Regeneron Pharmaceuticals (STU:RGO) Piotroski F-Score: 5 (As of Jun. 29, 2026) — Near Median


STU:RGO Regeneron Pharmaceuticals Inc STU:RGO
87 GF Score
Price €554.60
GF Value €788.02
Valuation Significantly Undervalued
! 3 Warning Signs
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What is Regeneron Pharmaceuticals Piotroski F-Score?

Regeneron Pharmaceuticals STU:RGO +1.76% 87 Piotroski F-Score is 5 as of Jun. 29, 2026, which is at its 10-year median of 5.00. GuruFocus rates STU:RGO with a GF Score™ of 87/100 and a GF Value™ of €788.02 (Significantly Undervalued). The stock has 3 warning signs investors should review. Among 1,339 Biotechnology companies, Regeneron Pharmaceuticals ranks better than 85.06% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Regeneron Pharmaceuticals has an F-score of 5 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for Regeneron Pharmaceuticals's Piotroski F-Score or its related term are showing as below:

STU:RGO' s Piotroski F-Score Range Over the Past 10 Years
Min: 3   Med: 5   Max: 7
Current: 5

During the past 13 years, the highest Piotroski F-Score of Regeneron Pharmaceuticals was 7. The lowest was 3. And the median was 5.

Regeneron Pharmaceuticals  (STU:RGO) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Regeneron Pharmaceuticals Piotroski F-Score Related Terms


Regeneron Pharmaceuticals Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Regeneron Pharmaceuticals's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Regeneron Pharmaceuticals Piotroski F-Score Chart

Regeneron Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 5.00 5.00 6.00 5.00 5.00

Regeneron Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 5.00 5.00 5.00 5.00 5.00

STU:RGO vs ALNY, RVMD, ONC: Piotroski F-Score Comparison

For the Biotechnology subindustry, Regeneron Pharmaceuticals's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Regeneron Pharmaceuticals Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Regeneron Pharmaceuticals's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Regeneron Pharmaceuticals's Piotroski F-Score falls into.


STU:RGO
87GF Score
Regeneron Pharmaceuticals Inc STU:RGO
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Mar26) TTM:Last Year (Mar25) TTM:
Net Income was 1206.517 + 1243.92 + 721.288 + 629.028 = €3,801 Mil.
Cash Flow from Operations was 992.195 + 1379.132 + 999.778 + 933.248 = €4,304 Mil.
Revenue was 3186.745 + 3198.664 + 3317.192 + 3118.671 = €12,821 Mil.
Gross Profit was 2727.062 + 2754.26 + 2817.944 + 2539.64 = €10,839 Mil.
Average Total Assets from the begining of this year (Mar25)
to the end of this year (Mar26) was
(34729.31 + 33136.046 + 34224.329 + 34637.13 + 35351.512) / 5 = €34415.6654 Mil.
Total Assets at the begining of this year (Mar25) was €34,729 Mil.
Long-Term Debt & Capital Lease Obligation was €1,718 Mil.
Total Current Assets was €15,751 Mil.
Total Current Liabilities was €4,418 Mil.
Net Income was 1330.607 + 1207.881 + 876.404 + 748.047 = €4,163 Mil.

Revenue was 3295.256 + 3352.351 + 3618.686 + 2801.547 = €13,068 Mil.
Gross Profit was 2849.15 + 2909.87 + 3078.729 + 2372.07 = €11,210 Mil.
Average Total Assets from the begining of last year (Mar24)
to the end of last year (Mar25) was
(31620.032 + 33524.637 + 33735.152 + 36060.227 + 34729.31) / 5 = €33933.8716 Mil.
Total Assets at the begining of last year (Mar24) was €31,620 Mil.
Long-Term Debt & Capital Lease Obligation was €2,502 Mil.
Total Current Assets was €16,254 Mil.
Total Current Liabilities was €3,299 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Regeneron Pharmaceuticals's current Net Income (TTM) was 3,801. ==> Positive ==> Score 1.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Regeneron Pharmaceuticals's current Cash Flow from Operations (TTM) was 4,304. ==> Positive ==> Score 1.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Mar25)
=3800.753/34729.31
=0.10943935

ROA (Last Year)=Net Income/Total Assets (Mar24)
=4162.939/31620.032
=0.13165512

Regeneron Pharmaceuticals's return on assets of this year was 0.10943935. Regeneron Pharmaceuticals's return on assets of last year was 0.13165512. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Regeneron Pharmaceuticals's current Net Income (TTM) was 3,801. Regeneron Pharmaceuticals's current Cash Flow from Operations (TTM) was 4,304. ==> 4,304 > 3,801 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Mar26)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar25 to Mar26
=1718.063/34415.6654
=0.04992096

Gearing (Last Year: Mar25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar24 to Mar25
=2501.94/33933.8716
=0.07372987

Regeneron Pharmaceuticals's gearing of this year was 0.04992096. Regeneron Pharmaceuticals's gearing of last year was 0.07372987. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Mar26)=Total Current Assets/Total Current Liabilities
=15750.958/4418.16
=3.56504925

Current Ratio (Last Year: Mar25)=Total Current Assets/Total Current Liabilities
=16253.822/3299.105
=4.9267368

