OBIO (Orchestra BioMed Holdings) Net Margin %: -26,994.32% (As of Jun. 2026)

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OBIO Orchestra BioMed Holdings Inc OBIO
42 GF Score
Price $5.81
GF Value $31.57
Valuation Possible Value Trap
! 6 Warning Signs
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What is Orchestra BioMed Holdings Net Margin %?

Orchestra BioMed Holdings OBIO +7.00% 42 Net Margin % is -26,994.32% as of Jun. 2026. GuruFocus rates OBIO with a GF Score™ of 42/100 and a GF Value™ of $31.57 (Possible Value Trap). The stock has 6 warning signs investors should review. Among 948 Biotechnology companies, Orchestra BioMed Holdings ranks worse than 61.18% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Orchestra BioMed Holdings's Net Income for the three months ended in Jun. 2026 was $-23.76 Mil. Orchestra BioMed Holdings's Revenue for the three months ended in Jun. 2026 was $0.09 Mil. Therefore, Orchestra BioMed Holdings's net margin for the quarter that ended in Jun. 2026 was -26,994.32%.

The historical rank and industry rank for Orchestra BioMed Holdings's Net Margin % or its related term are showing as below:

OBIO' s Net Margin % Range Over the Past 10 Years
Min: -2313.27   Med: -662.86   Max: 2942.97
Current: -184.6


OBIO's Net Margin % is ranked worse than
61.18% of 948 companies
in the Biotechnology industry
Industry Median: -75.55 vs OBIO: -184.60

Orchestra BioMed Holdings  (NAS:OBIO) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Orchestra BioMed Holdings Net Margin % Related Terms


Orchestra BioMed Holdings Net Margin % Historical Data

* Premium members only.

The historical data trend for Orchestra BioMed Holdings's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Orchestra BioMed Holdings Net Margin % Chart

Orchestra BioMed Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial 2,942.97 -951.26 -1,779.71 -2,313.27 -157.40

Orchestra BioMed Holdings Quarterly Data
Dec20 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2,316.15 -2,419.05 20.20 -18,810.00 -26,994.32

OBIO vs CYDY, IRD, VNDA: Net Margin % Comparison

For the Biotechnology subindustry, Orchestra BioMed Holdings's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Orchestra BioMed Holdings Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Orchestra BioMed Holdings's Net Margin % distribution charts can be found below:

* The bar in red indicates where Orchestra BioMed Holdings's Net Margin % falls into.


OBIO
42GF Score
Orchestra BioMed Holdings Inc OBIO
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Orchestra BioMed Holdings Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Orchestra BioMed Holdings's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-52.701/33.482
=-157.40 %

Orchestra BioMed Holdings's Net Margin for the quarter that ended in Jun. 2026 is calculated as

Net Margin=Net Income (Q: Jun. 2026 )/Revenue (Q: Jun. 2026 )
=-23.755/0.088
=-26,994.32 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -26,994.32% mean?
Orchestra BioMed Holdings (OBIO) has a Net Margin % of -26,994.32% as of Jun. 2026. Net margin is the ratio of total net income to net sales. View historical data on Orchestra BioMed Holdings and its competitors. According to the industry distribution chart, Orchestra BioMed Holdings ranks #580 out of 948 companies in the Biotechnology industry, placing it in the top 61.2%.
Is Orchestra BioMed Holdings' Net Margin % too high?
Orchestra BioMed Holdings' current Net Margin % is -26,994.32%. Based on the distribution chart, Orchestra BioMed Holdings ranks #580 out of 948 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Orchestra BioMed Holdings has a GF Score™ of 42/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Orchestra BioMed Holdings' Net Margin % compare to CYDY and IRD?
According to the Biotechnology industry distribution chart, Orchestra BioMed Holdings ranks #580 out of 948 companies for Net Margin %. This places Orchestra BioMed Holdings in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Orchestra BioMed Holdings and its competitors. Orchestra BioMed Holdings's current Net Margin % is -26,994.32%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Orchestra BioMed Holdings stock overvalued right now?
Based on GuruFocus' analysis, Orchestra BioMed Holdings (OBIO) is currently considered Possible Value Trap. The stock's GF Value™ is $31.57, compared to a current price of $5.81 — trading 81.6% below its estimated fair value. The current Net Margin % is -26,994.32%. Orchestra BioMed Holdings' overall GF Score™ is 42/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Orchestra BioMed Holdings (OBIO), the current Net Margin % is -26,994.32% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Orchestra BioMed Holdings (OBIO) Overvalued in 2026?

Based on GuruFocus' analysis, Orchestra BioMed Holdings stock appears to be undervalued. The current stock price of $5.81 is trading 81.6% below its estimated GF Value™ of $31.57. GuruFocus considers Orchestra BioMed Holdings to be Possible Value Trap.

Key valuation signals for OBIO:

  • Net Margin %: -26,994.32%
  • GF Value™: $31.57 vs. price of $5.81 (81.6% below fair value)
  • GF Score™: 42/100 with 6 warning signs

No single metric tells the full story. See the OBIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Orchestra BioMed Holdings Business Description

Address 150 Union Square Drive, New Hope, PA, USA, 18938
Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
42GF Score

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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.81
Price
$31.57
GF Value