GPCR (Structure Therapeutics) Enterprise Value: $2,145.08 Mil (As of Jul. 23, 2026) ***

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GPCR Structure Therapeutics Inc GPCR
32 GF Score
Price $50.62
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What is Structure Therapeutics Enterprise Value?

Structure Therapeutics GPCR +0.35% 32 Enterprise Value is $2,145.08 Mil as of Jul. 23, 2026. GuruFocus rates GPCR with a GF Score™ of 32/100.

Think of Enterprise Value as the theoretical takeover price. It is more comprehensive than market capitalization (Market Cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Structure Therapeutics's Enterprise Value is $2,145.08 Mil. Structure Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-219.88 Mil. Therefore, Structure Therapeutics's EV-to-EBIT ratio for today is -9.76.

EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA. As of today, Structure Therapeutics's Enterprise Value is $2,145.08 Mil. Structure Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-218.24 Mil. Therefore, Structure Therapeutics's EV-to-EBITDA ratio for today is -9.83.

EV-to-Revenue is calculated as Enterprise Value divided by its Revenue. As of today, Structure Therapeutics's Enterprise Value is $2,145.08 Mil. Structure Therapeutics's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 was $0.00 Mil. Therefore, Structure Therapeutics's EV-to-Revenue ratio for today is .

EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations. As of today, Structure Therapeutics's Enterprise Value is $2,145.08 Mil. Structure Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-154.74 Mil. Therefore, Structure Therapeutics's EV-to-OCF ratio for today is -13.86.

EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow. As of today, Structure Therapeutics's Enterprise Value is $2,145.08 Mil. Structure Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-159.22 Mil. Therefore, Structure Therapeutics's EV-to-FCF ratio for today is -13.47.

*** Please note that the current Enterprise Value is calculated using the current market capitalization and the most recently available financial data. If key financial fields—Long-Term Debt & Capital Lease Obligation and Short-Term Debt & Capital Lease Obligation—are recorded as null in the latest reporting period, our data vendor will default to using data from the prior period with valid entries.


Structure Therapeutics  (NAS:GPCR) Enterprise Value Explanation

When an investor buy a company, the investor needs to pay not only the common shares, he/she also needs to pay the shareholders of Preferred Stocks. He also assumes the debt of the company, and receives the cash on the company's balance sheet.

If a company has more cash than debt, the investor actually pays less than the Market Cap because he immediately owns the cash once the transaction goes through.

The market value of Preferred Stock needs to be added to the market value of common stocks in the calculation of Enterprise Value.

For the companies with the same Market Cap, the smaller the Enterprise Value is, the cheaper the company is.

Enterprise Value can be negative when the company's net cash is more than its Market Cap. In this case the investor is basically getting the company for free and get paid for that.

1. EV-to-EBIT is calculated as Enterprise Value divided by its EBIT.

Structure Therapeutics's EV-to-EBIT for today is

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=2145.081/-219.877
=-9.76

Structure Therapeutics's current Enterprise Value is $2,145.08 Mil.
Structure Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-219.88 Mil.

2. EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA.

Structure Therapeutics's EV-to-EBITDA for today is:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA(TTM)
=2145.081/-218.242
=-9.83

Structure Therapeutics's current Enterprise Value is $2,145.08 Mil.
Structure Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-218.24 Mil.

3. EV-to-Revenue is calculated as Enterprise Value divided by its Revenue.

Structure Therapeutics's EV-to-Revenue for today is:

EV-to-Revenue=Enterprise Value (Today)/Revenue (TTM)
=2145.081/0
=

Structure Therapeutics's current Enterprise Value is $2,145.08 Mil.
Structure Therapeutics's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $0.00 Mil.

4. EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations.

Structure Therapeutics's EV-to-OCF for today is:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=2145.081/-154.736
=-13.86

Structure Therapeutics's current Enterprise Value is $2,145.08 Mil.
Structure Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-154.74 Mil.

5. EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow.

Structure Therapeutics's EV-to-FCF for today is:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=2145.081/-159.218
=-13.47

Structure Therapeutics's current Enterprise Value is $2,145.08 Mil.
Structure Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-159.22 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Structure Therapeutics Enterprise Value Related Terms


Structure Therapeutics Enterprise Value Historical Data

* Premium members only.

The historical data trend for Structure Therapeutics's Enterprise Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Structure Therapeutics Enterprise Value Chart

Structure Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Enterprise Value
Get a 7-Day Free Trial 0.00 0.00 1,429.68 673.97 3,487.07

Structure Therapeutics Quarterly Data
Dec20 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Enterprise Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 166.67 415.12 907.03 3,487.07 1,972.81

GPCR vs PBLS, IDYA, ELVN: Enterprise Value Comparison

For the Biotechnology subindustry, Structure Therapeutics's Enterprise Value, along with its competitors' market caps and Enterprise Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Structure Therapeutics Enterprise Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Structure Therapeutics's Enterprise Value distribution charts can be found below:

* The bar in red indicates where Structure Therapeutics's Enterprise Value falls into.


GPCR
32GF Score
Structure Therapeutics Inc GPCR
Enterprise Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Structure Therapeutics Enterprise Value Calculation

Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

Structure Therapeutics's Enterprise Value for the fiscal year that ended in Dec. 2025 is calculated as

Structure Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 is calculated as

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Enterprise Value →
What does a Enterprise Value of $2,145.08 Mil mean?
Structure Therapeutics (GPCR) has a Enterprise Value of $2,145.08 Mil as of Jul. 23, 2026. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Structure Therapeutics and its competitors.
Is Structure Therapeutics' Enterprise Value too high?
Structure Therapeutics' current Enterprise Value is $2,145.08 Mil. Overall, Structure Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Structure Therapeutics' Enterprise Value compare to PBLS and IDYA?
Structure Therapeutics' Enterprise Value of $2,145.08 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Enterprise Value for a Biotechnology company?
A good Enterprise Value depends on the Biotechnology industry context. However, Enterprise Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Enterprise Value mean?
A high Enterprise Value can signal that a stock is expensive relative to its fundamentals. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Structure Therapeutics and its competitors. Structure Therapeutics's current Enterprise Value is $2,145.08 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Structure Therapeutics stock overvalued right now?
Structure Therapeutics (GPCR) has a current Enterprise Value of $2,145.08 Mil. The current Enterprise Value is $2,145.08 Mil. Structure Therapeutics' overall GF Score™ is 32/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Enterprise Value calculated?
Enterprise Value is calculated from a company's financial statements. For Structure Therapeutics (GPCR), the current Enterprise Value is $2,145.08 Mil as of Jul. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Structure Therapeutics Business Description

Address 601 Gateway Boulevard, Suite 900, South San Francisco, CA, USA, 94080
Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.
32GF Score

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Enterprise Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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