GPCR (Structure Therapeutics) EV-to-OCF: -13.95 (As of Jul. 23, 2026)

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GPCR Structure Therapeutics Inc GPCR
32 GF Score
Price $50.74
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What is Structure Therapeutics EV-to-OCF?

Structure Therapeutics GPCR +0.70% 32 EV-to-OCF is -13.95 as of Jul. 23, 2026. GuruFocus rates GPCR with a GF Score™ of 32/100. Among 1,411 Biotechnology companies, Structure Therapeutics ranks better than 76.12% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Structure Therapeutics's Enterprise Value is $2,157.87 Mil. Structure Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-154.74 Mil. Therefore, Structure Therapeutics's EV-to-OCF for today is -13.95.

The historical rank and industry rank for Structure Therapeutics's EV-to-OCF or its related term are showing as below:

GPCR' s EV-to-OCF Range Over the Past 10 Years
Min: -14.77   Med: 0   Max: -13.73
Current: -13.95

During the past 6 years, the highest EV-to-OCF of Structure Therapeutics was -13.73. The lowest was -14.77. And the median was .

GPCR's EV-to-OCF is ranked better than
76.12% of 1411 companies
in the Biotechnology industry
Industry Median: -3.32 vs GPCR: -13.95

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-07-23), Structure Therapeutics's stock price is $50.74. Structure Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-2.774. Therefore, Structure Therapeutics's PE Ratio (TTM) for today is At Loss.


Structure Therapeutics  (NAS:GPCR) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Structure Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=50.74/-2.774
=At Loss

Structure Therapeutics's share price for today is $50.74.
Structure Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.774.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Structure Therapeutics EV-to-OCF Related Terms


Structure Therapeutics EV-to-OCF Historical Data

* Premium members only.

The historical data trend for Structure Therapeutics's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Structure Therapeutics EV-to-OCF Chart

Structure Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial 0.00 0.00 -17.99 -5.78 -15.69

Structure Therapeutics Quarterly Data
Dec20 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.24 -2.55 -4.67 -15.69 -12.75

GPCR vs PBLS, IDYA, ELVN: EV-to-OCF Comparison

For the Biotechnology subindustry, Structure Therapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Structure Therapeutics EV-to-OCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Structure Therapeutics's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where Structure Therapeutics's EV-to-OCF falls into.


GPCR
32GF Score
Structure Therapeutics Inc GPCR
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Structure Therapeutics EV-to-OCF Calculation

Structure Therapeutics's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=2157.874/-154.736
=-13.95

Structure Therapeutics's current Enterprise Value is $2,157.87 Mil.
Structure Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-154.74 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of -13.95 mean?
Structure Therapeutics (GPCR) has a EV-to-OCF of -13.95 as of Jul. 23, 2026. According to the industry distribution chart, Structure Therapeutics ranks #337 out of 1411 companies in the Biotechnology industry, placing it in the top 23.9%.
Is Structure Therapeutics' EV-to-OCF too high?
Structure Therapeutics' current EV-to-OCF is -13.95. Based on the distribution chart, Structure Therapeutics ranks #337 out of 1411 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Structure Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Structure Therapeutics' EV-to-OCF compare to PBLS and IDYA?
According to the Biotechnology industry distribution chart, Structure Therapeutics ranks #337 out of 1411 companies for EV-to-OCF. This places Structure Therapeutics in the top 24% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Structure Therapeutics's current EV-to-OCF is -13.95. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Structure Therapeutics stock overvalued right now?
Structure Therapeutics (GPCR) has a current EV-to-OCF of -13.95. The current EV-to-OCF is -13.95. Structure Therapeutics' overall GF Score™ is 32/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Structure Therapeutics (GPCR), the current EV-to-OCF is -13.95 as of Jul. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Structure Therapeutics Business Description

Address 601 Gateway Boulevard, Suite 900, South San Francisco, CA, USA, 94080
Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.
32GF Score

Get the complete analysis for GPCR

EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$50.74
Price