ONC (BeOne Medicines) Graham Number: $97.57 (As of Mar. 2026) — 1658% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ONC BeOne Medicines Ltd ONC
77 GF Score
Price $326.77
GF Value $370.48
Valuation Modestly Undervalued
! 4 Warning Signs
View Full Analysis

What is BeOne Medicines Graham Number?

BeOne Medicines ONC +2.14% 77 Graham Number is $97.57 as of Mar. 2026, which is 1658% above its 10-year median of 5.55. GuruFocus rates ONC with a GF Score™ of 77/100 and a GF Value™ of $370.48 (Modestly Undervalued). The stock has 4 warning signs investors should review. Among 252 Biotechnology companies, BeOne Medicines ranks worse than 73.41% on this metric.

Graham Number is a figure that measures a stock's fundamental value by taking into account the company's earnings per share and book value per share. The Graham number is the upper bound of the price range that a defensive investor should pay for the stock. According to the theory, any stock price below the Graham number is considered undervalued, and thus worth investing in.

As of today (2026-07-23), the stock price of BeOne Medicines is $326.77. BeOne Medicines's graham number for the quarter that ended in Mar. 2026 was $97.57. Therefore, BeOne Medicines's Price to Graham Number ratio for today is 3.35.

The historical rank and industry rank for BeOne Medicines's Graham Number or its related term are showing as below:

ONC' s Price-to-Graham-Number Range Over the Past 10 Years
Min: 3.04   Med: 5.55   Max: 14.07
Current: 3.35

During the past 13 years, the highest Price to Graham Number ratio of BeOne Medicines was 14.07. The lowest was 3.04. And the median was 5.55.

ONC's Price-to-Graham-Number is ranked worse than
73.41% of 252 companies
in the Biotechnology industry
Industry Median: 1.745 vs ONC: 3.35

Graham Number is a combination of asset valuation and earnings power valuation. It is a very conservative way of valuing a stock.


BeOne Medicines  (NAS:ONC) Graham Number Explanation

Ben Graham actually did not publish a formula like this. But he wrote in The Intelligent Investor (1948 version) regarding to the criteria for purchases:

Current price should not be more than 15 times average earnings of the past three years.

Current price should not be more than 1.5 times the book value last reported. However, a multiplier of earnings below 15 could justify a correspondingly higher multiplier of assets. As a rule of thumb we suggest that the product of the multiplier times the ratio of price to book value should not exceed 22.5. (This figure corresponds to 15 times earnings and 1.5 times book value. It would admit an issue selling at only 9 times earnings and 2.5 times asset value, etc.)

Unlike valuation methods such as DCF or Discounted Earnings, the Graham number does not take growth into the valuation. Unlike the valuation methods based on book value alone, it takes into account the earnings power. Therefore, the Graham Number is a combination of asset valuation and earnings power valuation.

In general, the Graham number is a very conservative way of valuing a stock. It cannot be applied to companies with negative book values.

BeOne Medicines's Price to Graham number Ratio for today is calculated as

Price to Graham number=Share Price (Today)/Graham number (Q: Mar. 2026 )
=326.77/97.57
=3.35

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Please keep these in mind:

1. Graham Number does not take growth into account. Therefore it underestimates the values of the companies that have good earnings growth. We feel that if the earnings per share grows more than 10% a year, Graham Number underestimates the value.
2. Graham Number punishes the companies that have temporarily low earnings. Therefore, an average of earnings makes more sense in the calculation of Graham Number.
3. Graham Numbers underestimates companies that are light with book.


BeOne Medicines Graham Number Related Terms


BeOne Medicines Graham Number Historical Data

* Premium members only.

The historical data trend for BeOne Medicines's Graham Number can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

BeOne Medicines Graham Number Chart

BeOne Medicines Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Graham Number
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 83.08

BeOne Medicines Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Graham Number Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 19.34 43.31 61.34 82.41 97.57

ONC vs MRNA, RPRX, ROIV: Graham Number Comparison

For the Biotechnology subindustry, BeOne Medicines's Price-to-Graham-Number, along with its competitors' market caps and Price-to-Graham-Number data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


BeOne Medicines Price-to-Graham-Number vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, BeOne Medicines's Price-to-Graham-Number distribution charts can be found below:

* The bar in red indicates where BeOne Medicines's Price-to-Graham-Number falls into.


ONC
77GF Score
BeOne Medicines Ltd ONC
Graham Number is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

BeOne Medicines Graham Number Calculation

Graham Number is a concept based on Ben Graham's conservative valuation of companies.

