PeptiDream (TSE:4587) E10: 円29.29 (As of Mar. 2026)


TSE:4587 PeptiDream Inc TSE:4587
72 GF Score
Price 円1,025.50
GF Value 円1,585.83
Valuation Possible Value Trap
! 4 Warning Signs
View Full Analysis

What is PeptiDream E10?

PeptiDream TSE:4587 +2.83% 72 E10 is 円29.29 as of Mar. 2026. GuruFocus rates TSE:4587 with a GF Score™ of 72/100 and a GF Value™ of 円1,585.83 (Possible Value Trap). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

PeptiDream's adjusted earnings per share data for the three months ended in Mar. 2026 was 円-6.620. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円29.29 for the trailing ten years ended in Mar. 2026.

During the past 12 months, PeptiDream's average E10 Growth Rate was -12.20% per year. During the past 3 years, the average E10 Growth Rate was 17.00% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of PeptiDream was 17.00% per year. The lowest was 17.00% per year. And the median was 17.00% per year.

As of today (2026-06-28), PeptiDream's current stock price is 円1025.50. PeptiDream's E10 for the quarter that ended in Mar. 2026 was 円29.29. PeptiDream's Shiller PE Ratio of today is 35.01.

During the past 13 years, the highest Shiller PE Ratio of PeptiDream was 127.05. The lowest was 31.84. And the median was 64.74.


PeptiDream  (TSE:4587) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

PeptiDream's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=1025.50/29.29
=35.01

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of PeptiDream was 127.05. The lowest was 31.84. And the median was 64.74.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


PeptiDream E10 Related Terms


PeptiDream E10 Historical Data

* Premium members only.

The historical data trend for PeptiDream's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PeptiDream E10 Chart

PeptiDream Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 19.18 21.40 33.98 30.69

PeptiDream Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 33.35 31.81 31.01 30.69 29.29

TSE:4587 vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, PeptiDream's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PeptiDream Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PeptiDream's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where PeptiDream's Shiller PE Ratio falls into.


TSE:4587
72GF Score
PeptiDream Inc TSE:4587
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

PeptiDream E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, PeptiDream's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-6.62/112.7000*112.7000
=-6.620

Current CPI (Mar. 2026) = 112.7000.

PeptiDream Quarterly Data

per share eps CPI Adj_EPS
201606 4.670 98.100 5.365
201609 2.150 98.000 2.473
201612 0.550 98.400 0.630
201703 -1.630 98.100 -1.873
201706 13.290 98.500 15.206
201709 -5.510 98.800 -6.285
201712 0.962 99.400 1.091
201803 -2.440 99.200 -2.772
201806 25.835 99.200 29.351
201809 0.250 99.900 0.282
201812 4.380 99.700 4.951
201903 0.660 99.700 0.746
201906 16.040 99.800 18.113
201909 -1.480 100.100 -1.666
201912 -2.420 100.500 -2.714
202003 -2.710 100.300 -3.045
202006 9.788 99.900 11.042
202009 -1.510 99.900 -1.703
202012 28.860 99.300 32.755
202103 -1.740 99.900 -1.963
202106 -1.750 99.500 -1.982
202109 19.120 100.100 21.527
202112 0.710 100.100 0.799
202203 -6.390 101.100 -7.123
202206 -2.330 101.800 -2.579
202209 7.280 103.100 7.958
202212 59.580 104.100 64.502
202303 -1.920 104.400 -2.073
202306 -3.700 105.200 -3.964
202309 32.910 106.200 34.924
202312 -3.890 106.800 -4.105
202403 -6.500 107.200 -6.833
202406 144.600 108.200 150.614
202409 -2.350 108.900 -2.432
202412 -20.080 110.700 -20.443
202503 -7.970 111.100 -8.085
202506 -8.430 111.700 -8.505
202509 -8.480 112.000 -8.533
202512 -4.110 113.000 -4.099
202603 -6.620 112.700 -6.620

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円29.29 mean?
PeptiDream (TSE:4587) has a E10 of 円29.29 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on PeptiDream and its competitors.
Is PeptiDream's E10 too high?
PeptiDream's current E10 is 円29.29. Overall, PeptiDream has a GF Score™ of 72/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does PeptiDream's E10 compare to VRTX and REGN?
PeptiDream's E10 of 円29.29 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on PeptiDream and its competitors. PeptiDream's current E10 is 円29.29. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PeptiDream stock overvalued right now?
Based on GuruFocus' analysis, PeptiDream (TSE:4587) is currently considered Possible Value Trap. The stock's GF Value™ is 円1,585.83, compared to a current price of 円1,025.50 — trading 35.3% below its estimated fair value. The current E10 is 円29.29. PeptiDream's overall GF Score™ is 72/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For PeptiDream (TSE:4587), the current E10 is 円29.29 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is PeptiDream (TSE:4587) Overvalued in 2026?

Based on GuruFocus' analysis, PeptiDream stock appears to be undervalued. The current stock price of 円1,025.50 is trading 35.3% below its estimated GF Value™ of 円1,585.83. GuruFocus considers PeptiDream to be Possible Value Trap.

Key valuation signals for TSE:4587:

  • E10: 円29.29
  • GF Value™: 円1,585.83 vs. price of 円1,025.50 (35.3% below fair value)
  • GF Score™: 72/100 with 4 warning signs

No single metric tells the full story. See the TSE:4587 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


PeptiDream Business Description

Other Exchanges PPTDF:USA
Address 3-25-23 Tonomachi, Kawasaki-ku, Kanagawa Prefecture, Kawasaki, JPN, 210-0821
PeptiDream Inc is engaged in the drug discovery and development business. The group utilizes PDPS, its proprietary drug discovery and development platform system, for drug discovery and development, and it conducts radiopharmaceutical business through a wholly owned subsidiary and is involved in the research, development, and manufacturing of pharmaceuticals, etc. Its reportable segments are Drug discovery and development business and Radiopharmaceutical business.
72GF Score

Get the complete analysis for TSE:4587

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円1,025.50
Price
円1,585.83
GF Value