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PeptiDreamTSE:4587 -2.81%75 Piotroski F-Score is 4 as of Aug. 18, 2026, which is 33% below its 10-year median of 6.00. GuruFocus rates TSE:4587 with a GF Score™ of 75/100 and a GF Value™ of 円776.12 (Modestly Overvalued). The stock has 2 warning signs investors should review. Among 1,328 Biotechnology companies, PeptiDream ranks better than 74.47% on this metric.
The zones of discrimination were as such:
Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3
PeptiDream has an F-score of 4 indicating the company's financial situation is typical for a stable company.
The historical rank and industry rank for PeptiDream's Piotroski F-Score or its related term are showing as below:
TSE:4587'
s Piotroski F-Score Range Over the Past 10 Years
Min: 2 Med: 6 Max: 9
Current: 4
During the past 13 years, the highest Piotroski F-Score of PeptiDream was 9. The lowest was 2. And the median was 6.
The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.
He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.
He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.
What he found was something that exceeded his most optimistic expectations.
Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.
Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).
Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.
PeptiDream Piotroski F-Score Related Terms
PeptiDream Piotroski F-Score Historical Data
* Premium members only.
The historical data trend for PeptiDream's Piotroski F-Score can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
TSE:4587 vs VRTX, REGN, RVMD: Piotroski F-Score Comparison
For the Biotechnology subindustry, PeptiDream's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
PeptiDream Piotroski F-Score vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, PeptiDream's Piotroski F-Score distribution charts can be found below:
* The bar in red indicates where PeptiDream's Piotroski F-Score falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
This Year (Jun26) TTM:
Last Year (Jun25) TTM:
Net Income was -1094.85 + -531.864 + -854.895 + 0 = 円-2,482 Mil. Cash Flow from Operations was -1591.822 + -732.486 + -945.684 + 0 = 円-3,270 Mil. Revenue was 4313.594 + 5663.852 + 4764.959 + 0 = 円14,742 Mil. Gross Profit was 1669.731 + 2687.04 + 2027.809 + 0 = 円6,385 Mil.
Average Total Assets from the begining of this year (Jun25)
to the end of this year (Jun26) was
(78537.623 + 77573.896 + 77033.185 + 74696.353 + 72225.925) / 5 = 円76013.3964 Mil. Total Assets at the begining of this year (Jun25) was 円78,538 Mil. Long-Term Debt & Capital Lease Obligation was 円13,076 Mil. Total Current Assets was 円33,073 Mil. Total Current Liabilities was 円7,973 Mil.
Net Income was -304.74 + -2605.64 + -1033.379 + -1089.111 = 円-5,033 Mil.
Revenue was 5470.709 + 5072.189 + 4233.246 + 4310.542 = 円19,087 Mil. Gross Profit was 2578.405 + 1964.558 + 1468.619 + 1696.96 = 円7,709 Mil.
Average Total Assets from the begining of last year (Jun24)
to the end of last year (Jun25) was
(95881.241 + 93430.552 + 92769.821 + 80734.989 + 78537.623) / 5 = 円88270.8452 Mil. Total Assets at the begining of last year (Jun24) was 円95,881 Mil. Long-Term Debt & Capital Lease Obligation was 円15,742 Mil. Total Current Assets was 円42,600 Mil. Total Current Liabilities was 円8,176 Mil.
*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.
Profitability
Question 1. Return on Assets (ROA)
Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.
Score 1 if positive, 0 if negative.
PeptiDream's current Net Income (TTM) was -2,482.
==> Negative ==> Score 0.
Question 2. Cash Flow Return on Assets (CFROA)
Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.
PeptiDream's return on assets of this year was -0.03159771. PeptiDream's return on assets of last year was -0.05249066.
==> This year is higher. ==> Score 1.
Question 4. Quality of Earnings (Accrual)
Compare Cash flow return on assets (2) to return on assets (1)
PeptiDream's gearing of this year was 0.17202561. PeptiDream's gearing of last year was 0.17834229.
==> This year is lower or equal to last year. ==> Score 1.
Question 6. Change in Working Capital (Liquidity)
Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.
Score 1 if this year's current ratio is higher, 0 if it's lower
PeptiDream's current ratio of this year was 4.14798976. PeptiDream's current ratio of last year was 5.21038865.
==> Last year's current ratio is higher ==> Score 0.
