Ultragenyx Pharmaceutical (MEX:RARE) Return-on-Tangible-Asset: -61.98% (As of Mar. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

MEX:RARE Ultragenyx Pharmaceutical Inc MEX:RARE
69 GF Score
Price MXN1,150.56
GF Value MXN1,907.41
! 5 Warning Signs
View Full Analysis

What is Ultragenyx Pharmaceutical Return-on-Tangible-Asset?

Ultragenyx Pharmaceutical MEX:RARE 69 Return-on-Tangible-Asset is -61.98% as of Mar. 2026. GuruFocus rates MEX:RARE with a GF Score™ of 69/100 and a GF Value™ of MXN1,907.41. The stock has 5 warning signs investors should review. Among 1,416 Biotechnology companies, Ultragenyx Pharmaceutical ranks worse than 62.36% on this metric.

Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. Ultragenyx Pharmaceutical's annualized Net Income for the quarter that ended in Mar. 2026 was MXN-13,344 Mil. Ultragenyx Pharmaceutical's average total tangible assets for the quarter that ended in Mar. 2026 was MXN21,531 Mil. Therefore, Ultragenyx Pharmaceutical's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 was -61.98%.

The historical rank and industry rank for Ultragenyx Pharmaceutical's Return-on-Tangible-Asset or its related term are showing as below:

MEX:RARE' s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -71.48   Med: -45.51   Max: -14.65
Current: -54.94

During the past 13 years, Ultragenyx Pharmaceutical's highest Return-on-Tangible-Asset was -14.65%. The lowest was -71.48%. And the median was -45.51%.

MEX:RARE's Return-on-Tangible-Asset is ranked worse than
62.36% of 1416 companies
in the Biotechnology industry
Industry Median: -35.915 vs MEX:RARE: -54.94

Ultragenyx Pharmaceutical  (MEX:RARE) Return-on-Tangible-Asset Explanation

Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.


Be Aware

Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the company’s earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a company’s tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.


Ultragenyx Pharmaceutical Return-on-Tangible-Asset Related Terms


Ultragenyx Pharmaceutical Return-on-Tangible-Asset Historical Data

* Premium members only.

The historical data trend for Ultragenyx Pharmaceutical's Return-on-Tangible-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ultragenyx Pharmaceutical Return-on-Tangible-Asset Chart

Ultragenyx Pharmaceutical Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Asset
Get a 7-Day Free Trial Premium Member Only Premium Member Only -31.49 -51.29 -43.04 -48.99 -41.13

Ultragenyx Pharmaceutical Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -50.40 -40.47 -69.09 -44.65 -61.98

MEX:RARE vs VERA, IRON, QURE: Return-on-Tangible-Asset Comparison

For the Biotechnology subindustry, Ultragenyx Pharmaceutical's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ultragenyx Pharmaceutical Return-on-Tangible-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ultragenyx Pharmaceutical's Return-on-Tangible-Asset distribution charts can be found below:

* The bar in red indicates where Ultragenyx Pharmaceutical's Return-on-Tangible-Asset falls into.


MEX:RARE
69GF Score
Ultragenyx Pharmaceutical Inc MEX:RARE
Return-on-Tangible-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ultragenyx Pharmaceutical Return-on-Tangible-Asset Calculation

Ultragenyx Pharmaceutical's annualized Return-on-Tangible-Asset for the fiscal year that ended in Dec. 2025 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-10353.278/( (26716.152+23623.478)/ 2 )
=-10353.278/25169.815
=-41.13 %

Ultragenyx Pharmaceutical's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-13344.2/( (23623.478+19439.25)/ 2 )
=-13344.2/21531.364
=-61.98 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data.

What does a Return-on-Tangible-Asset of -61.98% mean?
Ultragenyx Pharmaceutical (MEX:RARE) has a Return-on-Tangible-Asset of -61.98% as of Mar. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Ultragenyx Pharmaceutical and its competitors. According to the industry distribution chart, Ultragenyx Pharmaceutical ranks #883 out of 1416 companies in the Biotechnology industry, placing it in the top 62.4%.
Is Ultragenyx Pharmaceutical's Return-on-Tangible-Asset too high?
Ultragenyx Pharmaceutical's current Return-on-Tangible-Asset is -61.98%. Based on the distribution chart, Ultragenyx Pharmaceutical ranks #883 out of 1416 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Ultragenyx Pharmaceutical has a GF Score™ of 69/100, reflecting its overall financial health beyond just this single metric.
How does Ultragenyx Pharmaceutical's Return-on-Tangible-Asset compare to VERA and IRON?
According to the Biotechnology industry distribution chart, Ultragenyx Pharmaceutical ranks #883 out of 1416 companies for Return-on-Tangible-Asset. This places Ultragenyx Pharmaceutical in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Ultragenyx Pharmaceutical and its competitors. Ultragenyx Pharmaceutical's current Return-on-Tangible-Asset is -61.98%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ultragenyx Pharmaceutical stock overvalued right now?
Ultragenyx Pharmaceutical (MEX:RARE) has a current Return-on-Tangible-Asset of -61.98%. The stock's GF Value™ is MXN1,907.41, compared to a current price of MXN1,150.56 — trading 39.7% below its estimated fair value. The current Return-on-Tangible-Asset is -61.98%. Ultragenyx Pharmaceutical's overall GF Score™ is 69/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For Ultragenyx Pharmaceutical (MEX:RARE), the current Return-on-Tangible-Asset is -61.98% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ultragenyx Pharmaceutical (MEX:RARE) Overvalued in 2026?

Based on GuruFocus' analysis, Ultragenyx Pharmaceutical stock appears to be undervalued. The current stock price of MXN1,150.56 is trading 39.7% below its estimated GF Value™ of MXN1,907.41.

Key valuation signals for MEX:RARE:

  • Return-on-Tangible-Asset: -61.98%
  • GF Value™: MXN1,907.41 vs. price of MXN1,150.56 (39.7% below fair value)
  • GF Score™: 69/100 with 5 warning signs

No single metric tells the full story. See the MEX:RARE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ultragenyx Pharmaceutical Business Description

Address 60 Leveroni Court, Novato, CA, USA, 94949
Ultragenyx Pharmaceutical Inc is a USA-based biopharmaceutical company. The company identifies, acquires, develops, and commercializes novel products for the treatment of serious, rare, and ultra-rare diseases, with a focus on debilitating genetic conditions. Its medicine portfolio includes Crysvita, Dojolvi, and Mepsevii. Crysvita is indicated for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients aged one year and older. Mepsevii is indicated for pediatric and adult patients for the treatment of Mucopolysaccharidosis VII. The company operates across North America, Latin America, Europe, the Middle East and Africa, and Asia-Pacific, with the majority of its revenue generated from North America.
69GF Score

Get the complete analysis for MEX:RARE

Return-on-Tangible-Asset is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,150.56
Price
MXN1,907.41
GF Value