InSilico Medicine Cayman TopCo (FRA:O15) FCF Margin %: -145.64% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FRA:O15 InSilico Medicine Cayman TopCo FRA:O15
20 GF Score
Price €5.25
! 3 Warning Signs
View Full Analysis

What is InSilico Medicine Cayman TopCo FCF Margin %?

InSilico Medicine Cayman TopCo FRA:O15 +3.96% 20 FCF Margin % is -145.64% as of Dec. 2025. GuruFocus rates FRA:O15 with a GF Score™ of 20/100. The stock has 3 warning signs investors should review. Among 2,821 Software companies, InSilico Medicine Cayman TopCo ranks worse than 91.81% on this metric.

FCF Margin % is calculated as Free Cash Flow divided by its Revenue. InSilico Medicine Cayman TopCo's Free Cash Flow for the six months ended in Dec. 2025 was €-35.80 Mil. InSilico Medicine Cayman TopCo's Revenue for the six months ended in Dec. 2025 was €24.58 Mil. Therefore, InSilico Medicine Cayman TopCo's FCF Margin % for the quarter that ended in Dec. 2025 was -145.64%.

As of today, InSilico Medicine Cayman TopCo's current FCF Yield % is -2.26%.

The historical rank and industry rank for InSilico Medicine Cayman TopCo's FCF Margin % or its related term are showing as below:

FRA:O15' s FCF Margin % Range Over the Past 10 Years
Min: -194.84   Med: -104.87   Max: -63.6
Current: -141.76


During the past 4 years, the highest FCF Margin % of InSilico Medicine Cayman TopCo was -63.60%. The lowest was -194.84%. And the median was -104.87%.

FRA:O15's FCF Margin % is ranked worse than
91.81% of 2821 companies
in the Software industry
Industry Median: 2 vs FRA:O15: -141.76


InSilico Medicine Cayman TopCo FCF Margin % Related Terms


InSilico Medicine Cayman TopCo FCF Margin % Historical Data

* Premium members only.

The historical data trend for InSilico Medicine Cayman TopCo's FCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

InSilico Medicine Cayman TopCo FCF Margin % Chart

InSilico Medicine Cayman TopCo Annual Data
Trend Dec22 Dec23 Dec24 Dec25
FCF Margin %
-194.83 -63.60 -67.95 -141.79

InSilico Medicine Cayman TopCo Semi-Annual Data
Dec22 Dec23 Jun24 Dec24 Jun25 Dec25
FCF Margin % Get a 7-Day Free Trial 0.00 -55.87 -95.53 -137.75 -145.64

FRA:O15 vs MSFT, ORCL, PLTR: FCF Margin % Comparison

For the Software - Infrastructure subindustry, InSilico Medicine Cayman TopCo's FCF Margin %, along with its competitors' market caps and FCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


InSilico Medicine Cayman TopCo FCF Margin % vs Software Industry

For the Software industry and Technology sector, InSilico Medicine Cayman TopCo's FCF Margin % distribution charts can be found below:

* The bar in red indicates where InSilico Medicine Cayman TopCo's FCF Margin % falls into.


FRA:O15
20GF Score
InSilico Medicine Cayman TopCo FRA:O15
FCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

InSilico Medicine Cayman TopCo FCF Margin % Calculation

FCF margin is the ratio of Free Cash Flow divided by net sales or Revenue, usually presented in percent.

InSilico Medicine Cayman TopCo's FCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

FCF Margin=Free Cash Flow (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-68.099/48.028
=-141.79 %

InSilico Medicine Cayman TopCo's FCF Margin for the quarter that ended in Dec. 2025 is calculated as

FCF Margin=Free Cash Flow (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-35.8/24.581
=-145.64 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about FCF Margin % →
What does a FCF Margin % of -145.64% mean?
InSilico Medicine Cayman TopCo (FRA:O15) has a FCF Margin % of -145.64% as of Dec. 2025. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on InSilico Medicine Cayman TopCo and its competitors. According to the industry distribution chart, InSilico Medicine Cayman TopCo ranks #2590 out of 2821 companies in the Software industry, placing it in the top 91.8%.
Is InSilico Medicine Cayman TopCo's FCF Margin % too high?
InSilico Medicine Cayman TopCo's current FCF Margin % is -145.64%. Based on the distribution chart, InSilico Medicine Cayman TopCo ranks #2590 out of 2821 companies in the Software industry, which is in the bottom quartile relative to peers. Overall, InSilico Medicine Cayman TopCo has a GF Score™ of 20/100, reflecting its overall financial health beyond just this single metric.
How does InSilico Medicine Cayman TopCo's FCF Margin % compare to MSFT and ORCL?
According to the Software industry distribution chart, InSilico Medicine Cayman TopCo ranks #2590 out of 2821 companies for FCF Margin %. This places InSilico Medicine Cayman TopCo in the lower half of its industry. The industry median FCF Margin % is 2.00. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good FCF Margin % for a Software company?
The median FCF Margin % among Software companies is 2.00, based on 2,821 companies in the industry. Companies in the top quartile (top 25%) have a FCF Margin % significantly above this median, while those in the bottom quartile fall well below. However, FCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high FCF Margin % mean?
A high FCF Margin % can signal that a stock is expensive relative to its fundamentals. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on InSilico Medicine Cayman TopCo and its competitors. For the Software industry, the median FCF Margin % is 2.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. InSilico Medicine Cayman TopCo's current FCF Margin % is -145.64%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is InSilico Medicine Cayman TopCo stock overvalued right now?
InSilico Medicine Cayman TopCo (FRA:O15) has a current FCF Margin % of -145.64%. The current FCF Margin % is -145.64%. InSilico Medicine Cayman TopCo's overall GF Score™ is 20/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is FCF Margin % calculated?
FCF Margin % is calculated from a company's financial statements. For InSilico Medicine Cayman TopCo (FRA:O15), the current FCF Margin % is -145.64% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

InSilico Medicine Cayman TopCo Business Description

Other Exchanges 03696:Hong Kong
Address Hong Kong Science Park, Unit 310, 3rd Floor, Building 8W, Phase 2, Pak Shek Kok, New Territories, Hong Kong, HKG
InSilico Medicine Cayman TopCo is engaged in applying artificial intelligence (AI) solutions to drug discovery and development by leveraging its proprietary platforms. It has generated multiple clinical-stage or IND-enabling assets using Pharma.AI, an AI-enabled platform that supports drug discovery and development activities. The company operates under a project-based business model, deriving revenue from out-licensing and collaboration arrangements. Geographically, the company generates revenue from multiple countries, with the majority of the revenue coming from United States.
20GF Score

Get the complete analysis for FRA:O15

FCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€5.25
Price