Newron Pharmaceuticals SpA (FRA:NP5) Piotroski F-Score: 4 (As of Jun. 25, 2026) — Near Median


FRA:NP5 Newron Pharmaceuticals SpA FRA:NP5
65 GF Score
Price €13.55
GF Value €13.83
Valuation Fairly Valued
! 5 Warning Signs
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What is Newron Pharmaceuticals SpA Piotroski F-Score?

Newron Pharmaceuticals SpA FRA:NP5 +1.50% 65 Piotroski F-Score is 4 as of Jun. 25, 2026, which is at its 10-year median of 4.00. GuruFocus rates FRA:NP5 with a GF Score™ of 65/100 and a GF Value™ of €13.83 (Fairly Valued). The stock has 5 warning signs investors should review. Among 1,342 Biotechnology companies, Newron Pharmaceuticals SpA ranks better than 74.22% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Newron Pharmaceuticals SpA has an F-score of 4 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for Newron Pharmaceuticals SpA's Piotroski F-Score or its related term are showing as below:

FRA:NP5' s Piotroski F-Score Range Over the Past 10 Years
Min: 1   Med: 4   Max: 5
Current: 4

During the past 13 years, the highest Piotroski F-Score of Newron Pharmaceuticals SpA was 5. The lowest was 1. And the median was 4.

Newron Pharmaceuticals SpA  (FRA:NP5) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Newron Pharmaceuticals SpA Piotroski F-Score Related Terms


Newron Pharmaceuticals SpA Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Newron Pharmaceuticals SpA's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Newron Pharmaceuticals SpA Piotroski F-Score Chart

Newron Pharmaceuticals SpA Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 5.00 3.00 4.00 4.00 4.00

Newron Pharmaceuticals SpA Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 4.00 0.00 4.00 0.00 4.00

FRA:NP5 vs VRTX, REGN, ALNY: Piotroski F-Score Comparison

For the Biotechnology subindustry, Newron Pharmaceuticals SpA's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Newron Pharmaceuticals SpA Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Newron Pharmaceuticals SpA's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Newron Pharmaceuticals SpA's Piotroski F-Score falls into.


FRA:NP5
65GF Score
Newron Pharmaceuticals SpA FRA:NP5
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was €-13.24 Mil.
Cash Flow from Operations was €32.35 Mil.
Revenue was €19.13 Mil.
Gross Profit was €19.13 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (63.908 + 40.055) / 2 = €51.9815 Mil.
Total Assets at the begining of this year (Dec24) was €63.91 Mil.
Long-Term Debt & Capital Lease Obligation was €0.58 Mil.
Total Current Assets was €38.08 Mil.
Total Current Liabilities was €50.13 Mil.
Net Income was €15.84 Mil.

Revenue was €51.39 Mil.
Gross Profit was €51.39 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (25.866 + 63.908) / 2 = €44.887 Mil.
Total Assets at the begining of last year (Dec23) was €25.87 Mil.
Long-Term Debt & Capital Lease Obligation was €36.92 Mil.
Total Current Assets was €61.10 Mil.
Total Current Liabilities was €23.51 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Newron Pharmaceuticals SpA's current Net Income (TTM) was -13.24. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Newron Pharmaceuticals SpA's current Cash Flow from Operations (TTM) was 32.35. ==> Positive ==> Score 1.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-13.239/63.908
=-0.20715716

ROA (Last Year)=Net Income/Total Assets (Dec23)
=15.843/25.866
=0.6125029

Newron Pharmaceuticals SpA's return on assets of this year was -0.20715716. Newron Pharmaceuticals SpA's return on assets of last year was 0.6125029. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Newron Pharmaceuticals SpA's current Net Income (TTM) was -13.24. Newron Pharmaceuticals SpA's current Cash Flow from Operations (TTM) was 32.35. ==> 32.35 > -13.24 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=0.583/51.9815
=0.01121553

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=36.916/44.887
=0.82242075

Newron Pharmaceuticals SpA's gearing of this year was 0.01121553. Newron Pharmaceuticals SpA's gearing of last year was 0.82242075. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=38.079/50.131
=0.75958987

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=61.104/23.506
=2.59950651

Newron Pharmaceuticals SpA's current ratio of this year was 0.75958987. Newron Pharmaceuticals SpA's current ratio of last year was 2.59950651. ==> Last year's current ratio is higher ==> Score 0.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Newron Pharmaceuticals SpA's number of shares in issue this year was 19.963. Newron Pharmaceuticals SpA's number of shares in issue last year was 20.575. ==> There is smaller number of shares in issue this year, or the same. ==> Score 1.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=19.126/19.126
=1

