SIGY (Sigyn Therapeutics) Gross Margin %: 0.00% (As of Sep. 2025)


What is Sigyn Therapeutics Gross Margin %?

Sigyn Therapeutics SIGY +22.62% Gross Margin % is 0.00% as of Sep. 2025. The stock has 3 warning signs investors should review. Among 732 Biotechnology companies, Sigyn Therapeutics ranks worse than 136611.89% on this metric.

Gross Margin % is calculated as gross profit divided by its revenue. Sigyn Therapeutics's Gross Profit for the three months ended in Sep. 2025 was $0.00 Mil. Sigyn Therapeutics's Revenue for the three months ended in Sep. 2025 was $0.00 Mil. Therefore, Sigyn Therapeutics's Gross Margin % for the quarter that ended in Sep. 2025 was 0.00%. If there's no value for Cost of Goods Sold, then Gross Margin % is not calculated.


The historical rank and industry rank for Sigyn Therapeutics's Gross Margin % or its related term are showing as below:


During the past 11 years, the highest Gross Margin % of Sigyn Therapeutics was 75.52%. The lowest was 44.74%. And the median was 62.00%.

SIGY's Gross Margin % is not ranked *
in the Biotechnology industry.
Industry Median: 60.91
* Ranked among companies with meaningful Gross Margin % only.

Sigyn Therapeutics had a gross margin of N/A% for the quarter that ended in Sep. 2025 => No sustainable competitive advantage

The 5-Year average Growth Rate of Gross Margin for Sigyn Therapeutics was 0.00% per year.


Sigyn Therapeutics  (OTCPK:SIGY) Gross Margin % Explanation

Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.

Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %

1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key

Sigyn Therapeutics had a gross margin of N/A% for the quarter that ended in Sep. 2025 => No sustainable competitive advantage


Be Aware

If a company loses its competitive advantages, usually its gross margin declines well before its sales declines. Watching Gross Margin % and Operating Margin % closely helps avoid value trap situations.


Sigyn Therapeutics Gross Margin % Related Terms


Sigyn Therapeutics Gross Margin % Historical Data

* Premium members only.

The historical data trend for Sigyn Therapeutics's Gross Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sigyn Therapeutics Gross Margin % Chart

Sigyn Therapeutics Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Gross Margin %
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Sigyn Therapeutics Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25
Gross Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

SIGY vs RGBP, ENDV, VRTX: Gross Margin % Comparison

For the Biotechnology subindustry, Sigyn Therapeutics's Gross Margin %, along with its competitors' market caps and Gross Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Sigyn Therapeutics Gross Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Sigyn Therapeutics's Gross Margin % distribution charts can be found below:

* The bar in red indicates where Sigyn Therapeutics's Gross Margin % falls into.



Sigyn Therapeutics Gross Margin % Calculation

Gross Margin is the percentage of Gross Profit out of sales or Revenue. (Note that if there's no value for Cost of Goods Sold, then Gross Margin % is not calculated.)

Sigyn Therapeutics's Gross Margin for the fiscal year that ended in Dec. 2024 is calculated as

Gross Margin % (A: Dec. 2024 )=Gross Profit (A: Dec. 2024 ) / Revenue (A: Dec. 2024 )
=0 / 0
=(Revenue - Cost of Goods Sold) / Revenue
=(0 - 0) / 0
=N/A %

Sigyn Therapeutics's Gross Margin for the quarter that ended in Sep. 2025 is calculated as


Gross Margin % (Q: Sep. 2025 )=Gross Profit (Q: Sep. 2025 ) / Revenue (Q: Sep. 2025 )
=0 / 0
=(Revenue - Cost of Goods Sold) / Revenue
=(0 - 0) / 0
=N/A %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.

Frequently Asked Questions Learn more about Gross Margin % →
What does a Gross Margin % of 0.00% mean?
Sigyn Therapeutics (SIGY) has a Gross Margin % of 0.00% as of Sep. 2025. Gross margin is the ratio of total gross profit to net sales. View historical data on Sigyn Therapeutics and its competitors. Over the past decade, Sigyn Therapeutics' Gross Margin % has ranged from 44.74 to 75.52. According to the industry distribution chart, Sigyn Therapeutics ranks #999999 out of 732 companies in the Biotechnology industry.
Is Sigyn Therapeutics' Gross Margin % too high?
Sigyn Therapeutics' current Gross Margin % is 0.00%. Over the past 10 years, this metric has ranged from a low of 44.74 to a high of 75.52. Based on the distribution chart, Sigyn Therapeutics ranks #999999 out of 732 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does Sigyn Therapeutics' Gross Margin % compare to RGBP and ENDV?
According to the Biotechnology industry distribution chart, Sigyn Therapeutics ranks #999999 out of 732 companies for Gross Margin %. This places Sigyn Therapeutics in the lower half of its industry. The industry median Gross Margin % is 60.91. Historically, Sigyn Therapeutics' own Gross Margin % has ranged from 44.74 to 75.52 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Margin % for a Biotechnology company?
The median Gross Margin % among Biotechnology companies is 60.91, based on 732 companies in the industry. Companies in the top quartile (top 25%) have a Gross Margin % significantly above this median, while those in the bottom quartile fall well below. However, Gross Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Margin % mean?
A high Gross Margin % can signal that a stock is expensive relative to its fundamentals. Gross margin is the ratio of total gross profit to net sales. View historical data on Sigyn Therapeutics and its competitors. For the Biotechnology industry, the median Gross Margin % is 60.91 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Sigyn Therapeutics's current Gross Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sigyn Therapeutics stock overvalued right now?
Sigyn Therapeutics (SIGY) has a current Gross Margin % of 0.00%. The current Gross Margin % is 0.00%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Margin % calculated?
Gross Margin % is calculated from a company's financial statements. For Sigyn Therapeutics (SIGY), the current Gross Margin % is 0.00% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Sigyn Therapeutics Business Description

Address 2468 Historic Decatur Road, Suite 140, San Diego, CA, USA, 92106
Sigyn Therapeutics Inc is a development-stage therapeutic technology company. Its business focus is the clinical advancement of Sigyn Therapy, a multi-function blood purification technology designed to overcome the limitations of previous drugs and devices to treat life-threatening inflammatory disorders, including sepsis, the cause of hospital deaths world-wide. To support widespread implementation, the company designed Sigyn Therapy to be a single-use disposable device that is deployable on the world-wide infrastructure of hemodialysis and continuous renal replacement therapy machines already located in hospitals and clinics.