Regeneron Pharmaceuticals's current ratio of this year was 3.56504925. Regeneron Pharmaceuticals's current ratio of last year was 4.9267368. ==> Last year's current ratio is higher ==> Score 0.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Regeneron Pharmaceuticals's number of shares in issue this year was 107.7. Regeneron Pharmaceuticals's number of shares in issue last year was 111.2. ==> There is smaller number of shares in issue this year, or the same. ==> Score 1.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=10838.906/12821.272
=0.84538461

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=11209.819/13067.84
=0.85781728

Regeneron Pharmaceuticals's gross margin of this year was 0.84538461. Regeneron Pharmaceuticals's gross margin of last year was 0.85781728. ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Mar25)
=12821.272/34729.31
=0.36917727

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Mar24)
=13067.84/31620.032
=0.41327725

Regeneron Pharmaceuticals's asset turnover of this year was 0.36917727. Regeneron Pharmaceuticals's asset turnover of last year was 0.41327725. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=1+1+0+1+1+0+1+0+0
=5

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Regeneron Pharmaceuticals has an F-score of 5 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 5 mean?
Regeneron Pharmaceuticals (STU:RGO) has a Piotroski F-Score of 5 as of Jun. 29, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Regeneron Pharmaceuticals and its competitors. This is near median its historical median of 5.00. Over the past decade, Regeneron Pharmaceuticals' Piotroski F-Score has ranged from 3.00 to 7.00. According to the industry distribution chart, Regeneron Pharmaceuticals ranks #200 out of 1339 companies in the Biotechnology industry, placing it in the top 14.9%.
Is Regeneron Pharmaceuticals' Piotroski F-Score too high?
Regeneron Pharmaceuticals' current Piotroski F-Score of 5 is near median its 10-year median of 5.00. Over the past 10 years, this metric has ranged from a low of 3.00 to a high of 7.00. The Biotechnology industry median Piotroski F-Score is 3.00. Regeneron Pharmaceuticals' value of 5 is 66.7% above this industry median. Based on the distribution chart, Regeneron Pharmaceuticals ranks #200 out of 1339 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Regeneron Pharmaceuticals has a GF Score™ of 87/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Regeneron Pharmaceuticals' Piotroski F-Score compare to ALNY and RVMD?
According to the Biotechnology industry distribution chart, Regeneron Pharmaceuticals ranks #200 out of 1339 companies for Piotroski F-Score. This places Regeneron Pharmaceuticals in the top 15% of its industry — outperforming the majority of peers. The industry median Piotroski F-Score is 3.00. Regeneron Pharmaceuticals' value of 5 is 66.7% above this benchmark. Historically, Regeneron Pharmaceuticals' own Piotroski F-Score has ranged from 3.00 to 7.00 over the past decade. While the company's 10-year median is 5.00 vs. the industry median of 3.00, Regeneron Pharmaceuticals has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,339 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Regeneron Pharmaceuticals's current Piotroski F-Score of 5 is 66.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Regeneron Pharmaceuticals and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Regeneron Pharmaceuticals's current Piotroski F-Score is 5, which is near median its own 10-year median of 5.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Regeneron Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Regeneron Pharmaceuticals (STU:RGO) is currently considered Significantly Undervalued. The stock's GF Value™ is €788.02, compared to a current price of €554.60 — trading 29.6% below its estimated fair value. The current Piotroski F-Score is 5, which is near median its 10-year median of 5.00 and 66.7% above the Biotechnology industry median of 3.00. Regeneron Pharmaceuticals' overall GF Score™ is 87/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Regeneron Pharmaceuticals (STU:RGO), the current Piotroski F-Score is 5 as of Jun. 29, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Regeneron Pharmaceuticals (STU:RGO) Overvalued in 2026?

Based on GuruFocus' analysis, Regeneron Pharmaceuticals stock appears to be undervalued. The current stock price of €554.60 is trading 29.6% below its estimated GF Value™ of €788.02. GuruFocus considers Regeneron Pharmaceuticals to be Significantly Undervalued.

Key valuation signals for STU:RGO:

  • Piotroski F-Score: 5 (near median its 10-year median of 5.00)
  • GF Value™: €788.02 vs. price of €554.60 (29.6% below fair value)
  • GF Score™: 87/100 with 3 warning signs
  • Industry Position: 66.7% above the Biotechnology median (#200 of 1339)

No single metric tells the full story. See the STU:RGO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Regeneron Pharmaceuticals Business Description

Address 777 Old Saw Mill River Road, Tarrytown, NY, USA, 10591-6707
Regeneron Pharmaceuticals discovers, develops, and commercializes products that fight eye disease, cardiovascular disease, cancer, and inflammation. The company has several marketed products, including low-dose Eylea and Eylea HD, approved for wet age-related macular degeneration and other eye diseases; Dupixent in immunology; Praluent for LDL cholesterol lowering; Libtayo in oncology; Kevzara in rheumatoid arthritis; and Lynozyfic for multiple myeloma. Regeneron has multiple partnerships and collaboration agreements, with Sanofi (Dupixent, others) and Bayer (Eylea) as its largest partners.
87GF Score

Get the complete analysis for STU:RGO

Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€554.60
Price
€788.02
GF Value