SPTX (Seaport Therapeutics) Enterprise Value: $969.90 Mil (As of Jun. 27, 2026) ***


SPTX Seaport Therapeutics Inc SPTX
11 GF Score
Price $21.43
! 1 Warning Sign
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What is Seaport Therapeutics Enterprise Value?

Seaport Therapeutics SPTX +10.37% 11 Enterprise Value is $969.90 Mil as of Jun. 27, 2026. GuruFocus rates SPTX with a GF Score™ of 11/100. The stock has 1 warning sign investors should review.

Think of Enterprise Value as the theoretical takeover price. It is more comprehensive than market capitalization (Market Cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Seaport Therapeutics's Enterprise Value is $969.90 Mil. Seaport Therapeutics does not have enough years/quarters to calculate its EBIT for the trailing twelve months (TTM) ended in Dec. 2025. Therefore, GuruFocus does not calculate Seaport Therapeutics's EV-to-EBIT at this moment.

EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA. As of today, Seaport Therapeutics's Enterprise Value is $969.90 Mil. Seaport Therapeutics does not have enough years/quarters to calculate its EBITDA for the trailing twelve months (TTM) ended in Dec. 2025. Therefore, GuruFocus does not calculate Seaport Therapeutics's EV-to-EBITDA at this moment.

EV-to-Revenue is calculated as Enterprise Value divided by its Revenue. As of today, Seaport Therapeutics's Enterprise Value is $969.90 Mil. Seaport Therapeutics does not have enough years/quarters to calculate its Revenue for the trailing twelve months (TTM) ended in Dec. 2025. Therefore, GuruFocus does not calculate Seaport Therapeutics's EV-to-Revenue at this moment.

EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations. As of today, Seaport Therapeutics's Enterprise Value is $969.90 Mil. Seaport Therapeutics does not have enough years/quarters to calculate its Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025. Therefore, GuruFocus does not calculate Seaport Therapeutics's EV-to-OCF at this moment.

EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow. As of today, Seaport Therapeutics's Enterprise Value is $969.90 Mil. Seaport Therapeutics does not have enough years/quarters to calculate its Free Cash Flow for the trailing twelve months (TTM) ended in Dec. 2025. Therefore, GuruFocus does not calculate Seaport Therapeutics's EV-to-FCF at this moment.

*** Please note that the current Enterprise Value is calculated using the current market capitalization and the most recently available financial data. If key financial fields—Long-Term Debt & Capital Lease Obligation and Short-Term Debt & Capital Lease Obligation—are recorded as null in the latest reporting period, our data vendor will default to using data from the prior period with valid entries.


Seaport Therapeutics  (NAS:SPTX) Enterprise Value Explanation

When an investor buy a company, the investor needs to pay not only the common shares, he/she also needs to pay the shareholders of Preferred Stocks. He also assumes the debt of the company, and receives the cash on the company's balance sheet.

If a company has more cash than debt, the investor actually pays less than the Market Cap because he immediately owns the cash once the transaction goes through.

The market value of Preferred Stock needs to be added to the market value of common stocks in the calculation of Enterprise Value.

For the companies with the same Market Cap, the smaller the Enterprise Value is, the cheaper the company is.

Enterprise Value can be negative when the company's net cash is more than its Market Cap. In this case the investor is basically getting the company for free and get paid for that.


Seaport Therapeutics Enterprise Value Related Terms


Seaport Therapeutics Enterprise Value Historical Data

* Premium members only.

The historical data trend for Seaport Therapeutics's Enterprise Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Seaport Therapeutics Enterprise Value Chart

Seaport Therapeutics Annual Data
Trend Dec24 Dec25
Enterprise Value
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Seaport Therapeutics Semi-Annual Data
Dec24 Dec25
Enterprise Value 0.00 0.00

SPTX vs LXRX, DRTS, MGTX: Enterprise Value Comparison

For the Biotechnology subindustry, Seaport Therapeutics's Enterprise Value, along with its competitors' market caps and Enterprise Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Seaport Therapeutics Enterprise Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Seaport Therapeutics's Enterprise Value distribution charts can be found below:

* The bar in red indicates where Seaport Therapeutics's Enterprise Value falls into.


SPTX
11GF Score
Seaport Therapeutics Inc SPTX
Enterprise Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Seaport Therapeutics Enterprise Value Calculation

Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

Seaport Therapeutics's Enterprise Value for the fiscal year that ended in Dec. 2025 is calculated as

Seaport Therapeutics's Enterprise Value for the quarter that ended in Dec. 2025 is calculated as

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Enterprise Value →
What does a Enterprise Value of $969.90 Mil mean?
Seaport Therapeutics (SPTX) has a Enterprise Value of $969.90 Mil as of Jun. 27, 2026. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Seaport Therapeutics and its competitors.
Is Seaport Therapeutics' Enterprise Value too high?
Seaport Therapeutics' current Enterprise Value is $969.90 Mil. Overall, Seaport Therapeutics has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does Seaport Therapeutics' Enterprise Value compare to LXRX and DRTS?
Seaport Therapeutics' Enterprise Value of $969.90 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Enterprise Value for a Biotechnology company?
A good Enterprise Value depends on the Biotechnology industry context. However, Enterprise Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Enterprise Value mean?
A high Enterprise Value can signal that a stock is expensive relative to its fundamentals. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Seaport Therapeutics and its competitors. Seaport Therapeutics's current Enterprise Value is $969.90 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Seaport Therapeutics stock overvalued right now?
Seaport Therapeutics (SPTX) has a current Enterprise Value of $969.90 Mil. The current Enterprise Value is $969.90 Mil. Seaport Therapeutics' overall GF Score™ is 11/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Enterprise Value calculated?
Enterprise Value is calculated from a company's financial statements. For Seaport Therapeutics (SPTX), the current Enterprise Value is $969.90 Mil as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Seaport Therapeutics Business Description

Address 101 Seaport Boulevard, Floor 12, Boston, MA, USA, 02210
Seaport Therapeutics Inc is a clinical-stage therapeutics company. The company focuses on invention and development of new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. The company identified clinically validated mechanisms with established efficacy and safety profiles, historically limited by high first-pass metabolism, low bioavailability, and side effects. The company's pipeline products are based on Glyph, company's lymphatic-targeting prodrug technology is designed to bypass first-pass metabolism and thereby enhance a drug's oral bioavailability and reduce side effects.
11GF Score

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