OBIO (Orchestra BioMed Holdings) GF Value Rank: 2 (As of Sep. 11, 2026) — Near Median

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Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

OBIO Orchestra BioMed Holdings Inc OBIO
42 GF Score
Price $5.81
GF Value $31.57
Valuation Possible Value Trap
! 6 Warning Signs
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What is Orchestra BioMed Holdings GF Value Rank?

Orchestra BioMed Holdings OBIO +7.00% 42 GF Value Rank is 2 as of Sep. 11, 2026, which is at its 10-year median of 2.00. GuruFocus rates OBIO with a GF Score™ of 42/100 and a GF Value™ of $31.57 (Possible Value Trap). The stock has 6 warning signs investors should review.

Orchestra BioMed Holdings has the GF Value Rank of 2.

GF Value Rank evaluates the exclusive GuruFocus valuation and performance of a stock, rated on a scale from 1 to 10. It is determined by the price-to-GF-Value (P/GF Value) ratio, a proprietary metric calculated based on historical multiples along with an adjustment factor based on a company's past returns and growth and future estimates of the business' performance.

GuruFocus found that for valuation, we cannot simply give stocks a better GF Value rank simply because they have a lower P/GF Value ratio. Backtesting shows that over the long term, the two worst-performing groups are the most expensive group (with the highest P/GF Value ratio) and the least expensive group (with the lowest P/GF Value ratio).

We can understand why the most expensive group underperforms. We were initially puzzled by the underperformance of the least expensive group, but we realized there is a reason why some stocks are super cheap. If they look too undervalued, it is often because the businesses behind them are poor quality. The market realized this and gave them low valuations. In a way, the market is efficient.

After multiple backtesting analyses, we granted the stocks in third-cheapest percentile the highest GF Value rank, as they have performed the best over a full market cycle. Stock performance is actually not as sensitive to valuation as it is to growth and profitability. On average, the companies in the 20%-50% valuation groups have similar performances. Therefore, we should avoid the most expensive and the least expensive stocks. We can be more tolerant of valuation.

A higher score indicates a stock with a relatively low valuation and substantial potential for outperformance. Conversely, a lower score often reflects stocks that are either highly overvalued or deeply undervalued, both of which tend to underperform.

Please click GF Score to see more details on the GF Score's 5 Key Aspects of Analysis.


Orchestra BioMed Holdings GF Value Rank Related Terms


OBIO vs CYDY, IRD, VNDA: GF Value Rank Comparison

For the Biotechnology subindustry, Orchestra BioMed Holdings's GF Value Rank, along with its competitors' market caps and GF Value Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Orchestra BioMed Holdings GF Value Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Orchestra BioMed Holdings's GF Value Rank distribution charts can be found below:

* The bar in red indicates where Orchestra BioMed Holdings's GF Value Rank falls into.


OBIO
42GF Score
Orchestra BioMed Holdings Inc OBIO
GF Value Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Frequently Asked Questions Learn more about GF Value Rank →
What does a GF Value Rank of 2 mean?
Orchestra BioMed Holdings (OBIO) has a GF Value Rank of 2 as of Sep. 11, 2026. GF Value Rank is given based on historical multiples along with past returns, growth and future estimates of the business' performance. View historical data on Orchestra BioMed Holdings and its competitors. This is near median its historical median of 2.00. Over the past decade, Orchestra BioMed Holdings' GF Value Rank has ranged from 2.00 to 9.00.
Is Orchestra BioMed Holdings' GF Value Rank too high?
Orchestra BioMed Holdings' current GF Value Rank of 2 is near median its 10-year median of 2.00. Over the past 10 years, this metric has ranged from a low of 2.00 to a high of 9.00. Overall, Orchestra BioMed Holdings has a GF Score™ of 42/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Orchestra BioMed Holdings' GF Value Rank compare to CYDY and IRD?
Orchestra BioMed Holdings' GF Value Rank of 2 can be compared against companies in the Biotechnology industry. Historically, Orchestra BioMed Holdings' own GF Value Rank has ranged from 2.00 to 9.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good GF Value Rank for a Biotechnology company?
A good GF Value Rank depends on the Biotechnology industry context. However, GF Value Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high GF Value Rank mean?
A high GF Value Rank can signal that a stock is expensive relative to its fundamentals. GF Value Rank is given based on historical multiples along with past returns, growth and future estimates of the business' performance. View historical data on Orchestra BioMed Holdings and its competitors. Orchestra BioMed Holdings's current GF Value Rank is 2, which is near median its own 10-year median of 2.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Orchestra BioMed Holdings stock overvalued right now?
Based on GuruFocus' analysis, Orchestra BioMed Holdings (OBIO) is currently considered Possible Value Trap. The stock's GF Value™ is $31.57, compared to a current price of $5.81 — trading 81.6% below its estimated fair value. The current GF Value Rank is 2, which is near median its 10-year median of 2.00. Orchestra BioMed Holdings' overall GF Score™ is 42/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is GF Value Rank calculated?
GF Value Rank is calculated from a company's financial statements. For Orchestra BioMed Holdings (OBIO), the current GF Value Rank is 2 as of Sep. 11, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Orchestra BioMed Holdings (OBIO) Overvalued in 2026?

Based on GuruFocus' analysis, Orchestra BioMed Holdings stock appears to be undervalued. The current stock price of $5.81 is trading 81.6% below its estimated GF Value™ of $31.57. GuruFocus considers Orchestra BioMed Holdings to be Possible Value Trap.

Key valuation signals for OBIO:

  • GF Value Rank: 2 (near median its 10-year median of 2.00)
  • GF Value™: $31.57 vs. price of $5.81 (81.6% below fair value)
  • GF Score™: 42/100 with 6 warning signs

No single metric tells the full story. See the OBIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Orchestra BioMed Holdings Business Description

Address 150 Union Square Drive, New Hope, PA, USA, 18938
Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
42GF Score

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GF Value Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.81
Price
$31.57
GF Value