VBIO (Valion Bio) Moat Score: 5/10 (As of Aug. 03, 2026)

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VBIO Valion Bio Inc VBIO
23 GF Score
Price $0.32
! 1 Warning Sign
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What is Valion Bio Moat Score?

Valion Bio VBIO +2.76% 23 Moat Score is 5 as of Aug. 03, 2026. GuruFocus rates VBIO with a GF Score™ of 23/100. The stock has 1 warning sign investors should review. Among 1,394 Biotechnology companies, Valion Bio ranks better than 96.7% on this metric.

Valion Bio has the Moat Score of 5, which implies that the company might have Narrow Moat - Solid narrow moat.

Valion Bio has Narrow Moat: Valion Bio Inc has valuable intellectual property and patents in the biotech sector, providing some competitive edge. However, the lack of strong brand strength and customer loyalty limits its moat to a solid narrow level.

Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more.

The company's Moat Score is based on these criteria:

1. Market leadership and sustainable market share
2. Network effects and significant customer switching costs
3. Valuable intellectual property and patents
4. Strong brand strength and deep customer loyalty
5. Durable cost advantages (e.g., economies of scale, proprietary technology)
6. Significant regulatory barriers and exclusive licenses
7. Superior distribution network
8. Strong and sustainable pricing power
9. Consistent and impactful innovation and R&D capabilities

Based on the research, GuruFocus believes Valion Bio might have Narrow Moat - Solid narrow moat.

Valion Bio  (NAS:VBIO) Moat Score Explanation

The Moat Score ranges from 0 to 10, with 10 as the highest. GuruFocus divided Moat Score into following 8 categories:

Moat Score Moat Level
10Wide Moat - Exceptionally dominant and durable wide moat
8 - 9Wide Moat - Clear and robust wide moat
7Wide Moat - Entry-level wide moat, clearly possessing durable advantages
6Narrow Moat - Strong narrow moat, clearly distinguishable but not wide
5Narrow Moat - Solid narrow moat
4Narrow Moat - Discernible but modest moat
1 - 3No Moat - Very weak/transient advantages
0No Moat - No discernible moat

Valion Bio Moat Score Related Terms

VBIO vs ZVSA, LYRA, ATXI: Moat Score Comparison

For the Biotechnology subindustry, Valion Bio's Moat Score, along with its competitors' market caps and Moat Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Valion Bio Moat Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Valion Bio's Moat Score distribution charts can be found below:

* The bar in red indicates where Valion Bio's Moat Score falls into.


VBIO
23GF Score
Valion Bio Inc VBIO
Moat Score is just one metric. See GF Score™, valuation, warning signs, and more.
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Frequently Asked Questions Learn more about Moat Score →
What does a Moat Score of 5 mean?
Valion Bio (VBIO) has a Moat Score of 5 as of Aug. 03, 2026. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. According to the industry distribution chart, Valion Bio ranks #46 out of 1394 companies in the Biotechnology industry, placing it in the top 3.3%.
Is Valion Bio's Moat Score too high?
Valion Bio's current Moat Score is 5. The Biotechnology industry median Moat Score is 2.00. Valion Bio's value of 5 is 150% above this industry median. Based on the distribution chart, Valion Bio ranks #46 out of 1394 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Valion Bio has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Valion Bio's Moat Score compare to ZVSA and LYRA?
According to the Biotechnology industry distribution chart, Valion Bio ranks #46 out of 1394 companies for Moat Score. This places Valion Bio in the top 3% of its industry — outperforming the majority of peers. The industry median Moat Score is 2.00. Valion Bio's value of 5 is 150% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Moat Score for a Biotechnology company?
The median Moat Score among Biotechnology companies is 2.00, based on 1,394 companies in the industry. Companies in the top quartile (top 25%) have a Moat Score significantly above this median, while those in the bottom quartile fall well below. However, Moat Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Valion Bio's current Moat Score of 5 is 150% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Moat Score mean?
A high Moat Score can signal that a stock is expensive relative to its fundamentals. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. For the Biotechnology industry, the median Moat Score is 2.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Valion Bio's current Moat Score is 5. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Valion Bio stock overvalued right now?
Valion Bio (VBIO) has a current Moat Score of 5. The current Moat Score is 5 and 150% above the Biotechnology industry median of 2.00. Valion Bio's overall GF Score™ is 23/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Moat Score calculated?
Moat Score is calculated from a company's financial statements. For Valion Bio (VBIO), the current Moat Score is 5 as of Aug. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Valion Bio Business Description

Address 1305 East Houston Street, Suite 311, Building 1, San Antonio, TX, USA, 78205
Valion Bio Inc is a late-stage biopharmaceutical company developing biologics that activate innate immune pathways for cytoprotection and immune modulation. Its main candidate, Entolimod, is a TLR5 agonist and also advances Entolasta, a next-generation TLR5 agonist, and targets the neutropenia oncology supportive care market.
23GF Score

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