CUE (Cue Biopharma) OCF Margin %: -192.44% (As of Mar. 2026)

What is Cue Biopharma OCF Margin %?

Cue Biopharma CUE -3.38% 59 OCF Margin % is -192.44% as of Mar. 2026. GuruFocus rates CUE with a GF Score™ of 59/100 and a GF Value™ of $62.11 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 960 Biotechnology companies, Cue Biopharma ranks worse than 50.73% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. Cue Biopharma's Cash Flow from Operations for the three months ended in Mar. 2026 was $-10.94 Mil. Cue Biopharma's Revenue for the three months ended in Mar. 2026 was $5.69 Mil. Therefore, Cue Biopharma's OCF Margin % for the quarter that ended in Mar. 2026 was -192.44%.

As of today, Cue Biopharma's current OCF Yield % is -22.39%.

The historical rank and industry rank for Cue Biopharma's OCF Margin % or its related term are showing as below:

CUE' s OCF Margin % Range Over the Past 10 Years
Min: -3357.91 Med: -809.25 Max: -78.96
Current: -74.72

During the past 11 years, the highest OCF Margin % of Cue Biopharma was -78.96%. The lowest was -3357.91%. And the median was -809.25%.

CUE's OCF Margin % is ranked worse than
50.73% of 960 companies
in the Biotechnology industry
Industry Median: -68.59 vs CUE: -74.72

Cue Biopharma OCF Margin % Related Terms

Cue Biopharma OCF Margin % Historical Data

* Premium members only.

The historical data trend for Cue Biopharma's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cue Biopharma OCF Margin % Chart

Cue Biopharma Annual Data

Trend

Dec16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

OCF Margin %

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-259.94

-3,357.91

-727.89

-391.18

-78.96

Cue Biopharma Quarterly Data
	Jun21	Sep21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
OCF Margin %	Get a 7-Day Free Trial															-1,941.09	-115.61	-419.92	-4.90	-192.44

CUE vs TELO, ACET, AARD: OCF Margin % Comparison

For the Biotechnology subindustry, Cue Biopharma's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Cue Biopharma OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cue Biopharma's OCF Margin % distribution charts can be found below:

* The bar in red indicates where Cue Biopharma's OCF Margin % falls into.

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59GF Score

Cue Biopharma Inc CUE

OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.

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Cue Biopharma OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

Cue Biopharma's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin	=	Cash Flow from Operations (A: Dec. 2025 )	/	Revenue (A: Dec. 2025 )
	=	-21.687	/	27.466
	=	-78.96 %

Cue Biopharma's OCF Margin for the quarter that ended in Mar. 2026 is calculated as

OCF Margin	=	Cash Flow from Operations (Q: Mar. 2026 )	/	Revenue (Q: Mar. 2026 )
	=	-10.942	/	5.686
	=	-192.44 %

Frequently Asked Questions Learn more about OCF Margin % →

What does a OCF Margin % of -192.44% mean?

Cue Biopharma (CUE) has a OCF Margin % of -192.44% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Cue Biopharma and its competitors. According to the industry distribution chart, Cue Biopharma ranks #487 out of 960 companies in the Biotechnology industry, placing it in the top 50.7%.

Is Cue Biopharma's OCF Margin % too high?

Cue Biopharma's current OCF Margin % is -192.44%. Based on the distribution chart, Cue Biopharma ranks #487 out of 960 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Cue Biopharma has a GF Score™ of 59/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.

How does Cue Biopharma's OCF Margin % compare to TELO and ACET?

According to the Biotechnology industry distribution chart, Cue Biopharma ranks #487 out of 960 companies for OCF Margin %. This places Cue Biopharma in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good OCF Margin % for a Biotechnology company?

A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high OCF Margin % mean?

A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Cue Biopharma and its competitors. Cue Biopharma's current OCF Margin % is -192.44%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is Cue Biopharma stock overvalued right now?

Based on GuruFocus' analysis, Cue Biopharma (CUE) is currently considered Possible Value Trap. The stock's GF Value™ is $62.11, compared to a current price of $26.01 — trading 58.1% below its estimated fair value. The current OCF Margin % is -192.44%. Cue Biopharma's overall GF Score™ is 59/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is OCF Margin % calculated?

OCF Margin % is calculated from a company's financial statements. For Cue Biopharma (CUE), the current OCF Margin % is -192.44% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cue Biopharma (CUE) Overvalued in 2026?

Based on GuruFocus' analysis, Cue Biopharma stock appears to be undervalued. The current stock price of $26.01 is trading 58.1% below its estimated GF Value™ of $62.11. GuruFocus considers Cue Biopharma to be Possible Value Trap.

Key valuation signals for CUE:

OCF Margin %: -192.44%
GF Value™: $62.11 vs. price of $26.01 (58.1% below fair value)
GF Score™: 59/100 with 3 warning signs

No single metric tells the full story. See the CUE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Cue Biopharma Business Description

Industry Healthcare Biotechnology

Comparable Companies TELO ACET AARD OKYO SGMO ANIX PYPD LONA ICCC NRXS VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY RVMD ASX:CSL ONC XKRX:068270

Other Exchanges 1UC0:Germany

Address 40 Guest Street, Boston, MA, USA, 02135

Website https://www.cuebiopharma.com

Cue Biopharma Inc is a clinical-stage therapeutics company focused on advancing a robust portfolio of potentially transformative therapies aimed at enabling functional cures across immunological disorders. Its product pipeline includes CUE-221, an anti-IgE antibody candidate being developed for allergic diseases. The company has also developed the Immuno-STAT platform for targeting disease-related T cells and is developing CUE-401, an IL-2 and TGF-B therapeutic candidate for autoimmune diseases.

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$26.01

Price

$62.11

GF Value

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