InSilico Medicine Cayman TopCo (FRA:O15) ROIC %: -16.29% (As of Dec. 2025)

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FRA:O15 InSilico Medicine Cayman TopCo FRA:O15
20 GF Score
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What is InSilico Medicine Cayman TopCo ROIC %?

InSilico Medicine Cayman TopCo FRA:O15 +3.96% 20 ROIC % is -16.29% as of Dec. 2025. GuruFocus rates FRA:O15 with a GF Score™ of 20/100. The stock has 3 warning signs investors should review.

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. InSilico Medicine Cayman TopCo's annualized return on invested capital (ROIC %) for the quarter that ended in Dec. 2025 was -16.29%.

As of today (2026-08-27), InSilico Medicine Cayman TopCo's WACC % is 10.64%. InSilico Medicine Cayman TopCo's ROIC % is -10.65% (calculated using TTM income statement data). InSilico Medicine Cayman TopCo earns returns that do not match up to its cost of capital. It will destroy value as it grows.


InSilico Medicine Cayman TopCo  (FRA:O15) ROIC % Explanation

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROIC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, InSilico Medicine Cayman TopCo's WACC % is 10.64%. InSilico Medicine Cayman TopCo's ROIC % is -10.65% (calculated using TTM income statement data). InSilico Medicine Cayman TopCo earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROIC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


InSilico Medicine Cayman TopCo ROIC % Related Terms


InSilico Medicine Cayman TopCo ROIC % Historical Data

* Premium members only.

The historical data trend for InSilico Medicine Cayman TopCo's ROIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

InSilico Medicine Cayman TopCo ROIC % Chart

InSilico Medicine Cayman TopCo Annual Data
Trend Dec22 Dec23 Dec24 Dec25
ROIC %
-11.80 -11.66 -4.16 -13.44

InSilico Medicine Cayman TopCo Semi-Annual Data
Dec22 Dec23 Jun24 Dec24 Jun25 Dec25
ROIC % Get a 7-Day Free Trial 0.00 1.16 -9.62 -5.08 -16.29

FRA:O15 vs MSFT, ORCL, PLTR: ROIC % Comparison

For the Software - Infrastructure subindustry, InSilico Medicine Cayman TopCo's ROIC %, along with its competitors' market caps and ROIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


InSilico Medicine Cayman TopCo ROIC % vs Software Industry

For the Software industry and Technology sector, InSilico Medicine Cayman TopCo's ROIC % distribution charts can be found below:

* The bar in red indicates where InSilico Medicine Cayman TopCo's ROIC % falls into.


FRA:O15
20GF Score
InSilico Medicine Cayman TopCo FRA:O15
ROIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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InSilico Medicine Cayman TopCo ROIC % Calculation

InSilico Medicine Cayman TopCo's annualized Return on Invested Capital (ROIC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROIC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-52.987 * ( 1 - 0% )/( (759.759 + 28.76)/ 2 )
=-52.987/394.2595
=-13.44 %

where

Invested Capital(A: Dec. 2024 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=137.522 - 20.915 - ( 120.275 - max(0, 770.558 - 127.406+120.275))
=759.759

InSilico Medicine Cayman TopCo's annualized Return on Invested Capital (ROIC %) for the quarter that ended in Dec. 2025 is calculated as:

ROIC % (Q: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Jun. 2025 ) + Invested Capital (Q: Dec. 2025 ))/ count )
=-67.062 * ( 1 - 0% )/( (794.57 + 28.76)/ 2 )
=-67.062/411.665
=-16.29 %

where

Note: The Operating Income data used here is two times the semi-annual (Dec. 2025) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROIC % →
What does a ROIC % of -16.29% mean?
InSilico Medicine Cayman TopCo (FRA:O15) has a ROIC % of -16.29% as of Dec. 2025. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on InSilico Medicine Cayman TopCo and its competitors.
Is InSilico Medicine Cayman TopCo's ROIC % too high?
InSilico Medicine Cayman TopCo's current ROIC % is -16.29%. Overall, InSilico Medicine Cayman TopCo has a GF Score™ of 20/100, reflecting its overall financial health beyond just this single metric.
How does InSilico Medicine Cayman TopCo's ROIC % compare to MSFT and ORCL?
InSilico Medicine Cayman TopCo's ROIC % of -16.29% can be compared against companies in the Software industry. The industry median ROIC % is 3.57. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROIC % for a Software company?
The median ROIC % among Software companies is 3.57, based on 2,835 companies in the industry. Companies in the top quartile (top 25%) have a ROIC % significantly above this median, while those in the bottom quartile fall well below. However, ROIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROIC % mean?
A high ROIC % can signal that a stock is expensive relative to its fundamentals. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on InSilico Medicine Cayman TopCo and its competitors. For the Software industry, the median ROIC % is 3.57 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. InSilico Medicine Cayman TopCo's current ROIC % is -16.29%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is InSilico Medicine Cayman TopCo stock overvalued right now?
InSilico Medicine Cayman TopCo (FRA:O15) has a current ROIC % of -16.29%. The current ROIC % is -16.29%. InSilico Medicine Cayman TopCo's overall GF Score™ is 20/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROIC % calculated?
ROIC % is calculated from a company's financial statements. For InSilico Medicine Cayman TopCo (FRA:O15), the current ROIC % is -16.29% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

InSilico Medicine Cayman TopCo Business Description

Other Exchanges 03696:Hong Kong
Address Hong Kong Science Park, Unit 310, 3rd Floor, Building 8W, Phase 2, Pak Shek Kok, New Territories, Hong Kong, HKG
InSilico Medicine Cayman TopCo is engaged in applying artificial intelligence (AI) solutions to drug discovery and development by leveraging its proprietary platforms. It has generated multiple clinical-stage or IND-enabling assets using Pharma.AI, an AI-enabled platform that supports drug discovery and development activities. The company operates under a project-based business model, deriving revenue from out-licensing and collaboration arrangements. Geographically, the company generates revenue from multiple countries, with the majority of the revenue coming from United States.
20GF Score

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