rates ZNTL with a GF Score™ of 30/100. The stock has 3 warning signs investors should review. Among 401 Biotechnology companies, Zentalis Pharmaceuticals ranks worse than 249376.31% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Zentalis Pharmaceuticals's enterprise value is $124.50 Mil.
Zentalis Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $-152.75 Mil. Therefore, Zentalis Pharmaceuticals's EV-to-EBITDA for today is -0.82.
The historical rank and industry rank for Zentalis Pharmaceuticals's EV-to-EBITDA or its related term are showing as below:
ZNTL'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -2.95 Med: 0.64 Max: 1.11
Current: -0.82
During the past 8 years, the highest EV-to-EBITDA of Zentalis Pharmaceuticals was 1.11. The lowest was -2.95. And the median was 0.64.
ZNTL's EV-to-EBITDA is ranked worse than 100% of 401
companies
in the Biotechnology industry
Industry Median: 13.8
vs ZNTL: -0.82
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Zentalis Pharmaceuticals's PE Ratio (TTM) for today is calculated as:
Zentalis Pharmaceuticals's share price for today is $3.705.
Zentalis Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.950.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Zentalis Pharmaceuticals's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Zentalis Pharmaceuticals EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Zentalis Pharmaceuticals's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Zentalis Pharmaceuticals's EV-to-EBITDA falls into.
Zentalis Pharmaceuticals's current Enterprise Value is $124.50 Mil.
Zentalis Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-152.75 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Zentalis Pharmaceuticals (ZNTL) has a EV-to-EBITDA of -0.82 as of Aug. 17, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Zentalis Pharmaceuticals. According to the industry distribution chart, Zentalis Pharmaceuticals ranks #999999 out of 401 companies in the Biotechnology industry.
Is Zentalis Pharmaceuticals' EV-to-EBITDA too high?
Zentalis Pharmaceuticals' current EV-to-EBITDA is -0.82. Based on the distribution chart, Zentalis Pharmaceuticals ranks #999999 out of 401 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Zentalis Pharmaceuticals has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Zentalis Pharmaceuticals' EV-to-EBITDA compare to PROK and LYEL?
According to the Biotechnology industry distribution chart, Zentalis Pharmaceuticals ranks #999999 out of 401 companies for EV-to-EBITDA. This places Zentalis Pharmaceuticals in the lower half of its industry. The industry median EV-to-EBITDA is 13.80. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.80, based on 401 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Zentalis Pharmaceuticals. For the Biotechnology industry, the median EV-to-EBITDA is 13.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Zentalis Pharmaceuticals's current EV-to-EBITDA is -0.82. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zentalis Pharmaceuticals stock overvalued right now?
Zentalis Pharmaceuticals (ZNTL) has a current EV-to-EBITDA of -0.82. The current EV-to-EBITDA is -0.82. Zentalis Pharmaceuticals' overall GF Score™ is 30/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Zentalis Pharmaceuticals (ZNTL), the current EV-to-EBITDA is -0.82 as of Aug. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Zentalis Pharmaceuticals Inc is a clinical-stage biopharmaceutical company developing azenosertib (ZN-c3), a potentially first-in-class and best-in-class WEE1 inhibitor for patients with Cyclin E1-positive platinum-resistant ovarian cancer (Cyclin E1+ PROC). The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions.
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