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IO BiotechIOBTQ EV-to-OCF is 0.15 as of Aug. 25, 2026. The stock has 1 warning sign investors should review. Among 1,409 Biotechnology companies, IO Biotech ranks worse than 74.17% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, IO Biotech's Enterprise Value is $-12.54 Mil.
IO Biotech's Cash Flow from Operations for the trailing twelve months (TTM) ended in Sep. 2025 was $-81.00 Mil. Therefore, IO Biotech's EV-to-OCF for today is 0.15.
The historical rank and industry rank for IO Biotech's EV-to-OCF or its related term are showing as below:
IOBTQ'
s EV-to-OCF Range Over the Past 10 Years
Min: 0.15 Med: 0 Max: 0.15
Current: 0.15
During the past 6 years, the highest EV-to-OCF of IO Biotech was 0.15. The lowest was 0.15. And the median was .
IOBTQ's EV-to-OCF is ranked worse than 74.17% of 1409
companies
in the Biotechnology industry
Industry Median: -3.63
vs IOBTQ: 0.15
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
IO Biotech's share price for today is $0.0001.
IO Biotech's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.350.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
IO Biotech EV-to-OCF Related Terms
IO Biotech EV-to-OCF Historical Data
* Premium members only.
The historical data trend for IO Biotech's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, IO Biotech's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
IO Biotech EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, IO Biotech's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where IO Biotech's EV-to-OCF falls into.
IO Biotech's current Enterprise Value is $-12.54 Mil.
IO Biotech's Cash Flow from Operations for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-81.00 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
IO Biotech (IOBTQ) has a EV-to-OCF of 0.15 as of Aug. 25, 2026. Over the past decade, IO Biotech's EV-to-OCF has ranged from 0.15 to 0.15. According to the industry distribution chart, IO Biotech ranks #1045 out of 1409 companies in the Biotechnology industry, placing it in the top 74.2%.
Is IO Biotech's EV-to-OCF too high?
IO Biotech's current EV-to-OCF is 0.15. Over the past 10 years, this metric has ranged from a low of 0.15 to a high of 0.15. Based on the distribution chart, IO Biotech ranks #1045 out of 1409 companies in the Biotechnology industry, which is below the industry midpoint.
How does IO Biotech's EV-to-OCF compare to RGBP and SCPX?
According to the Biotechnology industry distribution chart, IO Biotech ranks #1045 out of 1409 companies for EV-to-OCF. This places IO Biotech in the lower half of its industry. Historically, IO Biotech's own EV-to-OCF has ranged from 0.15 to 0.15 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. IO Biotech's current EV-to-OCF is 0.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is IO Biotech stock overvalued right now?
IO Biotech (IOBTQ) has a current EV-to-OCF of 0.15. The current EV-to-OCF is 0.15. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For IO Biotech (IOBTQ), the current EV-to-OCF is 0.15 as of Aug. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
IO Biotech Inc is a clinical-stage biopharmaceutical company developing novel, immune-modulating cancer vaccines based on T-win technology platform. The product candidates are designed to induce the immune system to simultaneously target and disrupt multiple pathways that regulate tumor-induced immunosuppression.
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