GLSI (Greenwich LifeSciences) Piotroski F-Score: 3 (As of Jun. 24, 2026) — 50% Above Median


GLSI Greenwich LifeSciences Inc GLSI
33 GF Score
Price $21.53
! 1 Warning Sign
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What is Greenwich LifeSciences Piotroski F-Score?

Greenwich LifeSciences GLSI -6.78% 33 Piotroski F-Score is 3 as of Jun. 24, 2026, which is 50% above its 10-year median of 2.00. GuruFocus rates GLSI with a GF Score™ of 33/100. The stock has 1 warning sign investors should review. Among 1,341 Biotechnology companies, Greenwich LifeSciences ranks better than 55.11% on this metric.

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Greenwich LifeSciences has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

The historical rank and industry rank for Greenwich LifeSciences's Piotroski F-Score or its related term are showing as below:

GLSI' s Piotroski F-Score Range Over the Past 10 Years
Min: 2   Med: 2   Max: 5
Current: 3

During the past 8 years, the highest Piotroski F-Score of Greenwich LifeSciences was 5. The lowest was 2. And the median was 2.

Greenwich LifeSciences  (NAS:GLSI) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Greenwich LifeSciences Piotroski F-Score Related Terms


Greenwich LifeSciences Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Greenwich LifeSciences's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Greenwich LifeSciences Piotroski F-Score Chart

Greenwich LifeSciences Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial 4.00 3.00 2.00 2.00 2.00

Greenwich LifeSciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.00 2.00 2.00 2.00 3.00

GLSI vs LRMR, RGNX, PBYI: Piotroski F-Score Comparison

For the Biotechnology subindustry, Greenwich LifeSciences's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Greenwich LifeSciences Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Greenwich LifeSciences's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Greenwich LifeSciences's Piotroski F-Score falls into.


GLSI
33GF Score
Greenwich LifeSciences Inc GLSI
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
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How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Mar26) TTM:Last Year (Mar25) TTM:
Net Income was -4.025 + -4.152 + -7.923 + -5.657 = $-21.76 Mil.
Cash Flow from Operations was -2.233 + -2.671 + -3.175 + -4.702 = $-12.78 Mil.
Revenue was 0 + 0 + 0 + 0 = $0.00 Mil.
Gross Profit was 0 + 0 + 0 + 0 = $0.00 Mil.
Average Total Assets from the begining of this year (Mar25)
to the end of this year (Mar26) was
(2.751 + 3.125 + 3.807 + 6.178 + 10.505) / 5 = $5.2732 Mil.
Total Assets at the begining of this year (Mar25) was $2.75 Mil.
Long-Term Debt & Capital Lease Obligation was $0.00 Mil.
Total Current Assets was $10.51 Mil.
Total Current Liabilities was $5.24 Mil.
Net Income was -2.607 + -2.669 + -9.666 + -2.745 = $-17.69 Mil.

Revenue was 0 + 0 + 0 + 0 = $0.00 Mil.
Gross Profit was 0 + 0 + 0 + 0 = $0.00 Mil.
Average Total Assets from the begining of last year (Mar24)
to the end of last year (Mar25) was
(5.51 + 7.228 + 5.825 + 4.094 + 2.751) / 5 = $5.0816 Mil.
Total Assets at the begining of last year (Mar24) was $5.51 Mil.
Long-Term Debt & Capital Lease Obligation was $0.00 Mil.
Total Current Assets was $2.75 Mil.
Total Current Liabilities was $1.44 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Greenwich LifeSciences's current Net Income (TTM) was -21.76. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Greenwich LifeSciences's current Cash Flow from Operations (TTM) was -12.78. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Mar25)
=-21.757/2.751
=-7.90876045

ROA (Last Year)=Net Income/Total Assets (Mar24)
=-17.687/5.51
=-3.20998185

Greenwich LifeSciences's return on assets of this year was -7.90876045. Greenwich LifeSciences's return on assets of last year was -3.20998185. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Greenwich LifeSciences's current Net Income (TTM) was -21.76. Greenwich LifeSciences's current Cash Flow from Operations (TTM) was -12.78. ==> -12.78 > -21.76 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Mar26)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar25 to Mar26
=0/5.2732
=0

