CCCC (C4 Therapeutics) OCF Margin %: -23.70% (As of Jun. 2026)

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CCCC C4 Therapeutics Inc CCCC
49 GF Score
Price $4.12
GF Value $2.05
Valuation Significantly Overvalued
! 7 Warning Signs
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What is C4 Therapeutics OCF Margin %?

C4 Therapeutics CCCC +2.50% 49 OCF Margin % is -23.70% as of Jun. 2026. GuruFocus rates CCCC with a GF Score™ of 49/100 and a GF Value™ of $2.05 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 956 Biotechnology companies, C4 Therapeutics ranks worse than 64.96% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. C4 Therapeutics's Cash Flow from Operations for the three months ended in Jun. 2026 was $-1.57 Mil. C4 Therapeutics's Revenue for the three months ended in Jun. 2026 was $6.64 Mil. Therefore, C4 Therapeutics's OCF Margin % for the quarter that ended in Jun. 2026 was -23.70%.

As of today, C4 Therapeutics's current OCF Yield % is -16.76%.

The historical rank and industry rank for C4 Therapeutics's OCF Margin % or its related term are showing as below:

CCCC' s OCF Margin % Range Over the Past 10 Years
Min: -514.73   Med: -196.27   Max: 260.11
Current: -242.22


During the past 8 years, the highest OCF Margin % of C4 Therapeutics was 260.11%. The lowest was -514.73%. And the median was -196.27%.

CCCC's OCF Margin % is ranked worse than
64.96% of 956 companies
in the Biotechnology industry
Industry Median: -69.685 vs CCCC: -242.22


C4 Therapeutics OCF Margin % Related Terms


C4 Therapeutics OCF Margin % Historical Data

* Premium members only.

The historical data trend for C4 Therapeutics's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

C4 Therapeutics OCF Margin % Chart

C4 Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Margin %
Get a 7-Day Free Trial -189.94 -340.68 -514.73 -183.11 -274.55

C4 Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -186.55 -277.89 -201.03 -486.74 -23.70

CCCC vs CMPX, AVIR, STRO: OCF Margin % Comparison

For the Biotechnology subindustry, C4 Therapeutics's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


C4 Therapeutics OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, C4 Therapeutics's OCF Margin % distribution charts can be found below:

* The bar in red indicates where C4 Therapeutics's OCF Margin % falls into.


CCCC
49GF Score
C4 Therapeutics Inc CCCC
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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C4 Therapeutics OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

C4 Therapeutics's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-98.694/35.947
=-274.55 %

C4 Therapeutics's OCF Margin for the quarter that ended in Jun. 2026 is calculated as

OCF Margin=Cash Flow from Operations (Q: Jun. 2026 )/Revenue (Q: Jun. 2026 )
=-1.574/6.641
=-23.70 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -23.70% mean?
C4 Therapeutics (CCCC) has a OCF Margin % of -23.70% as of Jun. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on C4 Therapeutics and its competitors. According to the industry distribution chart, C4 Therapeutics ranks #621 out of 956 companies in the Biotechnology industry, placing it in the top 65%.
Is C4 Therapeutics' OCF Margin % too high?
C4 Therapeutics' current OCF Margin % is -23.70%. Based on the distribution chart, C4 Therapeutics ranks #621 out of 956 companies in the Biotechnology industry, which is below the industry midpoint. Overall, C4 Therapeutics has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does C4 Therapeutics' OCF Margin % compare to CMPX and AVIR?
According to the Biotechnology industry distribution chart, C4 Therapeutics ranks #621 out of 956 companies for OCF Margin %. This places C4 Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on C4 Therapeutics and its competitors. C4 Therapeutics's current OCF Margin % is -23.70%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is C4 Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, C4 Therapeutics (CCCC) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.05, compared to a current price of $4.12 — trading 100.7% above its estimated fair value. The current OCF Margin % is -23.70%. C4 Therapeutics' overall GF Score™ is 49/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For C4 Therapeutics (CCCC), the current OCF Margin % is -23.70% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is C4 Therapeutics (CCCC) Overvalued in 2026?

Based on GuruFocus' analysis, C4 Therapeutics stock appears to be overvalued. The current stock price of $4.12 is trading 100.7% above its estimated GF Value™ of $2.05. GuruFocus considers C4 Therapeutics to be Significantly Overvalued.

Key valuation signals for CCCC:

  • OCF Margin %: -23.70%
  • GF Value™: $2.05 vs. price of $4.12 (100.7% above fair value)
  • GF Score™: 49/100 with 7 warning signs

No single metric tells the full story. See the CCCC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


C4 Therapeutics Business Description

Address 490 Arsenal Way, Suite 120, Watertown, MA, USA, 02472
C4 Therapeutics Inc is a clinical-stage biopharmaceutical company dedicated to delivering on the promise of targeted protein degradation science to create a new generation of medicines that transforms patient's lives. The Company is progressing targeted oncology programs through clinical studies and leveraging its TORPEDO platform to efficiently design and optimize small-molecule medicines to address difficult-to-treat diseases. The degrader medicines of the company are designed to harness the body's natural protein recycling system to rapidly degrade disease-causing proteins, offering the potential to overcome drug resistance, and drug undruggable targets and improve patient outcomes. Its pipeline is Cemsidomide, CFT8919, and other discovery products.
49GF Score

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OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.12
Price
$2.05
GF Value