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=51.39/51.39
=1

Newron Pharmaceuticals SpA's gross margin of this year was 1. Newron Pharmaceuticals SpA's gross margin of last year was 1. ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=19.126/63.908
=0.29927396

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=51.39/25.866
=1.98677801

Newron Pharmaceuticals SpA's asset turnover of this year was 0.29927396. Newron Pharmaceuticals SpA's asset turnover of last year was 1.98677801. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+1+0+1+1+0+1+0+0
=4

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Newron Pharmaceuticals SpA has an F-score of 4 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 4 mean?
Newron Pharmaceuticals SpA (FRA:NP5) has a Piotroski F-Score of 4 as of Jun. 25, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Newron Pharmaceuticals SpA and its competitors. This is near median its historical median of 4.00. Over the past decade, Newron Pharmaceuticals SpA's Piotroski F-Score has ranged from 1.00 to 5.00. According to the industry distribution chart, Newron Pharmaceuticals SpA ranks #346 out of 1342 companies in the Biotechnology industry, placing it in the top 25.8%.
Is Newron Pharmaceuticals SpA's Piotroski F-Score too high?
Newron Pharmaceuticals SpA's current Piotroski F-Score of 4 is near median its 10-year median of 4.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 5.00. The Biotechnology industry median Piotroski F-Score is 3.00. Newron Pharmaceuticals SpA's value of 4 is 33.3% above this industry median. Based on the distribution chart, Newron Pharmaceuticals SpA ranks #346 out of 1342 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Newron Pharmaceuticals SpA has a GF Score™ of 65/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Newron Pharmaceuticals SpA's Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Newron Pharmaceuticals SpA ranks #346 out of 1342 companies for Piotroski F-Score. This puts Newron Pharmaceuticals SpA in the upper half of its industry. The industry median Piotroski F-Score is 3.00. Newron Pharmaceuticals SpA's value of 4 is 33.3% above this benchmark. Historically, Newron Pharmaceuticals SpA's own Piotroski F-Score has ranged from 1.00 to 5.00 over the past decade. While the company's 10-year median is 4.00 vs. the industry median of 3.00, Newron Pharmaceuticals SpA has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,342 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Newron Pharmaceuticals SpA's current Piotroski F-Score of 4 is 33.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Newron Pharmaceuticals SpA and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Newron Pharmaceuticals SpA's current Piotroski F-Score is 4, which is near median its own 10-year median of 4.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Newron Pharmaceuticals SpA stock overvalued right now?
Based on GuruFocus' analysis, Newron Pharmaceuticals SpA (FRA:NP5) is currently considered Fairly Valued. The stock's GF Value™ is €13.83, compared to a current price of €13.55 — trading 2% below its estimated fair value. The current Piotroski F-Score is 4, which is near median its 10-year median of 4.00 and 33.3% above the Biotechnology industry median of 3.00. Newron Pharmaceuticals SpA's overall GF Score™ is 65/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Newron Pharmaceuticals SpA (FRA:NP5), the current Piotroski F-Score is 4 as of Jun. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Newron Pharmaceuticals SpA (FRA:NP5) Overvalued in 2026?

Based on GuruFocus' analysis, Newron Pharmaceuticals SpA stock appears to be undervalued. The current stock price of €13.55 is trading 2% below its estimated GF Value™ of €13.83. GuruFocus considers Newron Pharmaceuticals SpA to be Fairly Valued.

Key valuation signals for FRA:NP5:

  • Piotroski F-Score: 4 (near median its 10-year median of 4.00)
  • GF Value™: €13.83 vs. price of €13.55 (2% below fair value)
  • GF Score™: 65/100 with 5 warning signs
  • Industry Position: 33.3% above the Biotechnology median (#346 of 1342)

No single metric tells the full story. See the FRA:NP5 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Newron Pharmaceuticals SpA Business Description

Address Via Antonio Meucci 3, Bresso, Milan, ITA, 20091
Newron Pharmaceuticals SpA is a Italy-based clinical-stage biopharmaceutical company. It focuses on the discovery and development of pharmaceutical products. The Company is engaged in discovering and developing new therapies for diseases of the Central Nervous System (CNS) and pain. The Company undertakes phase III trials with safinamide molecule for the treatment of patients with Parkinson's disease. Newron Pharmaceuticals SpA develops ralfinamide, a molecule for the treatment of neuropathic pain. Geographically the research and development activities are performed in Italy and the United States.
65GF Score

Get the complete analysis for FRA:NP5

Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€13.55
Price
€13.83
GF Value