Gearing (Last Year: Mar25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar24 to Mar25
=0/5.0816
=0

Greenwich LifeSciences's gearing of this year was 0. Greenwich LifeSciences's gearing of last year was 0. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Mar26)=Total Current Assets/Total Current Liabilities
=10.505/5.235
=2.00668577

Current Ratio (Last Year: Mar25)=Total Current Assets/Total Current Liabilities
=2.751/1.439
=1.91174427

Greenwich LifeSciences's current ratio of this year was 2.00668577. Greenwich LifeSciences's current ratio of last year was 1.91174427. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Greenwich LifeSciences's number of shares in issue this year was 14.565. Greenwich LifeSciences's number of shares in issue last year was 13.172. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0/0
=

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0/0
=

Greenwich LifeSciences's gross margin of this year was . Greenwich LifeSciences's gross margin of last year was . ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Mar25)
=0/2.751
=0

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Mar24)
=0/5.51
=0

Greenwich LifeSciences's asset turnover of this year was 0. Greenwich LifeSciences's asset turnover of last year was 0. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+0+1+1+1+0+0+0
=3

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Greenwich LifeSciences has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 3 mean?
Greenwich LifeSciences (GLSI) has a Piotroski F-Score of 3 as of Jun. 24, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Greenwich LifeSciences and its competitors. This is 50% above median its historical median of 2.00. Over the past decade, Greenwich LifeSciences' Piotroski F-Score has ranged from 2.00 to 5.00. According to the industry distribution chart, Greenwich LifeSciences ranks #602 out of 1341 companies in the Biotechnology industry, placing it in the top 44.9%.
Is Greenwich LifeSciences' Piotroski F-Score too high?
Greenwich LifeSciences' current Piotroski F-Score of 3 is 50% above median its 10-year median of 2.00. Over the past 10 years, this metric has ranged from a low of 2.00 to a high of 5.00. The Biotechnology industry median Piotroski F-Score is 3.00. Greenwich LifeSciences' value of 3 is 0% at this industry median. Based on the distribution chart, Greenwich LifeSciences ranks #602 out of 1341 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Greenwich LifeSciences has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Greenwich LifeSciences' Piotroski F-Score compare to LRMR and RGNX?
According to the Biotechnology industry distribution chart, Greenwich LifeSciences ranks #602 out of 1341 companies for Piotroski F-Score. This puts Greenwich LifeSciences in the upper half of its industry. The industry median Piotroski F-Score is 3.00. Greenwich LifeSciences' value of 3 is 0% at this benchmark. Historically, Greenwich LifeSciences' own Piotroski F-Score has ranged from 2.00 to 5.00 over the past decade. While the company's 10-year median is 2.00 vs. the industry median of 3.00, Greenwich LifeSciences has consistently been at the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,341 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Greenwich LifeSciences's current Piotroski F-Score of 3 is 0% at the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Greenwich LifeSciences and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Greenwich LifeSciences's current Piotroski F-Score is 3, which is 50% above median its own 10-year median of 2.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Greenwich LifeSciences stock overvalued right now?
Greenwich LifeSciences (GLSI) has a current Piotroski F-Score of 3. The current Piotroski F-Score is 3, which is 50% above median its 10-year median of 2.00 and 0% at the Biotechnology industry median of 3.00. Greenwich LifeSciences' overall GF Score™ is 33/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Greenwich LifeSciences (GLSI), the current Piotroski F-Score is 3 as of Jun. 24, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Greenwich LifeSciences Business Description

Address 3992 Bluebonnet Drive, Building 14, Stafford, TX, USA, 77477
Greenwich LifeSciences Inc a clinical-stage biopharmaceutical company focused on its Phase III clinical trial, Flamingo-01, which is evaluating GLSI-100, an immunotherapy to prevent breast cancer recurrences. GP2 is a 9 amino acid transmembrane peptide of the HER2/neu protein, a cell surface receptor protein that is expressed in a variety of common cancers, including expression in 75 percent of breast cancers at low (1+), intermediate (2+), and high (3+ or over-expressor) levels. The combination of GP2 + GM-CSF is called GLSI-100. The company is currently expanding Flamingo-01 into Europe with plans to open up to 150 sites globally.
33GF Score

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Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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