CUE (Cue Biopharma) Net Margin %: -91.07% (As of Mar. 2026)


CUE Cue Biopharma Inc CUE
59 GF Score
Price $26.01
GF Value $62.11
Valuation Possible Value Trap
! 3 Warning Signs
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What is Cue Biopharma Net Margin %?

Cue Biopharma CUE -3.38% 59 Net Margin % is -91.07% as of Mar. 2026. GuruFocus rates CUE with a GF Score™ of 59/100 and a GF Value™ of $62.11 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 947 Biotechnology companies, Cue Biopharma ranks better than 53.43% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Cue Biopharma's Net Income for the three months ended in Mar. 2026 was $-5.18 Mil. Cue Biopharma's Revenue for the three months ended in Mar. 2026 was $5.69 Mil. Therefore, Cue Biopharma's net margin for the quarter that ended in Mar. 2026 was -91.07%.

The historical rank and industry rank for Cue Biopharma's Net Margin % or its related term are showing as below:

CUE' s Net Margin % Range Over the Past 10 Years
Min: -4257.83   Med: -992.69   Max: -59.65
Current: -59.65


CUE's Net Margin % is ranked better than
53.43% of 947 companies
in the Biotechnology industry
Industry Median: -89.33 vs CUE: -59.65

Cue Biopharma  (NAS:CUE) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Cue Biopharma Net Margin % Related Terms


Cue Biopharma Net Margin % Historical Data

* Premium members only.

The historical data trend for Cue Biopharma's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cue Biopharma Net Margin % Chart

Cue Biopharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -295.57 -4,257.83 -924.10 -437.97 -96.85

Cue Biopharma Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2,911.40 -287.14 -346.58 7.22 -91.07

CUE vs TELO, ACET, AARD: Net Margin % Comparison

For the Biotechnology subindustry, Cue Biopharma's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cue Biopharma Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cue Biopharma's Net Margin % distribution charts can be found below:

* The bar in red indicates where Cue Biopharma's Net Margin % falls into.


CUE
59GF Score
Cue Biopharma Inc CUE
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Cue Biopharma Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Cue Biopharma's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-26.602/27.466
=-96.85 %

Cue Biopharma's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-5.178/5.686
=-91.07 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -91.07% mean?
Cue Biopharma (CUE) has a Net Margin % of -91.07% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Cue Biopharma and its competitors. According to the industry distribution chart, Cue Biopharma ranks #441 out of 947 companies in the Biotechnology industry, placing it in the top 46.6%.
Is Cue Biopharma's Net Margin % too high?
Cue Biopharma's current Net Margin % is -91.07%. Based on the distribution chart, Cue Biopharma ranks #441 out of 947 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Cue Biopharma has a GF Score™ of 59/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Cue Biopharma's Net Margin % compare to TELO and ACET?
According to the Biotechnology industry distribution chart, Cue Biopharma ranks #441 out of 947 companies for Net Margin %. This puts Cue Biopharma in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Cue Biopharma and its competitors. Cue Biopharma's current Net Margin % is -91.07%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cue Biopharma stock overvalued right now?
Based on GuruFocus' analysis, Cue Biopharma (CUE) is currently considered Possible Value Trap. The stock's GF Value™ is $62.11, compared to a current price of $26.01 — trading 58.1% below its estimated fair value. The current Net Margin % is -91.07%. Cue Biopharma's overall GF Score™ is 59/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Cue Biopharma (CUE), the current Net Margin % is -91.07% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cue Biopharma (CUE) Overvalued in 2026?

Based on GuruFocus' analysis, Cue Biopharma stock appears to be undervalued. The current stock price of $26.01 is trading 58.1% below its estimated GF Value™ of $62.11. GuruFocus considers Cue Biopharma to be Possible Value Trap.

Key valuation signals for CUE:

  • Net Margin %: -91.07%
  • GF Value™: $62.11 vs. price of $26.01 (58.1% below fair value)
  • GF Score™: 59/100 with 3 warning signs

No single metric tells the full story. See the CUE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cue Biopharma Business Description

Other Exchanges 1UC0:Germany
Address 40 Guest Street, Boston, MA, USA, 02135
Cue Biopharma Inc is a clinical-stage therapeutics company focused on advancing a robust portfolio of potentially transformative therapies aimed at enabling functional cures across immunological disorders. Its product pipeline includes CUE-221, an anti-IgE antibody candidate being developed for allergic diseases. The company has also developed the Immuno-STAT platform for targeting disease-related T cells and is developing CUE-401, an IL-2 and TGF-B therapeutic candidate for autoimmune diseases.
59GF Score

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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$26.01
Price
$62.11
GF Value