Question 7. Change in Shares in Issue
Compare the number of shares in issue this year, to the number in issue last year.
Score 0 if there is larger number of shares in issue this year, 1 otherwise.
PeptiDream's number of shares in issue this year was 128.874. PeptiDream's number of shares in issue last year was 129.399.
==> There is smaller number of shares in issue this year, or the same. ==> Score 1.
Efficiency
Question 8. Change in Gross Margin
Compare this year's gross margin (Gross Profit divided by sales) to last year's.
Score 1 if this year's gross margin is higher, 0 if it's lower.
PeptiDream's gross margin of this year was 0.43307588. PeptiDream's gross margin of last year was 0.40387011.
==> This year's gross margin is higher. ==> Score 1.
Question 9. Change in asset turnover
Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.
Score 1 if this year's asset turnover ratio is higher, 0 if it's lower
PeptiDream's asset turnover of this year was 0.18771137. PeptiDream's asset turnover of last year was 0.1990659.
==> Last year's asset turnover is higher ==> Score 0.
Evaluation
Piotroski F-Score
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Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3
PeptiDream has an F-score of 4 indicating the company's financial situation is typical for a stable company.
PeptiDream (TSE:4587) has a Piotroski F-Score of 4 as of Aug. 18, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on PeptiDream and its competitors. This is 33% below median its historical median of 6.00. Over the past decade, PeptiDream's Piotroski F-Score has ranged from 2.00 to 9.00. According to the industry distribution chart, PeptiDream ranks #339 out of 1328 companies in the Biotechnology industry, placing it in the top 25.5%.
Is PeptiDream's Piotroski F-Score too high?
PeptiDream's current Piotroski F-Score of 4 is 33% below median its 10-year median of 6.00. Over the past 10 years, this metric has ranged from a low of 2.00 to a high of 9.00. The Biotechnology industry median Piotroski F-Score is 3.00. PeptiDream's value of 4 is 33.3% above this industry median. Based on the distribution chart, PeptiDream ranks #339 out of 1328 companies in the Biotechnology industry, which is above the industry midpoint. Overall, PeptiDream has a GF Score™ of 75/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does PeptiDream's Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, PeptiDream ranks #339 out of 1328 companies for Piotroski F-Score. This puts PeptiDream in the upper half of its industry. The industry median Piotroski F-Score is 3.00. PeptiDream's value of 4 is 33.3% above this benchmark. Historically, PeptiDream's own Piotroski F-Score has ranged from 2.00 to 9.00 over the past decade. While the company's 10-year median is 6.00 vs. the industry median of 3.00, PeptiDream has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,328 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. PeptiDream's current Piotroski F-Score of 4 is 33.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on PeptiDream and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. PeptiDream's current Piotroski F-Score is 4, which is 33% below median its own 10-year median of 6.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PeptiDream stock overvalued right now?
Based on GuruFocus' analysis, PeptiDream (TSE:4587) is currently considered Modestly Overvalued. The stock's GF Value™ is 円776.12, compared to a current price of 円1,002.50 — trading 29.2% above its estimated fair value. The current Piotroski F-Score is 4, which is 33% below median its 10-year median of 6.00 and 33.3% above the Biotechnology industry median of 3.00. PeptiDream's overall GF Score™ is 75/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For PeptiDream (TSE:4587), the current Piotroski F-Score is 4 as of Aug. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is PeptiDream (TSE:4587) Overvalued in 2026?
Based on GuruFocus' analysis, PeptiDream stock appears to be overvalued.
The current stock price of 円1,002.50 is trading 29.2% above its estimated GF Value™ of 円776.12.
GuruFocus considers PeptiDream to be Modestly Overvalued.
Key valuation signals for TSE:4587:
Piotroski F-Score: 4 (33% below median its 10-year median of 6.00)
GF Value™: 円776.12 vs. price of 円1,002.50 (29.2% above fair value)
Industry Position: 33.3% above the Biotechnology median (#339 of 1328)
No single metric tells the full story. See the TSE:4587 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
PeptiDream Inc is engaged in the drug discovery and development business. The group utilizes PDPS, its proprietary drug discovery and development platform system, for drug discovery and development, and it conducts radiopharmaceutical business through a wholly owned subsidiary and is involved in the research, development, and manufacturing of pharmaceuticals, etc. Its reportable segments are Drug discovery and development business and Radiopharmaceutical business.
75GF Score
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