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OnKure TherapeuticsOKUR -3.29%14 EV-to-FCF is 0.44 as of Jul. 14, 2026. GuruFocus rates OKUR with a GF Score™ of 14/100. The stock has 1 warning sign investors should review. Among 335 Biotechnology companies, OnKure Therapeutics ranks better than 85.37% on this metric.
EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, OnKure Therapeutics's Enterprise Value is $-22.44 Mil.
OnKure Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-50.79 Mil. Therefore, OnKure Therapeutics's EV-to-FCF for today is 0.44.
The historical rank and industry rank for OnKure Therapeutics's EV-to-FCF or its related term are showing as below:
OKUR'
s EV-to-FCF Range Over the Past 10 Years
Min: 0 Med: 0 Max: 0.44
Current: 0.44
During the past 4 years, the highest EV-to-FCF of OnKure Therapeutics was 0.44. The lowest was 0.00. And the median was 0.00.
OKUR's EV-to-FCF is ranked better than 85.37% of 335
companies
in the Biotechnology industry
Industry Median: 15.34
vs OKUR: 0.44
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
OnKure Therapeutics's PE Ratio (TTM) for today is calculated as:
OnKure Therapeutics's share price for today is $4.12.
OnKure Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-4.330.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.
OnKure Therapeutics EV-to-FCF Related Terms
OnKure Therapeutics EV-to-FCF Historical Data
* Premium members only.
The historical data trend for OnKure Therapeutics's EV-to-FCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, OnKure Therapeutics's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
OnKure Therapeutics EV-to-FCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, OnKure Therapeutics's EV-to-FCF distribution charts can be found below:
* The bar in red indicates where OnKure Therapeutics's EV-to-FCF falls into.
OnKure Therapeutics's current Enterprise Value is $-22.44 Mil.
OnKure Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-50.79 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OnKure Therapeutics (OKUR) has a EV-to-FCF of 0.44 as of Jul. 14, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on OnKure Therapeutics and its competitors. According to the industry distribution chart, OnKure Therapeutics ranks #49 out of 335 companies in the Biotechnology industry, placing it in the top 14.6%.
Is OnKure Therapeutics' EV-to-FCF too high?
OnKure Therapeutics' current EV-to-FCF is 0.44. The Biotechnology industry median EV-to-FCF is 15.34. OnKure Therapeutics' value of 0.44 is 97.1% below this industry median. Based on the distribution chart, OnKure Therapeutics ranks #49 out of 335 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, OnKure Therapeutics has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does OnKure Therapeutics' EV-to-FCF compare to ANTX and PLX?
According to the Biotechnology industry distribution chart, OnKure Therapeutics ranks #49 out of 335 companies for EV-to-FCF. This places OnKure Therapeutics in the top 15% of its industry — outperforming the majority of peers. The industry median EV-to-FCF is 15.34. OnKure Therapeutics' value of 0.44 is 97.1% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 15.34, based on 335 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. OnKure Therapeutics's current EV-to-FCF of 0.44 is 97.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on OnKure Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-FCF is 15.34 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OnKure Therapeutics's current EV-to-FCF is 0.44. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OnKure Therapeutics stock overvalued right now?
OnKure Therapeutics (OKUR) has a current EV-to-FCF of 0.44. The current EV-to-FCF is 0.44 and 97.1% below the Biotechnology industry median of 15.34. OnKure Therapeutics' overall GF Score™ is 14/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For OnKure Therapeutics (OKUR), the current EV-to-FCF is 0.44 as of Jul. 14, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
OnKure Therapeutics Inc is a clinical-stage biopharmaceutical company focused on discovering and developing precision medicines that target biologically validated drivers of cancers underserved by available therapies. The company uses a structure-based drug design platform to develop a pipeline of drug candidates aimed at optimizing efficacy and tolerability. The company has multiple programs focused on targeting oncogenic PI3K?. Its flagship program is OKI-219. The company operates in one operating segment: clinical research.
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