Greenwich LifeSciencesGLSI -7.17%35 3-Year ROIIC % is -1,715.49 as of Dec. 2025. GuruFocus rates GLSI with a GF Score™ of 35/100. The stock has 1 warning sign investors should review. Among 1,324 Biotechnology companies, Greenwich LifeSciences ranks worse than 96.3% on this metric.
3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year.
Greenwich LifeSciences's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was -1,715.49%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for Greenwich LifeSciences's 3-Year ROIIC % or its related term are showing as below:
GLSI's 3-Year ROIIC % is ranked worse than 96.3% of 1324
companies
in the Biotechnology industry
Industry Median: -4.42
vs GLSI: -1715.49
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
Greenwich LifeSciences 3-Year ROIIC % Related Terms
Greenwich LifeSciences 3-Year ROIIC % Historical Data
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The historical data trend for Greenwich LifeSciences's 3-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
GLSI vs SABS, SRZN, ZNTL: 3-Year ROIIC % Comparison
For the Biotechnology subindustry, Greenwich LifeSciences's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Greenwich LifeSciences 3-Year ROIIC % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Greenwich LifeSciences's 3-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where Greenwich LifeSciences's 3-Year ROIIC % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
Greenwich LifeSciences (GLSI) has a 3-Year ROIIC % of -1,715.49 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Greenwich LifeSciences and its competitors. According to the industry distribution chart, Greenwich LifeSciences ranks #1275 out of 1324 companies in the Biotechnology industry, placing it in the top 96.3%.
Is Greenwich LifeSciences' 3-Year ROIIC % too high?
Greenwich LifeSciences' current 3-Year ROIIC % is -1,715.49. Based on the distribution chart, Greenwich LifeSciences ranks #1275 out of 1324 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Greenwich LifeSciences has a GF Score™ of 35/100, reflecting its overall financial health beyond just this single metric.
How does Greenwich LifeSciences' 3-Year ROIIC % compare to SABS and SRZN?
According to the Biotechnology industry distribution chart, Greenwich LifeSciences ranks #1275 out of 1324 companies for 3-Year ROIIC %. This places Greenwich LifeSciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Greenwich LifeSciences and its competitors. Greenwich LifeSciences's current 3-Year ROIIC % is -1,715.49. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Greenwich LifeSciences stock overvalued right now?
Greenwich LifeSciences (GLSI) has a current 3-Year ROIIC % of -1,715.49. The current 3-Year ROIIC % is -1,715.49. Greenwich LifeSciences' overall GF Score™ is 35/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Greenwich LifeSciences (GLSI), the current 3-Year ROIIC % is -1,715.49 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Greenwich LifeSciences Inc a clinical-stage biopharmaceutical company focused on its Phase III clinical trial, Flamingo-01, which is evaluating GLSI-100, an immunotherapy to prevent breast cancer recurrences. GP2 is a 9 amino acid transmembrane peptide of the HER2/neu protein, a cell surface receptor protein that is expressed in a variety of common cancers, including expression in 75 percent of breast cancers at low (1+), intermediate (2+), and high (3+ or over-expressor) levels. The combination of GP2 + GM-CSF is called GLSI-100. The company is currently expanding Flamingo-01 into Europe with plans to open up to 150 sites globally.
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