BeOne Medicines's Graham Number for the fiscal year that ended in Dec. 2025 is calculated as

Graham Number
=sqrt of (22.5* Tangible Book per Share *EPS without NRI)
=sqrt of (22.5*38.065*8.06)
=83.08

BeOne Medicines's Graham Number for the quarter that ended in Mar. 2026 is calculated as

Graham Number
=sqrt of (22.5*Tangible Book per Share*EPS without NRI (TTM))
=sqrt of (22.5*42.27*10.01)
=97.57

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Graham Number →
What does a Graham Number of $97.57 mean?
BeOne Medicines (ONC) has a Graham Number of $97.57 as of Mar. 2026. The Graham Number values a company based on its per-share earnings and book value. View historical data on BeOne Medicines and its competitors. This is 1658% above median its historical median of 5.55. Over the past decade, BeOne Medicines' Graham Number has ranged from 3.04 to 14.07. According to the industry distribution chart, BeOne Medicines ranks #185 out of 252 companies in the Biotechnology industry, placing it in the top 73.4%.
Is BeOne Medicines' Graham Number too high?
BeOne Medicines' current Graham Number of $97.57 is 1658% above median its 10-year median of 5.55. Over the past 10 years, this metric has ranged from a low of 3.04 to a high of 14.07. The Biotechnology industry median Graham Number is 1.75. BeOne Medicines' value of $97.57 is 5491.4% above this industry median. Based on the distribution chart, BeOne Medicines ranks #185 out of 252 companies in the Biotechnology industry, which is below the industry midpoint. Overall, BeOne Medicines has a GF Score™ of 77/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does BeOne Medicines' Graham Number compare to MRNA and RPRX?
According to the Biotechnology industry distribution chart, BeOne Medicines ranks #185 out of 252 companies for Graham Number. This places BeOne Medicines in the lower half of its industry. The industry median Graham Number is 1.75. BeOne Medicines' value of $97.57 is 5491.4% above this benchmark. Historically, BeOne Medicines' own Graham Number has ranged from 3.04 to 14.07 over the past decade. While the company's 10-year median is 5.55 vs. the industry median of 1.75, BeOne Medicines has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Graham Number for a Biotechnology company?
The median Graham Number among Biotechnology companies is 1.75, based on 252 companies in the industry. Companies in the top quartile (top 25%) have a Graham Number significantly above this median, while those in the bottom quartile fall well below. However, Graham Number should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. BeOne Medicines's current Graham Number of $97.57 is 5491.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Graham Number mean?
A high Graham Number can signal that a stock is expensive relative to its fundamentals. The Graham Number values a company based on its per-share earnings and book value. View historical data on BeOne Medicines and its competitors. For the Biotechnology industry, the median Graham Number is 1.75 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. BeOne Medicines's current Graham Number is $97.57, which is 1658% above median its own 10-year median of 5.55. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BeOne Medicines stock overvalued right now?
Based on GuruFocus' analysis, BeOne Medicines (ONC) is currently considered Modestly Undervalued. The stock's GF Value™ is $370.48, compared to a current price of $326.77 — trading 11.8% below its estimated fair value. The current Graham Number is $97.57, which is 1658% above median its 10-year median of 5.55 and 5491.4% above the Biotechnology industry median of 1.75. BeOne Medicines' overall GF Score™ is 77/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Graham Number calculated?
Graham Number is calculated from a company's financial statements. For BeOne Medicines (ONC), the current Graham Number is $97.57 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is BeOne Medicines (ONC) Overvalued in 2026?

Based on GuruFocus' analysis, BeOne Medicines stock appears to be undervalued. The current stock price of $326.77 is trading 11.8% below its estimated GF Value™ of $370.48. GuruFocus considers BeOne Medicines to be Modestly Undervalued.

Key valuation signals for ONC:

  • Graham Number: $97.57 (1658% above median its 10-year median of 5.55)
  • GF Value™: $370.48 vs. price of $326.77 (11.8% below fair value)
  • GF Score™: 77/100 with 4 warning signs
  • Industry Position: 5491.4% above the Biotechnology median (#185 of 252)

No single metric tells the full story. See the ONC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


BeOne Medicines Business Description

Address c/o BeOne Medicines I GmbH, 94 Aeschengraben 27, 21st Floor, Basel, CHE, 4051
Formerly known as BeiGene and founded in 2010 in Beijing, BeOne is a commercial-stage biotech firm that produces oncology therapeutics. The company's main product is Brukinsa, which is a small-molecule drug that treats multiple forms of Non-Hodgkin lymphoma and leukemia. The company conducts drug discovery, runs global clinical trials, and manufactures drugs independently. As of 2025, Brukinsa made up for 74% of total revenue, while it has two other approved commercialized drugs in its portfolio, Beqalzi and Tevimbra. While Brukinsa has a global leadership, the other two drugs generate revenue mostly from China. Based on Brukinsa, BeOne competes with AbbVie and AstraZeneca mainly. The company also has more than 50 drugs in clinical trials in its active pipeline, focused on other cancers.
77GF Score

Get the complete analysis for ONC

Graham Number is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$326.77
Price
$370.48
GF Value