Ultragenyx Pharmaceutical (MEX:RARE) Net Margin %: -136.03% (As of Mar. 2026)

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MEX:RARE Ultragenyx Pharmaceutical Inc MEX:RARE
70 GF Score
Price MXN1,150.56
GF Value MXN1,699.44
! 5 Warning Signs
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What is Ultragenyx Pharmaceutical Net Margin %?

Ultragenyx Pharmaceutical MEX:RARE 70 Net Margin % is -136.03% as of Mar. 2026. GuruFocus rates MEX:RARE with a GF Score™ of 70/100 and a GF Value™ of MXN1,699.44. The stock has 5 warning signs investors should review. Among 941 Biotechnology companies, Ultragenyx Pharmaceutical ranks worse than 50.48% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Ultragenyx Pharmaceutical's Net Income for the three months ended in Mar. 2026 was MXN-3,336 Mil. Ultragenyx Pharmaceutical's Revenue for the three months ended in Mar. 2026 was MXN2,452 Mil. Therefore, Ultragenyx Pharmaceutical's net margin for the quarter that ended in Mar. 2026 was -136.03%.

The historical rank and industry rank for Ultragenyx Pharmaceutical's Net Margin % or its related term are showing as below:

MEX:RARE' s Net Margin % Range Over the Past 10 Years
Min: -184867.67   Med: -167.29   Max: -68.84
Current: -90.92


MEX:RARE's Net Margin % is ranked worse than
50.48% of 941 companies
in the Biotechnology industry
Industry Median: -88.29 vs MEX:RARE: -90.92

Ultragenyx Pharmaceutical  (MEX:RARE) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Ultragenyx Pharmaceutical Net Margin % Related Terms


Ultragenyx Pharmaceutical Net Margin % Historical Data

* Premium members only.

The historical data trend for Ultragenyx Pharmaceutical's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ultragenyx Pharmaceutical Net Margin % Chart

Ultragenyx Pharmaceutical Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -129.20 -194.71 -139.86 -101.61 -85.44

Ultragenyx Pharmaceutical Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -108.63 -69.04 -112.81 -62.02 -136.03

MEX:RARE vs VERA, IRON, QURE: Net Margin % Comparison

For the Biotechnology subindustry, Ultragenyx Pharmaceutical's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ultragenyx Pharmaceutical Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ultragenyx Pharmaceutical's Net Margin % distribution charts can be found below:

* The bar in red indicates where Ultragenyx Pharmaceutical's Net Margin % falls into.


MEX:RARE
70GF Score
Ultragenyx Pharmaceutical Inc MEX:RARE
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Ultragenyx Pharmaceutical Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Ultragenyx Pharmaceutical's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-10353.278/12117.836
=-85.44 %

Ultragenyx Pharmaceutical's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-3336.05/2452.447
=-136.03 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -136.03% mean?
Ultragenyx Pharmaceutical (MEX:RARE) has a Net Margin % of -136.03% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Ultragenyx Pharmaceutical and its competitors. According to the industry distribution chart, Ultragenyx Pharmaceutical ranks #475 out of 941 companies in the Biotechnology industry, placing it in the top 50.5%.
Is Ultragenyx Pharmaceutical's Net Margin % too high?
Ultragenyx Pharmaceutical's current Net Margin % is -136.03%. Based on the distribution chart, Ultragenyx Pharmaceutical ranks #475 out of 941 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Ultragenyx Pharmaceutical has a GF Score™ of 70/100, reflecting its overall financial health beyond just this single metric.
How does Ultragenyx Pharmaceutical's Net Margin % compare to VERA and IRON?
According to the Biotechnology industry distribution chart, Ultragenyx Pharmaceutical ranks #475 out of 941 companies for Net Margin %. This places Ultragenyx Pharmaceutical in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Ultragenyx Pharmaceutical and its competitors. Ultragenyx Pharmaceutical's current Net Margin % is -136.03%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ultragenyx Pharmaceutical stock overvalued right now?
Ultragenyx Pharmaceutical (MEX:RARE) has a current Net Margin % of -136.03%. The stock's GF Value™ is MXN1,699.44, compared to a current price of MXN1,150.56 — trading 32.3% below its estimated fair value. The current Net Margin % is -136.03%. Ultragenyx Pharmaceutical's overall GF Score™ is 70/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Ultragenyx Pharmaceutical (MEX:RARE), the current Net Margin % is -136.03% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ultragenyx Pharmaceutical (MEX:RARE) Overvalued in 2026?

Based on GuruFocus' analysis, Ultragenyx Pharmaceutical stock appears to be undervalued. The current stock price of MXN1,150.56 is trading 32.3% below its estimated GF Value™ of MXN1,699.44.

Key valuation signals for MEX:RARE:

  • Net Margin %: -136.03%
  • GF Value™: MXN1,699.44 vs. price of MXN1,150.56 (32.3% below fair value)
  • GF Score™: 70/100 with 5 warning signs

No single metric tells the full story. See the MEX:RARE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ultragenyx Pharmaceutical Business Description

Address 60 Leveroni Court, Novato, CA, USA, 94949
Ultragenyx Pharmaceutical Inc is a USA-based biopharmaceutical company. The company identifies, acquires, develops, and commercializes novel products for the treatment of serious, rare, and ultra-rare diseases, with a focus on debilitating genetic conditions. Its medicine portfolio includes Crysvita, Dojolvi, and Mepsevii. Crysvita is indicated for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients aged one year and older. Mepsevii is indicated for pediatric and adult patients for the treatment of Mucopolysaccharidosis VII. The company operates across North America, Latin America, Europe, the Middle East and Africa, and Asia-Pacific, with the majority of its revenue generated from North America.
70GF Score

Get the complete analysis for MEX:RARE

Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,150.56
Price
MXN1,699.44
GF Value