IO BiotechIOBTQ +27.50% PB Ratio is 0.39 as of Jun. 28, 2026. The stock has 1 warning sign investors should review. Among 1,232 Biotechnology companies, IO Biotech ranks better than 96.59% on this metric.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-06-28), IO Biotech's share price is $0.0051. IO Biotech's Book Value per Share for the quarter that ended in Sep. 2025 was $0.01. Hence, IO Biotech's PB Ratio of today is 0.39.
The historical rank and industry rank for IO Biotech's PB Ratio or its related term are showing as below:
IOBTQ'
s PB Ratio Range Over the Past 10 Years
Min: 0 Med: 0 Max: 0.39
Current: 0.39
During the past 6 years, IO Biotech's highest PB Ratio was 0.39. The lowest was 0.00. And the median was 0.00.
IOBTQ's PB Ratio is ranked better than 96.59% of 1232
companies
in the Biotechnology industry
Industry Median: 2.815
vs IOBTQ: 0.39
During the past 12 months, IO Biotech's average Book Value Per Share Growth Rate was -64.70% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -54.00% per year.
During the past 6 years, the highest 3-Year average Book Value Per Share Growth Rate of IO Biotech was -54.00% per year. The lowest was -54.00% per year. And the median was -54.00% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
IO Biotech PB Ratio Related Terms
IO Biotech PB Ratio Historical Data
* Premium members only.
The historical data trend for IO Biotech's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, IO Biotech's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
IO Biotech PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, IO Biotech's PB Ratio distribution charts can be found below:
* The bar in red indicates where IO Biotech's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
IO Biotech's PB Ratio for today is calculated as follows:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
IO Biotech (IOBTQ) has a PB Ratio of 0.39 as of Jun. 28, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on IO Biotech and its competitors. According to the industry distribution chart, IO Biotech ranks #42 out of 1232 companies in the Biotechnology industry, placing it in the top 3.4%.
Is IO Biotech's PB Ratio too high?
IO Biotech's current PB Ratio is 0.39. The Biotechnology industry median PB Ratio is 2.82. IO Biotech's value of 0.39 is 86.1% below this industry median. Based on the distribution chart, IO Biotech ranks #42 out of 1232 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers.
How does IO Biotech's PB Ratio compare to CNBX and ENDV?
According to the Biotechnology industry distribution chart, IO Biotech ranks #42 out of 1232 companies for PB Ratio. This places IO Biotech in the top 3% of its industry — outperforming the majority of peers. The industry median PB Ratio is 2.82. IO Biotech's value of 0.39 is 86.1% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.82, based on 1,232 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. IO Biotech's current PB Ratio of 0.39 is 86.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on IO Biotech and its competitors. For the Biotechnology industry, the median PB Ratio is 2.82 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. IO Biotech's current PB Ratio is 0.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is IO Biotech stock overvalued right now?
IO Biotech (IOBTQ) has a current PB Ratio of 0.39. The current PB Ratio is 0.39 and 86.1% below the Biotechnology industry median of 2.82. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For IO Biotech (IOBTQ), the current PB Ratio is 0.39 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
IO Biotech Inc is a clinical-stage biopharmaceutical company developing novel, immune-modulating cancer vaccines based on T-win technology platform. The product candidates are designed to induce the immune system to simultaneously target and disrupt multiple pathways that regulate tumor-induced immunosuppression.
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