PEPG (PepGen) Moat Score: 3/10 (As of Jul. 08, 2026)


PEPG PepGen Inc PEPG
32 GF Score
Price $2.05
! 2 Warning Signs
View Full Analysis

What is PepGen Moat Score?

PepGen PEPG -0.49% 32 Moat Score is 3 as of Jul. 08, 2026. GuruFocus rates PEPG with a GF Score™ of 32/100. The stock has 2 warning signs investors should review. Among 1,393 Biotechnology companies, PepGen ranks better than 75.52% on this metric.

PepGen has the Moat Score of 3, which implies that the company might have No Moat - Very weak/transient advantages.

PepGen has No Moat: PepGen Inc operates in the biotech sector with limited market share and lacks significant intellectual property or patents that provide a durable advantage. The company faces intense competition and does not have strong brand recognition or customer loyalty, resulting in a very weak moat.

Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more.

The company's Moat Score is based on these criteria:

1. Market leadership and sustainable market share
2. Network effects and significant customer switching costs
3. Valuable intellectual property and patents
4. Strong brand strength and deep customer loyalty
5. Durable cost advantages (e.g., economies of scale, proprietary technology)
6. Significant regulatory barriers and exclusive licenses
7. Superior distribution network
8. Strong and sustainable pricing power
9. Consistent and impactful innovation and R&D capabilities

Based on the research, GuruFocus believes PepGen might have No Moat - Very weak/transient advantages.

PepGen  (NAS:PEPG) Moat Score Explanation

The Moat Score ranges from 0 to 10, with 10 as the highest. GuruFocus divided Moat Score into following 8 categories:

Moat Score Moat Level
10Wide Moat - Exceptionally dominant and durable wide moat
8 - 9Wide Moat - Clear and robust wide moat
7Wide Moat - Entry-level wide moat, clearly possessing durable advantages
6Narrow Moat - Strong narrow moat, clearly distinguishable but not wide
5Narrow Moat - Solid narrow moat
4Narrow Moat - Discernible but modest moat
1 - 3No Moat - Very weak/transient advantages
0No Moat - No discernible moat

PepGen Moat Score Related Terms

PEPG vs ENGN, NTHI, GUTS: Moat Score Comparison

For the Biotechnology subindustry, PepGen's Moat Score, along with its competitors' market caps and Moat Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

PepGen Moat Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PepGen's Moat Score distribution charts can be found below:

* The bar in red indicates where PepGen's Moat Score falls into.


PEPG
32GF Score
PepGen Inc PEPG
Moat Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis
Frequently Asked Questions Learn more about Moat Score →
What does a Moat Score of 3 mean?
PepGen (PEPG) has a Moat Score of 3 as of Jul. 08, 2026. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. According to the industry distribution chart, PepGen ranks #341 out of 1393 companies in the Biotechnology industry, placing it in the top 24.5%.
Is PepGen's Moat Score too high?
PepGen's current Moat Score is 3. The Biotechnology industry median Moat Score is 2.00. PepGen's value of 3 is 50% above this industry median. Based on the distribution chart, PepGen ranks #341 out of 1393 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, PepGen has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does PepGen's Moat Score compare to ENGN and NTHI?
According to the Biotechnology industry distribution chart, PepGen ranks #341 out of 1393 companies for Moat Score. This places PepGen in the top 25% of its industry — outperforming the majority of peers. The industry median Moat Score is 2.00. PepGen's value of 3 is 50% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Moat Score for a Biotechnology company?
The median Moat Score among Biotechnology companies is 2.00, based on 1,393 companies in the industry. Companies in the top quartile (top 25%) have a Moat Score significantly above this median, while those in the bottom quartile fall well below. However, Moat Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. PepGen's current Moat Score of 3 is 50% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Moat Score mean?
A high Moat Score can signal that a stock is expensive relative to its fundamentals. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. For the Biotechnology industry, the median Moat Score is 2.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. PepGen's current Moat Score is 3. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PepGen stock overvalued right now?
PepGen (PEPG) has a current Moat Score of 3. The current Moat Score is 3 and 50% above the Biotechnology industry median of 2.00. PepGen's overall GF Score™ is 32/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Moat Score calculated?
Moat Score is calculated from a company's financial statements. For PepGen (PEPG), the current Moat Score is 3 as of Jul. 08, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

PepGen Business Description

Address 321 Harrison Avenue, 8th Floor, Boston, MA, USA, 02118
PepGen Inc is a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapeutics to transform the treatment of severe neuromuscular and neurologic diseases. The company has developed its Enhanced Delivery Oligonucleotide platform to improve the uptake and activity of conjugated oligonucleotide therapeutics. Its EDO peptides are engineered to optimize tissue penetration, cellular uptake, and nuclear delivery, and in preclinical studies, it is observed that their ability to transport oligonucleotides into a broad range of target tissues, including smooth, skeletal, and cardiac muscle, and the central nervous system. Its pipeline products are: PGN-EDO51, PGN-EDODM1, and others.
32GF Score

Get the complete analysis for PEPG

Moat Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.05
Price