HOWL (Werewolf Therapeutics) Moat Score: 3/10 (As of Aug. 10, 2026)

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HOWL Werewolf Therapeutics Inc HOWL
32 GF Score
Price $0.38
GF Value $3.78
Valuation Possible Value Trap
! 2 Warning Signs
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What is Werewolf Therapeutics Moat Score?

Werewolf Therapeutics HOWL -4.02% 32 Moat Score is 3 as of Aug. 10, 2026. GuruFocus rates HOWL with a GF Score™ of 32/100 and a GF Value™ of $3.78 (Possible Value Trap). The stock has 2 warning signs investors should review. Among 1,388 Biotechnology companies, Werewolf Therapeutics ranks better than 75.5% on this metric.

Werewolf Therapeutics has the Moat Score of 3, which implies that the company might have No Moat - Very weak/transient advantages.

Werewolf Therapeutics has No Moat: Werewolf Therapeutics Inc has weak competitive advantages with limited intellectual property and no significant market leadership. The biotech sector's high competition and low switching costs further weaken its position.

Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more.

The company's Moat Score is based on these criteria:

1. Market leadership and sustainable market share
2. Network effects and significant customer switching costs
3. Valuable intellectual property and patents
4. Strong brand strength and deep customer loyalty
5. Durable cost advantages (e.g., economies of scale, proprietary technology)
6. Significant regulatory barriers and exclusive licenses
7. Superior distribution network
8. Strong and sustainable pricing power
9. Consistent and impactful innovation and R&D capabilities

Based on the research, GuruFocus believes Werewolf Therapeutics might have No Moat - Very weak/transient advantages.

Werewolf Therapeutics  (NAS:HOWL) Moat Score Explanation

The Moat Score ranges from 0 to 10, with 10 as the highest. GuruFocus divided Moat Score into following 8 categories:

Moat Score Moat Level
10Wide Moat - Exceptionally dominant and durable wide moat
8 - 9Wide Moat - Clear and robust wide moat
7Wide Moat - Entry-level wide moat, clearly possessing durable advantages
6Narrow Moat - Strong narrow moat, clearly distinguishable but not wide
5Narrow Moat - Solid narrow moat
4Narrow Moat - Discernible but modest moat
1 - 3No Moat - Very weak/transient advantages
0No Moat - No discernible moat

Werewolf Therapeutics Moat Score Related Terms

HOWL vs CVM, MRKR, ZIVO: Moat Score Comparison

For the Biotechnology subindustry, Werewolf Therapeutics's Moat Score, along with its competitors' market caps and Moat Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Werewolf Therapeutics Moat Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Werewolf Therapeutics's Moat Score distribution charts can be found below:

* The bar in red indicates where Werewolf Therapeutics's Moat Score falls into.


HOWL
32GF Score
Werewolf Therapeutics Inc HOWL
Moat Score is just one metric. See GF Score™, valuation, warning signs, and more.
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Frequently Asked Questions Learn more about Moat Score →
What does a Moat Score of 3 mean?
Werewolf Therapeutics (HOWL) has a Moat Score of 3 as of Aug. 10, 2026. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. According to the industry distribution chart, Werewolf Therapeutics ranks #340 out of 1388 companies in the Biotechnology industry, placing it in the top 24.5%.
Is Werewolf Therapeutics' Moat Score too high?
Werewolf Therapeutics' current Moat Score is 3. The Biotechnology industry median Moat Score is 2.00. Werewolf Therapeutics' value of 3 is 50% above this industry median. Based on the distribution chart, Werewolf Therapeutics ranks #340 out of 1388 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Werewolf Therapeutics has a GF Score™ of 32/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Werewolf Therapeutics' Moat Score compare to CVM and MRKR?
According to the Biotechnology industry distribution chart, Werewolf Therapeutics ranks #340 out of 1388 companies for Moat Score. This places Werewolf Therapeutics in the top 25% of its industry — outperforming the majority of peers. The industry median Moat Score is 2.00. Werewolf Therapeutics' value of 3 is 50% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Moat Score for a Biotechnology company?
The median Moat Score among Biotechnology companies is 2.00, based on 1,388 companies in the industry. Companies in the top quartile (top 25%) have a Moat Score significantly above this median, while those in the bottom quartile fall well below. However, Moat Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Werewolf Therapeutics's current Moat Score of 3 is 50% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Moat Score mean?
A high Moat Score can signal that a stock is expensive relative to its fundamentals. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. For the Biotechnology industry, the median Moat Score is 2.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Werewolf Therapeutics's current Moat Score is 3. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Werewolf Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Werewolf Therapeutics (HOWL) is currently considered Possible Value Trap. The stock's GF Value™ is $3.78, compared to a current price of $0.38 — trading 89.9% below its estimated fair value. The current Moat Score is 3 and 50% above the Biotechnology industry median of 2.00. Werewolf Therapeutics' overall GF Score™ is 32/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Moat Score calculated?
Moat Score is calculated from a company's financial statements. For Werewolf Therapeutics (HOWL), the current Moat Score is 3 as of Aug. 10, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Werewolf Therapeutics (HOWL) Overvalued in 2026?

Based on GuruFocus' analysis, Werewolf Therapeutics stock appears to be undervalued. The current stock price of $0.38 is trading 89.9% below its estimated GF Value™ of $3.78. GuruFocus considers Werewolf Therapeutics to be Possible Value Trap.

Key valuation signals for HOWL:

  • Moat Score: 3
  • GF Value™: $3.78 vs. price of $0.38 (89.9% below fair value)
  • GF Score™: 32/100 with 2 warning signs
  • Industry Position: 50% above the Biotechnology median (#340 of 1388)

No single metric tells the full story. See the HOWL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Werewolf Therapeutics Business Description

Address 200 Talcott Avenue, 2nd Floor, Watertown, MA, USA, 02472
Werewolf Therapeutics Inc is a biopharmaceutical company pioneering the development of therapeutics engineered to stimulate the body's immune system for the treatment of cancer and other immune-mediated conditions. It is leveraging the proprietary PREDATOR platform to design conditionally activated molecules that stimulate both adaptive and innate immunity with the goal of addressing the limitations of conventional proinflammatory immune therapies. It has one reportable segment, which focuses on the discovery and development of cancer therapeutics.
32GF Score

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Moat Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.38
Price
$3.78
GF Value